WP3 | Engineering Antibodies for Imaging and Therapy

To know more about the project: abcardionostics.eu

#EUproject #EUfunded #EICPathfinder #CradiovascularHealth #AntibodyEngineering

Nuclera extends Series C funding to advance antibody engineering - PharmaTimes Investment to accelerate development of full‑format antibody capabilities on eProtein Discovery system

#biologicsdiscovery #drugdiscovery #Nuclera #SeriesCfunding #antibodyengineering #eProteinDiscoverysystem #eProteinDiscovery #AIenabledproteinengineering #biologicsdiscovery #membraneproteinworkflow #Cytiva #DNA #Domainex #CROimplementation #biologicsRandD
zurl.co/lO4B9

Apply to the Springer-Lu Postdoctoral Fellowship to secure a place at IPI and 2+ years of funding to pursue ambitious research in #proteinresearch and #antibodyengineering.

Applications close in one week on Jan. 20: buff.ly/CCEOKjO

#PostDocJobs #PostDocPosition #PhDChat #ScienceJobs #STEMCareers

🤩 Wow #AET2025, what a turnout!

Thanks to everyone who packed the house to hear Colby Souders’ talk “Scaling Machine Learning in Biologics: Leveraging High-Throughput Data for Next-Gen Biotherapeutic Discovery.”

@twistbioscience.com #AntibodyEngineering

Engineering tandem VHHs to target different epitopes to enhance antibody-dependent cell-mediated cytotoxicity

buff.ly/5kQgJMH

#AntibodyEngineering #VHH #ADCC

Springer-Lu Postdoctoral Fellowship

This is great, thank you @owoolnough.bsky.social! We're looking for a postdoctoral fellow in #cellsurfaceproteinresearch & #antibodyengineering, and would love to see some applicants who overlap with our #Neuroscience Program! We'll be sure to add #NeuroJobs in the future! shorturl.at/HHWqK

MiXCR powered BCR extraction in this study, and with Platforma you can now go further—model structure, predict binding affinity, and rank top antibody leads by developability.

Learn more here: platforma.bio/antibody-dis...

#antibody #antibodydiscovery #antibodyengineering

Come work with us! IPI is seeking a #postdoctoralfellow to join us and apply our #antibodydiscovery platforms to cutting-edge questions in #cellsurface #proteinresearch and #antibodyengineering. It could be you!

Learn how to apply today: buff.ly/f2cLV4D

DNA and jolts of electricity get people to make optimal antibodies One of the things that emerging diseases, including the COVID and Zika pandemics, have taught us is that it’s tough to keep up with infectious diseases in the modern world. Things like air travel can...

DNA and jolts of electricity get people to make optimal antibodies #Science #Biology #MolecularBiology #Biotechnology #AntibodyEngineering #GeneticResearch

Replacement of a single residue in an antibody abolishes cognate antigen binding, as predicted by theoretical methods. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.018

🔗 Replacement of a single residue in an antibody abolishes cognate antigen binding, as predicted by theoretical methods. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#AntibodyEngineering #StructuralBiology #ProteinModeling #Biophysics #FTIR

Computational nanobody design through deep generative modeling and epitope landscape profiling. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.07.052

🤖 Can algorithms outsmart evolution to create therapies humans never imagined?

🔗 Computational nanobody design through deep generative modeling and epitope landscape profiling. DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#AntibodyEngineering #Nanobody #ProteinDesign #DrugDiscovery @csbj.org

Next generation of multispecific antibody engineering Statement of Significance: Multispecific antibodies hold immense potential in addressing unmet medical needs unachievable by monoclonal antibodies, yet the

This article, published last year, has already been cited 30 times, and downloaded over 21,000 times!

Many thanks to the authors from Gilead!

#AntibodyEngineering #MultiSpecific

doi.org/10.1093/abt/...

Together with the first structural information on a monoclonal antibody bound to a key female #fertilization protein, this paves the way to the development of targeted non-hormonal #contraceptives

#StructuralBiology #ReproductiveBiology #AntibodyEngineering #NonHormonalContraception

From Assay to Algorithm: A Scientist’s Perspective on What’s Worth Watching A scientist’s guide to high-throughput screening, phenotypic assays, antibody discovery, and cutting-edge drug development tools

I started a Medium series on tools and technologies in drug discovery, especially antibody development, screening, and MoA assays. I’ll be breaking down papers that offer something useful (or not).

Intro: medium.com/@enginyapici...

#DrugDiscovery #AntibodyEngineering #Bioassays #MoA #Biotech

Engineering Antibodies with a Novel Fusion Protein A novel fusion protein designed by researchers boosts antibody generation against complex targets—reshaping diagnostics and therapeutics.

Discover how a novel fusion protein is transforming antibody engineering, paving the way for groundbreaking therapies. #AntibodyEngineering #DrugDiscovery #BiomedicalResearch

Four years after AlphaFold's AI ‘solved’ protein structure, a fierce competition lives on AlphaFold solved a structural biology riddle: predicting protein structure. And yet, CASP, a global competition born to solve that problem, lives on.

Is #AI in #antibodyengineering all hype? About to put #experimentalists out of business? Great insights in @statnews.com earlier this month, including words from Andrew Bradbury at Specifica ⬇️

Redirecting

I am happy to share our latest review, which discusses the challenges of predicting unbound antibody structures using deep learning. Special thanks to Alexander Greenshields-Watson for leading and coordinating this work! 🧬💻
doi.org/10.1016/j.sb...

#AntibodyEngineering #DeepLearning

We’ll soon be #hiring #postdoc researchers and #PhD students in #super-resolution #microscopy, #cryoEM, #AntibodyEngineering, and #proteindesign.

Please get in contact if you're interested!

@bristolbiodesign.bsky.social #ERCconsolidator #immunology #cryoET #biochemistry

Talks also delved into #AntibodyEngineering by Dr. Janet Peper-Gabriel (Plectonic Biotech), immune #CellEngineering by Dr. Anke Fuchs (TU Dresden), and #TissueEngineering innovations by Prof. Michael Raghunath (Zurich University of Applied Sciences).