#badglycans

#badglycans #glycotime

Snapshot of a highly distorted sialic acid 'docked' onto Asn612 in the binding site of a protein. All rendered in sticks

#badglycans sialylated Asn 😱😱

"These data suggests that inhibition of ACO2 activity, through sialylation of Asn 612, is because of major distorsions of the active site..."

Pls revise to:

"This figure and conclusions suggest that none of the reviewers read the manuscript"

How do we better improve communication that there is a single, agreed upon, worldwide nomenclature, SNFG?
It would help prevent #badglycans such as these.
www.ncbi.nlm.nih.gov/glycans/snfg...

An example of #badglycans
Yellow glucose!

www.sciencedirect.com/science/arti...

PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Now published in PNAS, this is a fantastic paper on how HA moves within a virion upon receptor binding. By the way, do check the #badglycans in Figure 6 😐
www.pnas.org/doi/10.1073/...

Fig 1 panel a) showing 3 glucoses topping the Man9GlcNAc2 as pink-ish triangles, def not SNFG-compliant

Reported by a colleague, the glyco-🚓 never rests, especially when triangles are used for the wrong sugar!! 😱😱 #badglycans

www.nature.com/articles/s41...

New entry for #badGlycans.
Even MS vendors aren’t safe!

Identification of a broad-inhibition influenza neuraminidase antibody from pre-existing memory B cells Identifying broadly reactive B precursor cells and conserved epitopes is crucial for developing a universal flu vaccine. In this study, using influenz…

Happy new year all... look what i just found in the graphical abstract... #badglycans
www.sciencedirect.com/science/arti...