Care for some #toxoplasma with your beer? @colbertlateshow.bsky.social bear-poop-beer report is making toxoplasma great again
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#toxoplasma
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Fantastic talk of @sheinerlab.bsky.social today @pasteur.fr about these crazy ribosomal mitochondrial RNAs in #Toxoplasma!
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We look forward to seeing you all in Glasgow in April! (It is the week of Easter Monday, so please arrange travel with that in mind!). #parasitology #leishmania #ntds #universityofglasgow #parasites #mycology #trypanosoma #malaria #schistosoma #helminths #toxoplasma #cryptosporidium
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We look forward to seeing you all in Glasgow in April! (It is the week of Easter Monday, so please arrange travel with that in mind!).
#parasitology #leishmania #ntds #universityofglasgow #parasites #mycology #trypanosoma #malaria #schistosoma #helminths #toxoplasma #cryptosporidium
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🎶Ihre Welt aus Ordnung🎶
🎶Die ist mir zu steril🎶
🎶Und ihre Freiheit ist wie Stacheldraht🎶
#Toxoplasma - Asozial
#mussikmittwoch
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🎉 And to finish a great year… our latest paper is out!
We show that α-tubulin K40 acetylation is not essential for Toxoplasma gondii or Plasmodium berghei, highlighting the plasticity of parasite microtubule regulation.
#Apicomplexa #Toxoplasma #Plasmodium #Microtubules #CellBiology
Read it here:
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Científicos de la Universidad de Granada han diseñado un método pionero para detectar el #Toxoplasma gondii en la carne curada, un parásito que causa la toxoplasmosis
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🧪This 2018 Review has been cited more than 100 times (GoogleScholar):
Assessing viability and infectivity of #foodborne and waterborne stages (cysts/oocysts) of #Giardia duodenalis, #Cryptosporidium spp., and #Toxoplasma gondii: a review of #methods
doi.org/10.1051/para...
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"This interview with Dr. Emma H. Wilson details recent findings on how the chronic parasitic infection Toxoplasma gondii (*Toxo*) disrupts neurotransmission in the rodent brain. The study demonstrates ..."
www.youtube.com/watch?v=l6DP...
#Toxoplasma #Toxoplasmosis #Parasite #Parasitology
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Neue Konzertreview online: Generationenübergreifender Punkrock-Abend im Club „Das Bett“ mit der Deutschpunk-Legende #TOXOPLASMA um Sänger Wally Walldorf aus Neuwied und dem aufstrebenden Act N.T.Ä. aus dem Saarland bit.ly/44eWLvz #NTÄ #Punkrock
www.rockstage-riot-rheinmain.de/toxoplasma-n...
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Had a great time interviewing Dr. Lilach Sheiner (@sheinerlab.bsky.social) for the latest edition of ISOP’s Protistology Newsletter. Check it out here! #ProtistsOnSky #Toxoplasma #Science
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Campus del Jamón: Conferencia sobre el riesgo del parásito toxoplasma gondii asociado al consumo de jamón curado #Toxoplasma #JamónCurado #Nutrición #Bromatología #SaludPública
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Vanesa Abad, investigadora en el grupo NEOTEC, presenta el "Póster y Proyecto del mes", sobre la aplicación de los Pulsos Eléctricos de Alto Voltaje para la inactivación de parásitos como Anisakis spp. y Toxoplasma gondii. ¡Ven al Aulario o visita la web! #redantenasvetopen #anisakis #toxoplasma
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Bist Du geil auf Prügeln
Und wenns dein Hobby ist
Geh zur Polizei und werde Polizist
…
#Polizeistaat - wie damals '33
Das schönste an der Arbeit, du machst legal Rabatz
Dein warmer Gummiknüppel, das ist dein Schwanzersatz
#Toxoplasma kommentierten bereits 1983 unsere Gegenwart.
