Standard #CRISPR couldn’t crack a #PDL1 knockout in #PC3 cells at the #UniPadova #UniversityPadua.
#CellEDIT’s direct nuclear injection enabled a verified homozygous #KO and rapid validation. 👉 https://bit.ly/4bInAg4

#GeneEditing #AdoptiveCellTherapy #ProstateCancer #CancerResearch #Biotech

⭐️Great first session on #AdoptiveCellTherapy chaired by Samra Turajlic

Starting w/ @haanenjohn.bsky.social
on #TIL #TCR, Sonia Guedan on #CART & Jeff Miller on #NKTherapy

Academic manufacturing is possible! We need to work w/ industry/regulators to move closer to #cure 🔥

#ESMO25

Beyond immune checkpoint blockade: what’s next for #melanoma?
At #ESMO25, explore:
📌 Why move beyond ICB
📌 #AdoptiveCellTherapy
📌 Treating unresectable stage IV melanoma
📌 Bispecific T-cell engagers
📅 17 Oct | 14:00–15:30

🔗 buff.ly/RaDTAFV

🔬 Why do some cancer patients respond to cell therapy while others don't?

We’re excited to answer this question in our next webinar: Decoding Adoptive Cell Therapy Response with ImmuneWatch.

Register here: shorturl.at/063UV

#CancerImmunology #AdoptiveCellTherapy #SingleCell #CellTherapy

📌 OncoTerm - Word of the Day! 👋

📌 OncoTerm - Günün Kelimesi! 👋

Join us as we break down key terms to empower ourselves with knowledge in the fight against cancer.

#Onco404 #Cancer #Kanser #CancerAwareness #TumorInfiltratingLymphocyte #TIL #AdoptiveCellTherapy #ACT #MedSky #OncSky #Vocabulary

Schematic T cell differentiation trajectories under chronic antigen stimulation towards exhaustion and approaches (immune checkpoint blockade, IL-10, and functional diversion) to promote potent T cell responses under exhaustion-inducing conditions, e.g., in tumor patients.

Hi! 👋 Wondering what's in this blackbox? In the Gattinoni lab at lit.eu, we're investigating physiological CD8 T cell differentiation to design strategies increasing cell fitness and in vivo efficacy up to clinical testing #adoptivecelltherapy #syntheticbiology #immunosky
Some recent examples:

Turning Anticancer Therapy Inside-Out (Part I): From Exogenous to Endogenous--Moving Treatment In Situ (via Passle) by @cellohealth #endogenousreprogramming #adoptivecelltherapy #insitu