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Researchers Develop Externally Validated Prognostic Model for Newly Diagnosed Follicular Lymphoma Researchers determined the FLIPI24 prognostic model performs excellently in cases of newly diagnosed follicular lymphoma.

The FLIPI24 prognostic model performs excellently in cases of newly diagnosed #follicularLymphoma, demonstrating superiority over existing models. Published in @ascopost.bsky.social.

https://bit.ly/4uTbTuo

#lymsm

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SWOG SOO16: CHOP-Based Chemoimmunotherapy Achieves Cure in Certain Advanced-Stage Follicular Lymphoma Patients Investigators analyzed OS and PFS for patients with follicular lymphoma following chemoimmunotherapy with cyclophosphamide, hydroxydaunorubicin/doxorubicin, oncovin, and prednisone/ prednisolone (CHOP)–based regimens at 15 years.

After 15 years of follow-up, a “substantial subset” of patients with previously untreated advanced #follicularLymphoma achieved cure with CHOP-based chemoimmunotherapy. Published in @jamaoncology.com and @cancertherapyadv.bsky.social.

https://bit.ly/46TSlM0

#lymsm

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Pirtobrutinib Safe and Effective in Relapsed/Refractory Follicular Lymphoma Researchers determined pirtobrutinib was effective and well-tolerated among a cohort of patients with heavily pretreated relapsed/refractory follicular lymphoma.

Pirtobrutinib was effective and well-tolerated among a cohort of patients with heavily pretreated R/R #follicularLymphoma. Published in @bloodjournals.hematology.org.

https://bit.ly/4lnz63e

#lymsm

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Figure 1. Survival Curves with three graphs: A) overall vs progression-free survival, B) overall survival, and C) progression-free survival. Each shows survival percentages over 20 years post-randomization, comparing 'R-CHOP' and 'CHOP-RIT' treatments.

Figure 1. Survival Curves with three graphs: A) overall vs progression-free survival, B) overall survival, and C) progression-free survival. Each shows survival percentages over 20 years post-randomization, comparing 'R-CHOP' and 'CHOP-RIT' treatments.

Fifteen-year follow-up of the SWOG S0016 trial demonstrates that 42% of patients with advanced-stage #FollicularLymphoma treated with CHOP-based chemoimmunotherapy achieve functional cure.

ja.ma/4s6Fm1F

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Epcoritamab Plus Rituximab Effective in High-Tumor-Burden Follicular Lymphoma - Oncology Nurse Advisor In this phase 2 study, researchers sought to determine whether cytoreductive treatment with rituximab followed by epcoritamab would deepen responses and lower risk of cytokine release syndrome.

Treatment with rituximab plus epcoritamab achieves rapid and deep responses in #follicularLymphoma patients with a high tumor burden, with a 1-year progression-free survival rate of more than 95%. From @cancertherapyadv.bsky.social.

https://bit.ly/49dK3Pd

#lymsm

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Lunsumio Velo Approved for SC Administration in R/R Follicular Lymphoma FDA grants accelerated approval to subcutaneous mosunetuzumab-axgb for adults with relapsed or refractory follicular lymphoma after 2 therapy lines.

The @fda.gov has granted accelerated approval to Lunsumio Velo™, a SC formulation of mosunetuzumab-axgb, for the treatment of adult patients with R/R #follicularLymphoma after 2 or more lines of systemic therapy. From @medicalprofref.bsky.social.

https://bit.ly/4qoYAP8

#lymsm

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Compared with #obinutuzumab monotherapy, the next-gen BTK inhibitor #zanubrutinib in combination with #obinutuzumab led to improved survival in patients with #FollicularLymphoma, resulting in ORRs of 70.3% vs. 44.4% and PFS of 22.1 vs. 10.3 months: https://ow.ly/qzV250XMMvj
#HemeSky #MedSky

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Tafasitamab Plus Lenalidomide and Rituximab Nets European Approval in R/R Follicular Lymphoma | OncLive Tafasitamab plus lenalidomide and rituximab has been approved by the European Commission in relapsed/refractory follicular lymphoma.

Tafasitamab Plus Lenalidomide and Rituximab Nets #EuropeanApproval in R/R #FollicularLymphoma

www.onclive.com/view/tafasit...

