New research uncovers the diverse structures of apolipoprotein A-I amyloid fibrils in various organs. How does this impact treatment? #Amyloidosis
https://www.nature.com/articles/s41467-026-72150-z
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Your Word of the Day is Mass Spectrometry: a highly sensitive analytical technique that identifies molecules by measuring their mass and chemical characteristics. In amyloidosis, it is used on tissue samples to precisely identify which type of amyloid protein is present, giving doctors a definitive foundation for accurate diagnosis and targeted treatment.
Your Word of the Day is…
Mass Spectrometry
A highly sensitive analytical technique that identifies molecules by measuring their mass & chemical characteristics. In #amyloidosis, it is used on tissue samples to identify which type of amyloid protein is present, enabling more accurate diagnosis…
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Your Word of the Day is Biomarker: a naturally occurring molecule, gene, or bodily characteristic that helps identify a disease or physiological process. In amyloidosis, biomarkers like troponin and NT-proBNP give doctors a measurable window into how organs are being affected and how well treatment is working.
Your Word of the Day is…
Biomarker
A naturally occurring molecule, gene, or bodily characteristic that helps identify a disease or physiological process. In #amyloidosis, biomarkers like troponin give doctors a measurable window into how organs are being affected and how well treatment is working.
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Free virtual 1.5 #CME on April 16 for clinicians involved in #amyloidosis care! This ARC and @bumedicine.bsky.social program covers early recognition & diagnosis of #ATTR, multimodality imaging, and treatments. HFSA endorsed.
Open to all specialties.
Register here: cme.bu.edu/arc25
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Better outcomes start with knowing your risk.
Join ARC 4/23 at 7PM ET for a webinar on #V122I hereditary #ATTR #amyloidosis. Specialists, a genetic counselor, and a patient will cover what the disease is, genetic testing, treatment, & more.
Register at: us02web.zoom.us/webinar/regi...
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In this video Keith Dares of the Canadian Amyloidosis Support Network provides one of the best explanations of what #amyloidosis is that we’ve ever come across.
If you’re struggling to explain it to somebody, keep this video around to share:
globalnews.ca/video/117236...
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George Symes is running the Paris Marathon 2026 on April 12 to raise money for our charity in memory of his Grandad Bryan, who sadly passed away from amyloidosis last year. Thank you George, we think you’re amazing!
George Symes is running the Paris Marathon 2026 on April 12 to raise money for our charity in memory of his Grandad Bryan, who sadly passed away from #amyloidosis last year.
Thank you George, we think you’re amazing!
NB George’s JustGiving page is still open:
www.justgiving.com/page/george-...
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#ARCTalks Webinar | April 14 | Noon ET
Learn what’s new in #AL (light chain) #amyloidosis clinical trials and what those updates mean for patients and families during this webinar from Kristen Hsu, ARC’s Executive Director of Research.
Register today: us02web.zoom.us/webinar/regi...
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Fresh funding backs a high-stakes attempt to do what current amyloidosis drugs still cannot: clear the buildup already damaging the heart.
Link as first comment.
#longevity #geroscience #amyloidosis #biotech #innovation
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For Libby, losing her nan to #amyloidosis was like losing the solid person in her life. She’d been a second mother to Libby from childhood into adulthood. Having cared for her nan for 4 years, seeing her deteriorate was extremely difficult, as was knowing where to turn for help
youtu.be/T8bwk9_HeWw
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ASE experts connect with industry partners to drive advances in the field like #Strain #3DEcho & #ArtificialIntelligence while focusing on disease diagnosis in #HCM #Amyloidosis #ValveDisease & more! bit.ly/4247EQ4
#ASEIRT #PartnersInInnovation #HeartofASE #ASEMemberDay
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Libby, who used to care for her nan who had #amyloidosis, talks about how the considerable challenges of that care put her life on hold for several years. Having been looked after by her nan growing up, she never questioned the calling & took it on from a place of love.
youtu.be/qR1XK51HjpQ
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This is big news for the #amyloidosis community…
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There’s still time to register for this important talk tomorrow and it is something we highly recommend doing whether you’re a patient, carer or healthcare professional dealing with #amyloidosis.
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#ARCTALKS Tomorrow! Join ARC and Dr. Melissa Hershman from Oregon Health & Science University at Noon ET to learn how #amyloidosis may be affecting your gut and what you can do about it!
Register Today: us02web.zoom.us/webinar/regi...
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What are the common myths about ATTR amyloidosis?
In this video Christine Chiti (Clinical TTR nurse specialist at the National Amyloidosis Centre) outlines some of the common myths & misconceptions about ATTR #amyloidosis, eg that you shouldn’t eat protein or go on holiday.
youtu.be/ojsPmoAy6Xs
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Through ACC’s Cardiac #Amyloidosis online course, build confidence in recognizing the key symptoms & clinical clues of cardiac amyloidosis, selecting the right diagnostic tests & understanding treatment pathways.
