Top 6 things that shocked me when researching in gene editing #WorldCRISPRDay
- Sometimes editing efficiency can be as low as 5%, yet you will still see a change in phenotype.
- The genome is truly strong and delicate at the same time.
- Chromatin folding can make or break your target.
Current and future applications of Class 1 systems.
It’s #WorldCRISPRday! To celebrate, revisit this #JBiolChem review: www.jbc.org/article/S002....
Tina Liu and @jenniferdoudna.bsky.social explore how Class 1 CRISPR-Cas systems are expanding possibilities for DNA/RNA editing, gene expression control and nucleic acid detection.
13 years ago, the revolutionary genetic tool #CRISPR/Cas9 was published in Science, work that Emmanuelle Charpentier and Jennifer Doudna won a #NobelPrize for in 2020.
On #WorldCRISPRDay, read the landmark paper that describes the discovery: https://scim.ag/42JHuSN
An informational graphic about CRISPR-based Therapies. At the top is a header that says, “The Wyss Effect.” Then there is a headline that reads, “CRISPR-based Therapies, Ending the global transplant shortage with genetic engineering.” Then there are four subtitles that read, “Healthy Aging,” “Therapeutics,” “Organ Transplantation,” and “Genetics.” Then, there is a timeline that goes along the shape of a nautilus shell. The entries say, “2013 CRISPR-Cas9 used for precise targeted gene editing in mammalian cells,” “2014 Editas Launched,” “2015 eGenesis Founded,” “2019 Vertex Tx Launched,” “2023 First FDA-Approved CRISPR Therapy,” “2024 First Human Transplant,” “2025 FDA Approval for Clinical Trial.” At the bottom, it says, “3-patient clinical trial underway.”
Transforming breakthrough science, like the use of CRISPR-Cas9 for precise targeted gene editing in mammalian cells, into a cascade of innovations, like genetically modified pig kidneys that can be transplanted into humans – that’s the power of the Wyss Effect. #WorldCRISPRDay
bit.ly/3R5VX59
Reminder since it's #WorldCRISPRDay
#GenomeEditing #CRISPR #BMCBiology
🧪 🧬 ✂️
👉 One of my Favorite things!
#EvoDevo (#Despacito Biology #Parody) | #ACapellaScience
#WorldCRISPrDay!
youtu.be/ydqReeTV_vk
✂️🧬 October 20th is #WorldCRISPRDay!
Want to learn more about the gene editing technology? Gain a basic understanding of CRISPR/Cas9 in @jacksonlab.bsky.social's free online course: education.learning.jax.org/basics-of-cr...
Today we celebrate #WorldCRISPRDay, marking 11 incredible years since the CRISPR/Cas9 was shared in Science! 🎉E. Charpentier & J. Doudna’s work revolutionized molecular biology. Immerse yourself in the original paper to explore the genesis of this discovery! 🧬
#molecularbiology #CRISPR #academicsky
#HumanNatureFilm producers (and @ibiology @wondercollab team members) Sarah Goodwin and Elliot Kirschner will speak on the future of #CRISPR as part of #WorldCRISPRDay Oct 20 https://youtu.be/RU-0XMsptkU #NobelLaureate Jennifer Doudna will keynote. Register 👉🏽...