#Music #Punk
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![Top: Models for the spatial organization of the CIA pathway in T. gondii and related organisms. A sulfur-containing product of the mitochondrial ISC pathway (possibly a [2Fe-2S] cluster) is exported from the mitochondrion. [4Fe-4S] clusters assemble on the NBP35 scaffold (N35) at the mitochondrial outer membrane, with electrons for this process donated from NADPH via mitochondrial Tah18 (T18) and possibly Dre2 (D2). [4Fe-4S] clusters are transferred from the NBP35 scaffold to Nar1 (N1), and further to the CIA targeting complex (CTC) comprised of CIA1 (C1), CIA2 (C2) and MMS19 (M19). CIA1 contains an extended CD5 loop (green) that mediates localization of the entire CTC to the mitochondrion. The CD5 loop may bind to (i) outer mitochondrial membrane lipids or (ii) outer mitochondrial membrane accessory proteins, and place the CTC in position to receive FeS clusters from Nar1. Alternatively, (iii) the CD5 loop may mediate interactions with FeS client proteins that are anchored on the mitochondrial outer membrane, thus facilitating FeS transfer from the CTC to these proteins. Elements of the diagram were created in BioRender. Bottom: The CIA pathway localizes to the mitochondrion of Toxoplasma gondii. Immunofluorescence assays of TgTah18-HA and TgDre2-HA expressing parasites, probed with anti-HA antibodies (green) to label the proteins-of-interest and anti-TgTom40 antibodies (magenta) to label the mitochondrion. Scale bars are 2 µm.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:5522ztebtekoor5efelihqhb/bafkreifgajr3ojktnxypvgen6ebql7tg5ov3equvc6prgcio3tp3rhmi6m)
Top: Models for the spatial organization of the CIA pathway in T. gondii and related organisms. A sulfur-containing product of the mitochondrial ISC pathway (possibly a [2Fe-2S] cluster) is exported from the mitochondrion. [4Fe-4S] clusters assemble on the NBP35 scaffold (N35) at the mitochondrial outer membrane, with electrons for this process donated from NADPH via mitochondrial Tah18 (T18) and possibly Dre2 (D2). [4Fe-4S] clusters are transferred from the NBP35 scaffold to Nar1 (N1), and further to the CIA targeting complex (CTC) comprised of CIA1 (C1), CIA2 (C2) and MMS19 (M19). CIA1 contains an extended CD5 loop (green) that mediates localization of the entire CTC to the mitochondrion. The CD5 loop may bind to (i) outer mitochondrial membrane lipids or (ii) outer mitochondrial membrane accessory proteins, and place the CTC in position to receive FeS clusters from Nar1. Alternatively, (iii) the CD5 loop may mediate interactions with FeS client proteins that are anchored on the mitochondrial outer membrane, thus facilitating FeS transfer from the CTC to these proteins. Elements of the diagram were created in BioRender. Bottom: The CIA pathway localizes to the mitochondrion of Toxoplasma gondii. Immunofluorescence assays of TgTah18-HA and TgDre2-HA expressing parasites, probed with anti-HA antibodies (green) to label the proteins-of-interest and anti-TgTom40 antibodies (magenta) to label the mitochondrion. Scale bars are 2 µm.
Assembly of Fe-S clusters in the cytosol is an essential process in eukaryotic cells. This study shows that, unlike in other eukaryotes, this pathway takes place on the #mitochondrial outer surface in #Toxoplasma @plosbiology.org 🧪 plos.io/3KnjxL3
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Our new paper is out in Nature Communications! 🎉
We explore how Toxoplasma gondii organizes parasite development, combining cell biology and expansion microscopy to reveal new structural insights.
#Toxoplasma @meissnerlab.bsky.social @natcomms.nature.com
www.nature.com/articles/s41...
