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#antiplasmodial
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De Gruyter Brill - Innovations in Molecular & Materials Science
De Gruyter Brill - Innovations in Molecular & Materials Science
@degruyterbrillimms.bsky.social
3 months ago
Identified active site of receptors: Plasmepsin 1 (PDB ID: 3QS1) and plasmepsin 2 (PDB ID: 1LF2).

Identified active site of receptors: Plasmepsin 1 (PDB ID: 3QS1) and plasmepsin 2 (PDB ID: 1LF2).

This review highlights #EssentialOils from Brazilian plants with #AntiInflammatory and #AntiPlasmodial potential, revealing promising compounds with strong #plasmepsin binding and favorable pharmacokinetics.
#OpenAccess in Open Chemistry: doi.org/10.1515/chem...

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FEBS Letters
FEBS Letters
@febsletters.bsky.social
4 months ago
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💊 #Atovaquone (AV) is an #antiplasmodial drug. A recent study by Alejandro Miguel Katzin, Marcell Crispim et al. shows that 4-nitrobenzoate targets the 4-HPT enzyme and enhances in vitro antiplasmodial efficacy and selectivity of AV.

➡️ doi.org/10.1002/1873-3468.70186

#malaria

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