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🔗 Read more: bit.ly/ONCOnews18D-02

#ONCOnews #OncoAlert #OncEd #OncologyNews #EUApproval #FollicularLymphoma #Hematology

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Epcoritamab reduced the risk for death by 79%. Presented at #ASH25, by Dr Falchi of @mskcancercenter.bsky.social covered by @cancertherapyadv.bsky.social.

https://bit.ly/4q4fQcb

#lymsm #follicularLymphoma

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Epcoritamab Triplet Boosts Outcomes in Relapsed/Refractory Follicular Lymphoma Epcoritamb plus lenalidomide and rituximab improves PFS and complete response in patients with relapsed/refractory follicular lymphoma in second line compared with lenalidomide and rituximab alone.

Interim data from the phase 3 EPCORE FL-1 trial suggests that adding the CD3xCD20 bispecific antibody epcoritamab to lenalidomide plus rituximab markedly improves response rates and PFS in R/R #follicularLymphoma. Presented at #ASH25.

https://bit.ly/3KndbLP

#lymsm

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Epcoritamab Plus Rituximab Effective in High-Tumor-Burden Follicular Lymphoma Treatment with rituximab plus epcoritamab has achieved rapid and deep responses in follicular lymphoma patients with a high tumor burden.

Treatment with rituximab plus epcoritamab achieves rapid and deep responses in #follicularLymphoma patients with a high #tumor burden, with a 1-year progression-free survival rate of more than 95%. Presented by Reid Merryman, MD of @danafarber.bsky.social.

https://bit.ly/4aB6sbA

#lymsm

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In patients with #follicularLymphoma being treated in the third-line setting or later, liso-cel therapy is associated with durable responses. Presented at #ASH25 by Sairah Ahmed, MD from @mdanderson.bsky.social

https://bit.ly/44aFe7Y

#lymsm

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IRF4 Promotes Immune Evasion and Shapes the Tumor Microenvironment in Follicular Lymphoma Elevated IRF4 expression in follicular lymphoma cells may contribute to immune evasion and aggressive disease features by impairing B-cell antigen presentation, altering cytokine signaling, and…

New in Blood Cancer Discovery: IRF4 Shapes the #Lymphoma TME buff.ly/7wbtXW8

Elevated IRF4 expression in #follicularlymphoma cells may contribute to immune evasion and aggressive disease features by impairing B-cell antigen presentation, altering cytokine signaling, and rewiring metabolism.

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RocheのLunsumio皮下注製剤、再発・難治性濾胞性リンパ腫に対しEUで条件付き承認 外来投与が約1分に短縮 | STELLANEWS.LIFE Rocheは、再発または難治性濾胞性リンパ腫に対するLunsumio(mosunetuzumab)皮下注製剤が欧州委員会より条件付き販売承認を取得したと発表。投与時間の短縮や有効性、安全性が第1/2相試験で確認され、外来投与の利便性向上に寄与。

Roche’s Lunsumio SC Granted Conditional EU Approval for Relapsed/Refractory Follicular Lymphoma

🔗 Full article: stellanews.life/technology_c...

#Roche #Lunsumio #Mosunetuzumab #FollicularLymphoma #Hematology #CancerTherapy #Subcutaneous #OncologyNews #Biopharma

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Approvals extend use of Roche, AbbVie drugs in lymphoma Patients in the US and EU with follicular lymphoma have new treatment options, thanks to new approvals for CD20xCD3 bispecifics Lunsumio and Epkinly.

Patients in the #US and #EU with #follicularlymphoma (FL) have new treatment options, thanks to #regulatoryapprovals for #Roche's Lunsumio and #AbbVie/Genmab's Epkinly.

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#Lymphopoiesiscont36
#NonHodgkinsLymphoma  #BurkittLymphoma #FollicularLymphoma #MantleCellLymphoma #MarginalZoneLymphoma #DiffuseLargeBCellLymphoma #PrimaryCNSLymphoma #BCellLymphoma #LymphomaAwareness #Oncology #CancerEducation #MedicalNotes #Hematology #ChromosomalTranslocation #GeneticMutations #MedicalInfographic #Histopathology #MedicalLearning #MedStudent #Pathology