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Top: Models for the spatial organization of the CIA pathway in T. gondii and related organisms. A sulfur-containing product of the mitochondrial ISC pathway (possibly a [2Fe-2S] cluster) is exported from the mitochondrion. [4Fe-4S] clusters assemble on the NBP35 scaffold (N35) at the mitochondrial outer membrane, with electrons for this process donated from NADPH via mitochondrial Tah18 (T18) and possibly Dre2 (D2). [4Fe-4S] clusters are transferred from the NBP35 scaffold to Nar1 (N1), and further to the CIA targeting complex (CTC) comprised of CIA1 (C1), CIA2 (C2) and MMS19 (M19). CIA1 contains an extended CD5 loop (green) that mediates localization of the entire CTC to the mitochondrion. The CD5 loop may bind to (i) outer mitochondrial membrane lipids or (ii) outer mitochondrial membrane accessory proteins, and place the CTC in position to receive FeS clusters from Nar1. Alternatively, (iii) the CD5 loop may mediate interactions with FeS client proteins that are anchored on the mitochondrial outer membrane, thus facilitating FeS transfer from the CTC to these proteins. Elements of the diagram were created in BioRender. Bottom: The CIA pathway localizes to the mitochondrion of Toxoplasma gondii. Immunofluorescence assays of TgTah18-HA and TgDre2-HA expressing parasites, probed with anti-HA antibodies (green) to label the proteins-of-interest and anti-TgTom40 antibodies (magenta) to label the mitochondrion. Scale bars are 2 µm.
Assembly of Fe-S clusters in the cytosol is an essential process in eukaryotic cells. This study shows that, unlike in other eukaryotes, this pathway takes place on the #mitochondrial outer surface in #Toxoplasma @plosbiology.org 🧪 plos.io/3KnjxL3
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Top: Models for the spatial organization of the CIA pathway in T. gondii and related organisms. A sulfur-containing product of the mitochondrial ISC pathway (possibly a [2Fe-2S] cluster) is exported from the mitochondrion. [4Fe-4S] clusters assemble on the NBP35 scaffold (N35) at the mitochondrial outer membrane, with electrons for this process donated from NADPH via mitochondrial Tah18 (T18) and possibly Dre2 (D2). [4Fe-4S] clusters are transferred from the NBP35 scaffold to Nar1 (N1), and further to the CIA targeting complex (CTC) comprised of CIA1 (C1), CIA2 (C2) and MMS19 (M19). CIA1 contains an extended CD5 loop (green) that mediates localization of the entire CTC to the mitochondrion. The CD5 loop may bind to (i) outer mitochondrial membrane lipids or (ii) outer mitochondrial membrane accessory proteins, and place the CTC in position to receive FeS clusters from Nar1. Alternatively, (iii) the CD5 loop may mediate interactions with FeS client proteins that are anchored on the mitochondrial outer membrane, thus facilitating FeS transfer from the CTC to these proteins. Elements of the diagram were created in BioRender. Bottom: The CIA pathway localizes to the mitochondrion of Toxoplasma gondii. Immunofluorescence assays of TgTah18-HA and TgDre2-HA expressing parasites, probed with anti-HA antibodies (green) to label the proteins-of-interest and anti-TgTom40 antibodies (magenta) to label the mitochondrion. Scale bars are 2 µm.