Learn more: https://bit.ly/46QADsV
#ACCEd #AmyloidosisAwareness #CardioSky #MedSky
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The #AmyloidosisForum Prognostic Factors working group just published a new review in Blood on prognostic factors and progression biomarkers in #AL #amyloidosis, as well as the critical need for updated validation studies.
Read the review: doi.org/10.1182/bloo...
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Wondering how #amyloidosis may be affecting your gut and what you can do about it?
Join ARC and Dr. Melissa Hershman from Oregon Health & Science University on March 18 at Noon ET for our next #ARCTalks Webinar!
Register Today: us02web.zoom.us/webinar/regi...
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What support is available in the UK for people living with ATTR #amyloidosis?
In this video Christine Chiti, a Clinical TTR nurse specialist at the National Amyloidosis Centre in London, provides an overview of the types of support people can access.
youtu.be/RdtL2iqtf4M
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Your Word of the Day is amyloid fibrils. These are abnormal proteins that build up in the body’s tissues and organs causing amyloidosis, a group of rare diseases. These amyloid fibril deposits can damage organs and, if left untreated, may lead to life-threatening complications.
Your Word of the Day is…
Amyloid Fibrils
Amyloid fibrils are abnormal proteins that build up in the body’s tissues and organs causing #Amyloidosis, a group of rare diseases. These amyloid fibril deposits can damage organs and, if left untreated, may lead to life-threatening complications.
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Read this comprehensive systematic review by Samuel Parker, Andrew F. James & Svetlana Mastitskaya from @bristoluni.bsky.social into the causative role of #amyloidosis in the cardiac complications of #Alzheimer's disease 🧠 🫀
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
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Your Word of the Day is: Fibrinogen — the precursor protein in AFib amyloidosis which mainly affects the kidneys. Produced in the liver, fibrinogen plays an important role in blood clotting, inflammation and wound healing. AFib amyloidosis is a hereditary condition — it is caused by variants in the fibrinogen gene that result in the liver making abnormal fibrinogen that misfolds and forms amyloid. This variant or mutation may be passed down in families from parent to child.
Your Word of the Day is…
Fibrinogen
Produced in the liver, fibrinogen is a protein that plays an important role in blood clotting, inflammation & wound healing. In AFib amyloidosis, which mainly affects the kidneys, the liver makes abnormal fibrinogen that misfolds & forms amyloid.
#amyloidosis
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Your Word of the Day is… Silencers (Gene silencers). These are a whole new class of medicines that have been developed in recent years to work at the source of a disease. In the case of ATTR amyloidosis, these drugs stop the TTR gene from making the abnormal protein (i.e. silencing the gene) that forms amyloid deposits. This can significantly halt or slow down the build up of amyloid in the body.
Your Word of the Day is…
Silencers (Gene silencers)
These are a whole new class of medicines that have been developed in recent years to work at the source of a disease. In the case of ATTR #amyloidosis, these drugs stop the TTR gene from making the abnormal protein that forms amyloid deposits.
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Your Word of the Day is… Apoptosis: defined as “the death of cells which occurs as a normal & controlled part of an organism’s growth or development.” This happens excessively in AL amyloidosis when misfolded proteins build up in tissues leading to tissue damage.
Here’s our ’Word of the Day’ to help boost your #amyloidosis vocabulary:
Apoptosis ¬
“The death of cells which occurs as a normal & controlled part of an organism’s growth or development.”
» Happens excessively in AL amyloidosis when misfolded proteins build up in tissues leading to tissue damage.
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We’d like to give a huge thanks to Finley Symon who has so far raised £3,140 for our charity in memory of his family’s loved one Janette Lefevre (Janny).
Finley is running the Inverness Half Marathon 2026 on 8 March to help raise awareness of #amyloidosis.
www.justgiving.com/page/jannys-...
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Isatuximab monotherapy shows significant clinical activity in R/R AL #amyloidosis:
• 77.1% overall hematologic response rate
• 1.1 months median time to response
• 57% cardiac response rate
From @bloodjournals.hematology.org Read more: ➡️ https://bit.ly/4qNGBBR
#Hematology #ClinicalTrials #MedSky
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A helpful article from @stonybrookmedicine.bsky.social about the links between carpal tunnel syndrome and #amyloidosis from a patient’s perspective:
“Carpal Tunnel Surgery May Reveal Early Amyloidosis: What You Should Know”
health.stonybrookmedicine.edu/amyloidosis-...
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#Amyloidosis #CardioAI #AIinMedicine #ECG #Echo #DigitalHealth #CardioX
Full manuscript: jamanetwork.com/journals/jam...
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Julia’s raising money in memory of her husband John in order to help raise awareness, understanding and support for #amyloidosis.
She’s only just launched her fundraising page, can you help her out with a donation?
www.justgiving.com/page/julia-b...
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