#endocytosis RALF FER PI4P PI(4,5)P2 👌
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Hashtag
#endocytosis
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#Drosophila Abi maintains blood cell homeostasis by promoting clathrin-mediated #endocytosis of #Notch, say Hyun Gwan Park, Seungbok Lee and colleagues (Seoul National University): rupress.org/jcb/article/...
#CellSignaling #Development #Cytoskeleton
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In @jcb.org, Qiuyuan Yin, Chonglin Yang et al. reveal a plasma membrane-to-lysosome signaling pathway mediated by the non-receptor tyrosine kinase FGR and the serine/threonine kinase AKT2, which regulates TFEB/TFE3 activation for #lysosome biogenesis in #endocytosis. rupress.org/jcb/article/...
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Qiuyuan Yin, Chonglin Yang et al. reveal a plasma membrane-to-lysosome signaling pathway mediated by the non-receptor tyrosine kinase FGR and the serine/threonine kinase AKT2, which regulates TFEB/TFE3 activation for #lysosome biogenesis in #endocytosis. rupress.org/jcb/article/...
#Organelles
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🌟 Exo-Endo 2026 • May 27–29, Aussois (FR)
bit.ly/4oEmTHy
We’re excited to gather the membrane trafficking community, with a strong focus on young scientists!
📣 Registration mid-Feb. Stay tuned!!
#ExoEndo2026 #CellBiology #MembraneTrafficking #Endocytosis #Exocytosis #YoungScientists #EVs
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Hyun Gwan Park et al. show that #Drosophila Abi, a regulator of #actin cytoskeletal dynamics, controls blood cell homeostasis by activating #Notch signaling through #clathrin-mediated receptor #endocytosis. rupress.org/jcb/article/...
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🌟 Exo-Endo 2026 • May 27–29, Aussois (FR)
bit.ly/4oEmTHy
We’re excited to gather the membrane trafficking community, with a strong focus on young scientists!
📣 Registration mid-Feb. Stay tuned!!
#ExoEndo2026 #CellBiology #MembraneTrafficking #Endocytosis #Exocytosis #YoungScientists #EVs
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#endocytosis TPLATE complex
Great work by @danielvandamme.bsky.social
Roman pleskot and co-workers!
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Our Cell Membrane Structure & Transport model was top of the charts last week! Get hands-on to show facilitated #diffusion & co-transport, active transport by ATP, ion channels & bulk transport by #exocytosis & #endocytosis. Learn more here: buff.ly/ufu2jH6
#EduSky #iteachbio #activetransport
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Online now! EGFR, JNK & ROS signaling mediate bidirectional feedback between cyst cells and encapsulated germ cells in Drosophila testis. #germline #polarity #endocytosis #cellcommunication ow.ly/cK0o50Xeakc
@isscr.org @gairdnerawards.bsky.social @sickkidsvs.bsky.social @cellpress.bsky.social
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Slowing down to take it in: #Endocytosis during cellular #aging. Spotlight from Derek Prosser (Virginia Commonwealth University) on new work by Antenor, Usaj and colleagues (rupress.org/jcb/article/...): rupress.org/jcb/article/...
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Spotlight @jcb.org: Derek Prosser highlights new work from Antenor et al. (rupress.org/jcb/article/...), describing how elevated vacuolar pH in #aging yeast cells slows #clathrin-mediated #endocytosis. rupress.org/jcb/article/...
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Spotlight: Derek Prosser highlights new work from Antenor et al. (rupress.org/jcb/article/...), describing how elevated vacuolar pH in #aging yeast cells slows #clathrin-mediated #endocytosis. rupress.org/jcb/article/...
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Formation and dynamics of the plasma membrane reservoir (PMR). The PMR forms prior to the development of the daughter cells’ IMC. Its position and size vary during replication, and it is reabsorbed at the conclusion of daughter cell budding. We propose that the PMR facilitates the expansion of the PM surface during replication. All scale bars represent 1 µm. While the PMR is not always visible due to its transient nature, virtually all the parasites undergoing replication are forming a PMR.
How do #apicomplexans reorganize their #PlasmaMembrane (PM) while replicating inside host cells? This study shows that #Toxoplasma recycles its PM via Rab5b- & MyoF-dependent #endocytosis, linking PM reservoir formation to membrane homeostasis via the micropore @plosbiology.org 🧪 plos.io/46tDxny
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Vacuolar pH regulates #clathrin-mediated #endocytosis through #TORC1 signaling during replicative #aging, say Kenneth Gabriel Antenor, Mojca Mattiazzi Usaj et al. @torontometsci.bsky.social rupress.org/jcb/article/...
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Formation and dynamics of the plasma membrane reservoir (PMR). The PMR forms prior to the development of the daughter cells’ IMC. Its position and size vary during replication, and it is reabsorbed at the conclusion of daughter cell budding. We propose that the PMR facilitates the expansion of the PM surface during replication. All scale bars represent 1 µm. While the PMR is not always visible due to its transient nature, virtually all the parasites undergoing replication are forming a PMR.