Assembly of Fe-S clusters in the cytosol is an essential process in eukaryotic cells. This study shows that, unlike in other eukaryotes, this pathway takes place on the #mitochondrial outer surface in #Toxoplasma @plosbiology.org 🧪 plos.io/3KnjxL3
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🌟 BlueSky trending hashtags (1h):
#booksky #birds #books #poetry #art #photography #gamedev #digitalart #indiedev #furryart #sciart #furry #toxoplasma #apicomplexans #nature
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🔥 BlueSky trending hashtags (30m):
#booksky #birds #art #books #poetry #digitalart #photography #gamedev #indiedev #furryart #toxoplasma #apicomplexans #furry #sciart #thehollywoodhomeless
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🚀 BlueSky trending hashtags (15m):
#booksky #birds #books #poetry #art #digitalart #photography #gamedev #toxoplasma #apicomplexans #indiedev #furryart #thehollywoodhomeless #sciart #furry
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Top: Model RNG2 as a molecular tether for conoid apical anchorage. Illustration of the consequences of RNG2 depletion on the apical complex structure of Toxoplasma gondii tachyzoites. Bottom: Toxoplasma gondii extracellular tachyzoite imaged through Ultrastructure-Expansion Microscopy and stained for tubulin (magenta ) and RNG2-mAID-HA (green). The original image has been modified for aesthetic purposes Credit : the data was produced by Romuald Haase and the image was designed by Albert Tell i Puig
The conoid is a structure in #Apicomplexans that extrudes during egress, gliding motility & invasion. This study shows that the coiled-coil protein RNG2 tethers the conoid to the apical polar ring in #Toxoplasma and is essential for invasion @plosbiology.org 🧪 plos.io/489blpq
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Top: Model RNG2 as a molecular tether for conoid apical anchorage. Illustration of the consequences of RNG2 depletion on the apical complex structure of Toxoplasma gondii tachyzoites. Bottom: Toxoplasma gondii extracellular tachyzoite imaged through Ultrastructure-Expansion Microscopy and stained for tubulin (magenta ) and RNG2-mAID-HA (green). The original image has been modified for aesthetic purposes Credit : the data was produced by Romuald Haase and the image was designed by Albert Tell i Puig
The conoid is a structure in #Apicomplexans that extrudes during egress, gliding motility & invasion. This study shows that the coiled-coil protein RNG2 tethers the conoid to the apical polar ring in #Toxoplasma and is essential for invasion @plosbiology.org 🧪 plos.io/489blpq
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Top: Model RNG2 as a molecular tether for conoid apical anchorage. Illustration of the consequences of RNG2 depletion on the apical complex structure of Toxoplasma gondii tachyzoites. Bottom: Toxoplasma gondii extracellular tachyzoite imaged through Ultrastructure-Expansion Microscopy and stained for tubulin (magenta ) and RNG2-mAID-HA (green). The original image has been modified for aesthetic purposes Credit : the data was produced by Romuald Haase and the image was designed by Albert Tell i Puig
The conoid is a structure in #Apicomplexans that extrudes during egress, gliding motility & invasion. This study shows that the coiled-coil protein RNG2 tethers the conoid to the apical polar ring in #Toxoplasma and is essential for invasion @plosbiology.org 🧪 plos.io/489blpq
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a colorful graphic showing presence and absence of various genes across the diversity of eukaryotes
New #ISEPpapers! Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in Toxoplasma rupress.org/jcb/article/...
#Toxoplasma #Protists #Parasites #Microbes #Golgi #Evolution
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Calling #Hawaii residents! The University of Hawaii at Manoa School of Medicine is seeking volunteers to donate a teaspoon of blood to test for #Toxoplasma gondii. You will be compensated for your time. If interested, contact Dr. Jerrisa Ching Choe (jching21@hawaii.edu).
#OneHealth
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Primera investigación a largo plazo sobre la exposición a #toxoplasma en #rumiantes silvestres de los Pirineos
@creaf.cat @uab.cat
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ACHTUNG: Wir verlosen 2 x 2 Tickets für die Show der Punk-Institution TOXOPLASMA aus Neuwied mit Support von N.T.Ä. aus Saarbrücken am 28.11.2025 im Frankfurter Club 'Das Bett'. Alle Infos: bit.ly/49TThSH #Toxoplasma #NTÄ #Punk #Verlosung #Gewinnspiel
www.rockstage-riot-rheinmain.de/freitickets-...
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New on bioRxiv!
Our manuscript shows how the methyltransferase PCKMT primes the conoid by retaining Formin1 for motility initiation in Toxoplasma gondii, working with AKMT to activate the parasite’s motility machinery.
#Toxoplasma #Apicomplexa #Methylation #ParasiteMotility
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