🔬 Choosing the right cellular deconvolution tool is key!
With so many options, it’s crucial to match your tool to your needs!
Read our blog to help you choose wisely! www.fiosgenomics.com/tool-selection-for-cellu...
#Bioinformatics #RNAseq #Deconvolution #ComputationalBiology
"Wissen über das Eingangssignal ist notwendig,
für die Lösung des Problems."
#Reiche dient
der #Bereicherung von Individuen
einer ausbeuterischen Ölindustrie
und nicht dem deutschen Volk! 🇩🇪
Zitat aus
Anton Ziolkowski: #Deconvolution (Boston: IHRDC, 1984)
[einem Grundlagenwerk zum Fracking von Öl]
🧬 #Bioinformatics: In RNA sequencing of tissue samples, researchers measure how much #RNA from a gene is present in the sample as a whole. So-called #deconvolution methods then try to infer the cellular composition from these measurements. A team from Innsbruck and Munich has now developed […]
🧬 #Bioinformatik: Bei der RNA-Sequenzierung von Gewebeproben misst man, wie viel #RNA eines Gens in der gesamten Probe vorkommt. Mit sogenannten #Deconvolution-Verfahren versucht man dann, aus den Messdaten die Zell-Zusammensetzung zu berechnen. Ein Team von Uni Innsbruck & TU München […]
🔬 Choosing the right cellular deconvolution tool is key!
With so many options, it’s crucial to match your tool to your needs!
Read our blog to help you choose wisely! www.fiosgenomics.com/tool-selection-for-cellu...
#Bioinformatics #RNAseq #Deconvolution #ComputationalBiology
🔬 Choosing the right cellular deconvolution tool is key!
With so many options, it’s crucial to match your tool to your needs!
Read our blog to help you choose wisely! www.fiosgenomics.com/tool-selection-for-cellu...
#Bioinformatics #RNAseq #Deconvolution #ComputationalBiology
Microscopists! Do you encounter stitching in your work? Join our free online WEBINAR on Jan. 27th (you can also get a free trial!), and explore all the solutions that we offer for problematic stitching.
More info: svi.nl/webinarschedule
#vignettingcorrection #deconvolution #microscopy #lightsheet
🔬 Choosing the right cellular deconvolution tool is key!
With so many options, it’s crucial to match your tool to your needs!
Read our blog to help you choose wisely! www.fiosgenomics.com/tool-selection-for-cellu...
#Bioinformatics #RNAseq #Deconvolution #ComputationalBiology
On Day 5 of AQLM, we dive into #deconvolution with Sid Shaw (Indiana Univ.) and then follow that up with everyone's favorite #confocal #imaging of EB1 dynamics in Arabidopsis!
If you want to learn to be a great microscopist, apply attend in 2026 bit.ly/49YQl7q
Dear Imaging Experts: participate in this year's Huygens #Microscopy Image Contest with your most beautiful images and movies and win a laptop or SSD with a microscope image! See this website on how to participate: svi.nl/ImageContest
#ScienceArt #Microscopy #deconvolution #imageanalysis
To refine habenula signal from neighboring thalamus we utilized our #snRNAseq data to perform #deconvolution on our bulk samples, estimating proportion of habenula. These proportions were used to control for dissection differences in the differential expression analysis
🔬 Choosing the right cellular deconvolution tool is key!
With so many options, it’s crucial to match your tool to your needs!
Read our blog to help you choose wisely! www.fiosgenomics.com/tool-selection-for-cellu...
#Bioinformatics #RNAseq #Deconvolution #ComputationalBiology
A Wormhole in our Universe?
Animation of a curled up C. elegans nematode imaged with a spinning disk confocal, deconvolved and rendered using the Huygens Software. C/o Igor Bonacossa Pereira, Hilliard Lab, Queensland Brain Institute.
#Neuroscience #microscopy #deconvolution #imageanalysis
Artefact-free #deconvolution with abberior’s #TRUESHARP image boosting. Confocal image of the #Drosophila embryo CNS stained for tubulin (🟦STAR ORANGE) and DNA (🟩PicoGreen).
