Beautiful #preprint on a novel regulator of plant #autophagy from the @cnaumann123.bsky.social lab. How do plants regulate #autophagosome size??? ER-PM contact sites and Can1 seem to be key! www.biorxiv.org/content/10.6...

🎥 The Keystone Symposium on Autophagosomes & Endolysosomes is now on demand!

Watch talks on lysosome‑mediated quality control, nutrient regulation & cell signaling—insights from leaders in the field
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👉 keysym.us/KSAutophagy2...
#KSAutophagy25 #autophagosome #endolysosomes @bealelab.bsky.social

LRBA deficiency impairs autophagy and contributes to enhanced antigen presentation and T-cell dysregulation | EMBO reports imageimageLRBA regulates autophagy and antigen presentation, shedding light on the mechanism of immune dysregulation in LRBA deficiency. LRBA directly interacts with PIK3R4 and FYCO1, promoting autop...

LRBA interacts with PIK3R4 and FYCO1, promoting #autophagosome formation, and fusion with lysosomes. Defective cargo degradation in LRBA-deficient cells , enhances #antigen presentation and #T-cell driven proinflammatory cytokine production.

www.embopress.org/doi/full/10....

Join us at Autophagosomes & Endolysosomes! Submit your abstract for a poster presentation by June 4. There's a cash prize for the top poster, presented by Autophagy and Autophagy Reports! keysym.us/KSAutophagy25

#KSAutophagy25 #autophagosome youtu.be/qyYWMQYpjFQ
@tandfresearch.bsky.social

Submit your abstracts/scholarship applications by 3/27 (11:59pm MST) to present at the Autophagosomes and Endolysosomes meeting. Join Christina Towers & other leading experts! Dive in: keysym.us/KSAutophagy25.

#KSAutophagy25 #autophagosome #endolysosomes youtu.be/zTfeKZSGF9Y @bealelab.bsky.social