How do #apicomplexans reorganize their #PlasmaMembrane (PM) while replicating inside host cells? This study shows that #Toxoplasma recycles its PM via Rab5b- & MyoF-dependent #endocytosis, linking PM reservoir formation to membrane homeostasis via the micropore @plosbiology.org 🧪 plos.io/46tDxny
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Formation and dynamics of the plasma membrane reservoir (PMR). The PMR forms prior to the development of the daughter cells’ IMC. Its position and size vary during replication, and it is reabsorbed at the conclusion of daughter cell budding. We propose that the PMR facilitates the expansion of the PM surface during replication. All scale bars represent 1 µm. While the PMR is not always visible due to its transient nature, virtually all the parasites undergoing replication are forming a PMR.
How do #apicomplexans reorganize their #PlasmaMembrane (PM) while replicating inside host cells? This study shows that #Toxoplasma recycles its PM via Rab5b- & MyoF-dependent #endocytosis, linking PM reservoir formation to membrane homeostasis via the micropore @plosbiology.org 🧪 plos.io/46tDxny
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In @jcb.org, Kenneth Gabriel Antenor, Mojca Mattiazzi Usaj et al. @torontometsci.bsky.social show that clathrin-mediated #endocytosis becomes less efficient in #aging yeast due to changes in vacuolar pH. rupress.org/jcb/article/...
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Kenneth Gabriel Antenor, Mojca Mattiazzi Usaj et al show that clathrin-mediated #endocytosis becomes less efficient in #aging yeast due to changes in vacuolar pH. Restoring pH or modulating TORC1-Npr1 signaling preserves endocytosis, which may help maintain cell function rupress.org/jcb/article/...
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Great teamwork with Stijn, Alexander, and Halim. 👏 Fruitful collaboration between Active Soft Matter Lab (www.activesoftmatter.nl) @utwente.bsky.social Halim's Lab @Univ. Edinburgh
#SoftMatter, #Biophysics, #Vesicles #Endocytosis #DrugDelivery #ActiveMatter
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Top: Cryo-EM map of the CD163/Hp(1–1)Hb complex colored by each component and shown in two side views and one bottom view. A map in transparent representation is contoured at a low level to show electron density for the unresolved flexible domain D1 and unbound HpHb protomer. Bottom: Cryo-EM map of the CD163/HpSPHb complex colored by each component and shown in two side views and one bottom view. A map in transparent representation is contoured at a low level to show electron density for the flexible peripheral regions.
The #macrophage CD163 receptor clears free #hemoglobin in the bloodstream by binding the HpHb complex. This #cryoEM structure of CD163-HpHb complex, by @chingshinhuang.bsky.social &co, reveals how CD163-mediated #endocytosis clears different HpHb isoforms @plosbiology.org 🧪 plos.io/4nNBbGI
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In #CElegans, the protein FLWR-1 helps manage calcium levels and vesicle recycling at the neuromuscular junction, challenging old models of its role in #endocytosis.
Video: Time series of a fluorescent particle travelling along commissures.
buff.ly/AUaZbSJ
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Thank you Matteo Bonazzi @irim-life.bsky.social
#infectiousdiseases #inflammation #cellbiology #autophagy #endocytosis #plasmamembrane #celladhesion
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Drs Narcisa Leal da Cunha-e-Silva, Carolina de Lima Alcantara, Miria Gomes Pereira & Wanderley De Souza review the efficient #endocytic pathway of pathogenic #trypanosomatids. #Endocytosis #Trypanosoma #brucei #cruzi #Leishmania #Cytostome #Reservosome
authors.elsevier.com/a/1lDSH5Eb1x...
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🚨 New review out!
We explore how extracellular acidification shapes key processes like endocytosis, neurotransmission & immune responses — and highlight tools to study it.
📖 Read more [https://doi.org/10.1016/j.ceb.2025.102531]
w/ amazing collaborators 🙌 #CellBiology #Endocytosis #GPCR
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This panel of images illustrates data supporting the report that Clathrin is required for DNA damage repair. Clockwise from upper left: Morphology and relative root lengths of sampled seedlings, GUS staining images of cotyledons, data representing relative HR efficiency, and confocal imaging of subcellular localization of CHC1 and CLC2.
In a new #FreeAccess Brief Communication, Yang et al. report on their identification of #clathrin as participating in the DNA damage response in plants
doi.org/10.1111/jipb...
#PlantScience #endocytosis 🔓
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Particle Metrix booth at the Congress of the Exocytosis-Endocytosis Club in Fort-Mahon
Bertrand Damart is at the 27th @clubexo-endo.bsky.social meeting.
Stop by the @particle-metrix.bsky.social booth to see how our #NTA technology can support your #EVResearch.
Don’t miss our talk on Wednesday at 11:15 a.m.!
exoendo.org/.../27th-con...
#exocytosis #endocytosis #EVs #ZetaView
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