Check out this review in #GENETICS from @gotworms.bsky.social, @cgc-worms.bsky.social, and others describing the first release in the Curated Special Collections for #Celegans, highlighting protein degradation systems and how to achieve targeted protein deletion in #nematode #worms. buff.ly/lEaf2T2
Congratulations to the legendary scientist Judith Kimble!!!
We stand on the shoulders of giants.
#womeninSTEM #celegans
In #GENETICS, @ravijanagal.bsky.social and @jogender-singh.bsky.social determine the role of RHY-1 as both a regulatory and effector component of the #hypoxia response pathway that mediates cellular protection against thiol reductive stress in #Celegans. buff.ly/81sTGYZ
⚒️ NEW TOOLBOX for #Celegans researchers 🪱
Theresa Gibney and Ariel Pani developed a method that allows for a standardized workflow to generate N-terminal and internal tags in any background and without the need for genetic balancers.
Paper in #GENETICS:🔗 buff.ly/wXMml3x
Figure 1
Caenorhabditis Intervention Testing Program: the anticonvulsant leviteracetam does not extend lifespan in nematodes. #micropublication #biology #data #caltechlibrary #Celegans #Caenorhabditisbriggsae micropublication.org/journals/biology/micropu...
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Swimming exercise during early-life starvation enhances adult stress resistance in Caenorhabditis elegans #micropublication #biology #data #caltechlibrary #Celegans #ModelsOfHumanDisease #NewFinding micropublication.org/journals/biology/micropu...
The 🆕 #omics report in the March issue of #G3journal presents #RNAseq and phenotypic analysis from multiple #Celegans mutant strains, which facilitates the dissection of genetic epistasis mechanisms in larval starvation resistance.🪱
🔗 Read the paper: buff.ly/uhXrEmX
It’s great to see our latest microPublication go live!
Four undergraduate researchers worked with grad student Kat Yamamoto to demonstrate a correlation between fat storage and survival of #Celegans on pathogenic bacteria!
Congrats Alan, Grace, Tiffany, and Daniel! #undergradinthelab #proudPI
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Suppression of the fat storage defect of C. elegans dbl-1/BMP signaling mutants correlates with improved survival on a bacterial pathogen #micropublication #biology #data #caltechlibrary #Celegans #Ph micropublication.org/journals/biology/micropu...
Stage-specific #transcriptomics of a leader cell reveals cell machineries driving collective invasion. New study from Priti Agarwal @pritiagarwal.bsky.social,
Ronen Zaidel-Bar and colleagues (Tel Aviv University): rupress.org/jcb/article/...
#Migration #Motility #Development #Trafficking #Celegans
Portrait of Gary B. Ruvkun with a quote on the significance of tiny RNA revolution in non-mammalian genetic research, featuring microscopic worm imagery.
Happy birthday to Gary B. Ruvkun! He became a #LaskerLaureate for discoveries that revealed an unanticipated world of tiny RNA that regulates gene function in plants and animals. 🧪🌱🪱 #RNAbiology #Celegans Harvard Medical School
Read more here: https://ow.ly/IfZL50YmFle
Representative immunostaining of anti-glutamylated tubulin (rMAb-GT335) in C. elegans hermaphrodites. Glutamylated tubulin is detected in labial and cephalic cilia (bracket) and the middle segments (MS) of amphid channel cilia. Scale bar=2μm.
Recombinant monoclonal antibodies to detect tubulin post-translational modifications work beautifully in #celegans neurons and cilia.
@kjverhey1.bsky.social shared ONE ML of each rMAb!
www.micropublication.org/journals/bio...
Blasius...Verhey 2025 Cytoskeleton: 10.1002/cm.70011. PMID: 40650552
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LIVEtools: an R Package for Visualizing C. elegans Embryo Cell Tracking Data #micropublication #biology #data #caltechlibrary #Celegans #Software #PhenotypeData #Methods #ImagingSoftware #ExpressionDa micropublication.org/journals/biology/micropu...
A new #GENETICS study from @katzlab.bsky.social, @bscarp84.bsky.social, and colleagues explores the relationships between histone modifications, nucleosome remodeling, and transcriptional repressors, which play an important role in maternal reprogramming in #Celegans. buff.ly/tHiFtAr
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Recombinant monoclonal antibodies for labeling tubulin post-translational modifications in Caenorhabditis elegans #micropublication #biology #data #caltechlibrary #Celegans #Biochemistry #ExpressionDa micropublication.org/journals/biology/micropu...
In #GENETICS, @uncnondpy.bsky.social et al. present a comprehensive mapping of genetic interactions among all #Celegans Wnt and its receptor genes, identifying how these interactions regulate the polarity of asymmetrically dividing stem cells. buff.ly/WIUus96
#Xenopus #Celegans #DevelopmentalBiology #ExperimentalModels #Organoids #AnimalCaps #Review
bsky.app/profile/nico...
List of posters and their titles presented by students
We are at #BonnBrain26!
Find us tomorrow at the poster session to chat about smelling delicious things and then eating them, and how what is delicious and what you eat may evolve! #celegans #worms #pharynx
New in #GENETICS: A systematic disruption of small RNA-binding capacity of multiple Argonaute proteins identifies a critical role of small RNA loading in maintaining the stability and localization of Argonaute proteins during #Celegans germline development. buff.ly/Aguq9c5
New research in #G3journal from Alexandre Schifano, Ulfar Bergthorsson, and @vaishalikatju.bsky.social identifies heteroplasmic structural variants of #mitochondrial DNA in #Celegans natural isolates, revealing different mutational spectra compared to laboratory strains. buff.ly/hWQ0FOr
RESEARCH PAPER: PHA-4/FoxA controls the function of pharyngeal and extrapharyngeal enteric neurons in C. elegans
By Walker et al., and Oliver Hobert
➡️ https://genesdev.cshlp.org/content/40/5-6/366.full
Columbia University HHMI
#transcriptionfactor #Celegans #neuron #gut
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Sex Alters Hypoxic Responses in Caenorhabditis elegans #micropublication #biology #data #caltechlibrary #Celegans #PhenotypeData #GeneModel #UndergraduateResearchExperience #NewFinding micropublication.org/journals/biology/micropu...
A new #omics report in #G3journal uses #RNAseq and phenotypic analysis to dissect the genetic epistasis mechanisms in #Celegans larval starvation resistance. buff.ly/xt3DjjU
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Characterization of the Immunoglobulin Domain of C. elegans SISS-1/EGF #micropublication #biology #data #caltechlibrary #Celegans #PhenotypeData #NewFinding micropublication.org/journals/biology/micropu...
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Bay leaf extract is a chemotaxis repellent for C. elegans #micropublication #biology #data #caltechlibrary #Celegans #UndergraduateResearchExperience #PhenotypeData #NewFinding micropublication.org/journals/biology/micropu...
Grateful to all our amazing co-authors for making this work possible!
#CellBiology #celegans #NuclearEnvelope #LipidMetabolism #OpenScience
The application form for #BSRA Summer Studentship is in! Wish me and Harrison good luck 🤞
#celegans #undergraduate #research #oxidativestress #parkinsonsdisease #CCCU
Congratulations to Irini Topalidou on her GSA Mentorship Award!
#celegans #womeninSTEM
@irinakitop.bsky.social
Congratulations to Judith Kimble on her Thomas Hunt Morgan Medal!
#celegans #womeninSTEM
