Scientists show #CyclicdiGMP inhibits #breastcancer #metastasis by binding #PSMD3, disrupting PSMD3–TBK1 interaction, and suppressing NF‑κB signaling, positioning PSMD3 as a therapeutic target. #Antimetastatic @tulanemedicine.bsky.social

#OpenAccess #STTT: doi.org/10.1038/s413...

A heterogenic fusion membrane #TumorVaccine (EV–CM) enhanced with a Pt‑porphyrin #nanoplatform was developed, showing ultrasound‑augmented immunogenic cell death, stronger #AntitumorImmunity, and #antimetastatic effects.

#OpenAccess in #STTT: doi.org/10.1038/s413...