TRUESHARP is also available as a free online tool: link.abberior.rocks/true
#fluorescencefriday
And even more surprise, pH-dependent response is independent of well-known pH sensors in macrophages. To understand better how it happens, we developed a #deconvolution model to quantify how pH and immune signals interact to activate each gene.
Alert 🔥 A computational pipeline will be online soon.
🧬🖥️🧪 Interested in single-cell-informed cell-type #deconvolution? Have a look at our enhanced benchmarking study and #omnideconv ecosystem!
www.biorxiv.org/content/10.1...
Standard #deconvolution relies on a-priori assumptions that may artifacts.
#TRUESHARP image boosting is better:
It incorporates measured information from the image to reliably remove noise and background & enhance resolution without falsification.
Test the free online tool here: app.truesharp.rocks
Wow. Image processing of tiled image volumes as large as 1 cm3, and acquired with a widefield setup!
Congratulations to all authors for getting now to the reviewing stage. Happy to have made a small contribution.
#microscopy #imaging #deconvolution
New preprint out: Depth-Variant Deconvolution Applied to Widefield Microscopy for Rapid Large-Volume Tissue Imaging
👉 www.researchgate.net/publication/...
#Microscopy #BioImaging #WidefieldMicroscopy #Deconvolution #3DImaging #TissueImaging #LifeSciences #ADAPT3D #OpenScience
The new freedom of image boosting:
our #TRUESHARP online #deconvolution at app.truesharp.rocks!
1) open your image
2) adjust decon settings with just 4 sliders
3) enjoy intelligent image processing on your local device
And yes, there is no need for registration and no fee 😊
🚀Going deeper, we demonstrate that #deconvolution is now a multi-modal data integration technique with most frameworks using #singlecell data, #spatial coordinates or tissue image. We delineate the diversity of approaches to integrate these data types.
We first present the overall workflow of cell-type #deconvolution for #spatialtranscriptomics from input to output. We highlight a first dichotomy between methods depending on wether they use #singlecell data and also pinpoint the novel use of tissue image as a new modality.
#TRUESHARP image boosting is available as a lean online tool – no cost, no registration, nothing but pure processing bliss! app.truesharp.rocks
Just open your tiff image and enjoy effortless noise reduction, background clearance, and resolution enhancement. Test TRUESHARP #deconvolution right away!
This paper was an exciting culmination of a lots of exploration with #deconvolution ! Check-out my blog post on this work for the TL;DR version: lahuuki.github.io/posts/2025-0...
We ran #deconvolution on the 110 bulk RNA-seq samples, with six selected methods: #DWLS, #bisqueRNA, #MuSiC, #BayesPrism, #hspe, and #CIBERSORTx. The methods returned a wide range of proportion estimates 📊
Testing these #deconvolution methods was made possible by a really cool multi-assay dataset from consecutive slices of #DLPFC tissue blocks 🧠1. Bulk RNA-seq 🧬 2. #snRNAseq as the reference 🦠 3. #RNAScope serving as a orthogonal measurement of cell type proportions 🔬
This #deconvolution project was a group effort! Thanks to the whole team including: @shkwon-bcmbneuro.bsky.social @nick-eagles.bsky.social @daiannaglez.bsky.social @metamaden.bsky.social @stephaniehicks.bsky.social @kr-maynard.bsky.social @lcolladotor.bsky.social
Hey #deconvolution fans! 👀 We’ve got an exciting new publication for you: a benchmark of 6 popular deconvolution methods on a multimodal human brain #DLPFC dataset 🧠🧬
Now out in Genome Biology: doi.org/10.1186/s130...
@lieberinstitute.bsky.social @jhubiostat.bsky.social
🔬 Choosing the right cellular deconvolution tool is key!
With so many options, it’s crucial to match your tool to your needs!
Read our blog to help you choose wisely! www.fiosgenomics.com/tool-selecti...
#Bioinformatics #RNAseq #Deconvolution #ComputationalBiology
Hello everyone,
I am pleased to announce a new paper and a new software package: NFdeconvolve! 🎉🎉🎉🎉🎉🎉🎉🎉🎉🎉
📄 ArXiv – arxiv.org/abs/2501.08288
🛠️ GitHub – github.com/PessoaP/NFde...
Follow the🧵
#datascience #MachineLearning #NormalizingFlows #Deconvolution #SignalProcessing #statistics #python
