Bone substitutes [:fr]Principe de l'antibiothérapie localeAu cours des IOA, les antibiotiques sont utilisés par voie "systémique" c'est à dire par voie orale ou par voie intraveineuse. Seule une petite proportio

Antibiotic-loaded #bonesubstitutes (i) act as a carrier to deliver locally high concentrations of antibiotic that have strong local antibacterial effects ; and (ii) provide a biological setting that promotes bone regeneration.

crioac-lyon.fr/en/substituts-…

Thanks to 9th EKMUD for let me presenting innovative options in bone and joint infections such as #phages and antibiotic-loaded #bonesubstitutes that can salvage patients from amputation: here #cerament with genta and vanco ➡️ local combination to treat and prevent superinfection

Frontiers | Innovative Approaches In The Management Of Bone and Joint Infection Bone and joint infections (BJI) are one of the most difficult-to-treat bacterial infectious diseases. Its management is complex, and requires a multidiscipli...

As a topic editors @FrontiersIn we believe that the next years will be pivotal to change the burden of bone and joint infections, especially #pji and #osteomyelitis, with #phages or innovative #bonesubstitutes or #cement ➡️ submit in this research topic!

frontiersin.org/research-topic…

What are alternatives for patients with chronic #BJI? As discussed last month during my talk at #ECCMID2019, many options are emergent to preserve the function: #bonesubstitutes, subcutaneous antibiotics, #antipersisters, GMP #bacteriophages and promising #bacteriophagelysins!