Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals The segregation of glycosylphosphatidylinositol-anchored proteins (GPI-APs) to distinct domains on the plasma membrane of eukaryotic cells is importan…

If you assume GPI insertion signals = surface destination, trypanosomes disagree.

Tom’s work shows GPI-anchored protein sorting occurs independently of GPI insertion signals, hinting at alternative sorting logic at the parasite surface.

tinyurl.com/gpi-anchor
#MembraneBiology #CellSurface

Come work with us! IPI is seeking a #postdoctoralfellow to join us and apply our #antibodydiscovery platforms to cutting-edge questions in #cellsurface #proteinresearch and #antibodyengineering. It could be you!

Learn how to apply today: buff.ly/f2cLV4D

Could boosting this molecule slow pancreatic cancer progression? – BioNews Central Scientists have discovered a cell surface sugar that slows pancreatic cancer in mice and is detectable in patient blood samples. ...

Scientists have discovered a #CellSurface #sugar that slows #PancreaticCancer in mice and is detectable in patient blood samples.
#PancreaticDuctalAdenoCarcinoma #TherapeuticTarget #Biomarker

🦠The #cellsurface is a hub of complex interactions where proteins, molecules & cells communicate.

Join experts at Janelia to explore the latest research shaping our understanding of this critical interface.

Registration, hotel & meals covered.

🗓️ Apply by May 20 @ janelia.news/SRF25
@hhmi.org

The 2nd talk at #EFMCISCB was from @berndwollscheid.bsky.social from @ethzurich.bsky.social who shared his labs work on #cellsurface capture technology using #chemoproteomics. insight into cell type-specific proteins, monitoring ligand-receptor affinity, spatial distribution of complexes! #chembiol