ICB
#Endosymbiotic #apicomplexans of marine #holobionts: microbial #parasites in a warming #ocean
@ambonacolta.bsky.social , & Keeling et al
doi.org/10.1093/icb/...
" novel apicomplexans with important #ecological roles are still being discovered..."
& see
www3.botany.ubc.ca/keeling/peop...
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Top: Model RNG2 as a molecular tether for conoid apical anchorage. Illustration of the consequences of RNG2 depletion on the apical complex structure of Toxoplasma gondii tachyzoites. Bottom: Toxoplasma gondii extracellular tachyzoite imaged through Ultrastructure-Expansion Microscopy and stained for tubulin (magenta ) and RNG2-mAID-HA (green). The original image has been modified for aesthetic purposes Credit : the data was produced by Romuald Haase and the image was designed by Albert Tell i Puig
The conoid is a structure in #Apicomplexans that extrudes during egress, gliding motility & invasion. This study shows that the coiled-coil protein RNG2 tethers the conoid to the apical polar ring in #Toxoplasma and is essential for invasion @plosbiology.org 🧪 plos.io/489blpq
Top: Model RNG2 as a molecular tether for conoid apical anchorage. Illustration of the consequences of RNG2 depletion on the apical complex structure of Toxoplasma gondii tachyzoites. Bottom: Toxoplasma gondii extracellular tachyzoite imaged through Ultrastructure-Expansion Microscopy and stained for tubulin (magenta ) and RNG2-mAID-HA (green). The original image has been modified for aesthetic purposes Credit : the data was produced by Romuald Haase and the image was designed by Albert Tell i Puig
The conoid is a structure in #Apicomplexans that extrudes during egress, gliding motility & invasion. This study shows that the coiled-coil protein RNG2 tethers the conoid to the apical polar ring in #Toxoplasma and is essential for invasion @plosbiology.org 🧪 plos.io/489blpq
Top: Model RNG2 as a molecular tether for conoid apical anchorage. Illustration of the consequences of RNG2 depletion on the apical complex structure of Toxoplasma gondii tachyzoites. Bottom: Toxoplasma gondii extracellular tachyzoite imaged through Ultrastructure-Expansion Microscopy and stained for tubulin (magenta ) and RNG2-mAID-HA (green). The original image has been modified for aesthetic purposes Credit : the data was produced by Romuald Haase and the image was designed by Albert Tell i Puig
The conoid is a structure in #Apicomplexans that extrudes during egress, gliding motility & invasion. This study shows that the coiled-coil protein RNG2 tethers the conoid to the apical polar ring in #Toxoplasma and is essential for invasion @plosbiology.org 🧪 plos.io/489blpq
Formation and dynamics of the plasma membrane reservoir (PMR). The PMR forms prior to the development of the daughter cells’ IMC. Its position and size vary during replication, and it is reabsorbed at the conclusion of daughter cell budding. We propose that the PMR facilitates the expansion of the PM surface during replication. All scale bars represent 1 µm. While the PMR is not always visible due to its transient nature, virtually all the parasites undergoing replication are forming a PMR.
How do #apicomplexans reorganize their #PlasmaMembrane (PM) while replicating inside host cells? This study shows that #Toxoplasma recycles its PM via Rab5b- & MyoF-dependent #endocytosis, linking PM reservoir formation to membrane homeostasis via the micropore @plosbiology.org 🧪 plos.io/46tDxny
Formation and dynamics of the plasma membrane reservoir (PMR). The PMR forms prior to the development of the daughter cells’ IMC. Its position and size vary during replication, and it is reabsorbed at the conclusion of daughter cell budding. We propose that the PMR facilitates the expansion of the PM surface during replication. All scale bars represent 1 µm. While the PMR is not always visible due to its transient nature, virtually all the parasites undergoing replication are forming a PMR.
How do #apicomplexans reorganize their #PlasmaMembrane (PM) while replicating inside host cells? This study shows that #Toxoplasma recycles its PM via Rab5b- & MyoF-dependent #endocytosis, linking PM reservoir formation to membrane homeostasis via the micropore @plosbiology.org 🧪 plos.io/46tDxny
Formation and dynamics of the plasma membrane reservoir (PMR). The PMR forms prior to the development of the daughter cells’ IMC. Its position and size vary during replication, and it is reabsorbed at the conclusion of daughter cell budding. We propose that the PMR facilitates the expansion of the PM surface during replication. All scale bars represent 1 µm. While the PMR is not always visible due to its transient nature, virtually all the parasites undergoing replication are forming a PMR.
How do #apicomplexans reorganize their #PlasmaMembrane (PM) while replicating inside host cells? This study shows that #Toxoplasma recycles its PM via Rab5b- & MyoF-dependent #endocytosis, linking PM reservoir formation to membrane homeostasis via the micropore @plosbiology.org 🧪 plos.io/46tDxny
Wow! So many nice drawings of protists! including #kinetoplastids #apicomplexans #alveolates #amebozoans
#Nephromyces encodes a urate #metabolism pathway and predicted #peroxisomes, demonstrating these are not ancient losses of #apicomplexans #symbiosis #evolution academic.oup.com/gbe/advance-article/doi/...