#Lymphopoiesiscont36 #NonHodgkinsLymphoma #BurkittLymphoma #FollicularLymphoma #MantleCellLymphoma #MarginalZoneLymphoma #DiffuseLargeBCellLymphoma #PrimaryCNSLymphoma #BCellLymphoma #LymphomaAwareness #Oncology #CancerEducation #MedicalNotes #Hematology #ChromosomalTranslocation #GeneticMutations #MedicalInfographic #Histopathology #MedicalLearning #MedStudent #Pathology

#Lymphopoiesiscont36
#NonHodgkinsLymphoma #BurkittLymphoma #FollicularLymphoma #MantleCellLymphoma #MarginalZoneLymphoma #DiffuseLargeBCellLymphoma #PrimaryCNSLymphoma #BCellLymphoma #LymphomaAwareness #Oncology #CancerEducation #MedicalNotes #Hematology #ChromosomalTranslocation #GeneticMutations

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Recently, Gottfried von Keudell shared the long-term follow-up results from the Phase II ELM-2 study evaluating the efficacy of the bispecific antibody odronextamab in patients with R/R #FollicularLymphoma.

Watch here:

👉 buff.ly/6GUNfkY 👈

#ImmunoOnc #LYMsm #CTSM #TrialUpdate #SOHO2025 #MedSky

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The first trial of #Rituximab plus #Lenalidomide in newly diagnosed #FollicularLymphoma in China identified PU.1 as a key regulator of PD-L1/4-1BBL signaling and highlighted dual PD-L1/4-1BB targeting as a promising treatment. #medsky

#OpenAccess in #STTT: doi.org/10.1038/s413...

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AMP just published!
"Pure Red Cell Aplasia in Follicular Lymphoma with Bone Marrow Involvement and Isoniazid Exposure"

Full paper here:
www.actamedicaportuguesa.com/revista/inde...

#isoniazid #latenttuberculosis #drugtherapy #follicularlymphoma #pureredcellaplasia #rituximab #actamedicaportuguesa

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Successful salvage therapy of ruxolitinib on interstitial pneumonia after long COVID or post-COVID-19 syndrome with follicular lymphoma: two case reports and literature review Successful salvage therapy of ruxolitinib on interstitial pneumonia after long COVID or post-COVID-19 syndrome with follicular lymphoma: two case reports and literature review

Esp as the alternative salvage therapy of ruxolitinib on interstitial pneumonia after #longCOVID or #postCOVID syndrome with #follicularlymphoma in
2 #casereports with unvaccinated patients
cco.amegroups.org/article/view....

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Acalabrutinib Plus Lenalidomide and Rituximab Is Safe and Active in Untreated Follicular Lymphoma | OncLive Acalabrutinib plus lenalidomide and rituximab displayed activity and had a tolerable safety profile in first-line follicular lymphoma.

Acalabrutinib Plus Lenalidomide and Rituximab Is Safe and Active in Untreated Follicular Lymphoma #hematology #oncology #follicularlymphoma
www.onclive.com/view/acalabr...

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Tafasitamab May Maintain Quality of Life Outcomes in FL - Hematology Advisor Researchers sought to determine whether adding tafasitamab to lenalidomide plus rituximab would maintain quality of life outcomes for patients with FL.

Adding tafasitamab to lenalidomide plus rituximab combination is unlikely to reduce QoL outcomes, despite evidence that the addition may lead to clinically meaningful improvements in PFS in the R/R #follicularLymphoma setting. Presented at #SOHO2025.

https://bit.ly/4nkVg62

#lymsm

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Long-Term Data Confirm Early Rituximab Monotherapy Delays New Treatment in Advanced, Asymptomatic LTBFL | ASH Clinical News | American Society of Hematology

According to new long-term data, among patients with advanced-stage, asymptomatic low-tumor-burden #FollicularLymphoma, early #rituximab monotherapy delayed the TTNT to more than 15 years, compared with less than six years seen with watchful waiting: ow.ly/luEa50WRTVZ
#HemeSky #lymphoma #HemeOnc

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Check out this new publication by lead author Paolo Strati in Nature Communications from a Phase 2 trial in patients with advanced #follicularlymphoma using Foresight CLARITY™, achieving ultra-sensitive #MRD detection and outcome prediction. Read here: bit.ly/3I3Vdg4

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Hematology Weekly News – August 11th 2025 🔬🧬 Hematology Updates: AML Dose Escalation, Fast Track in CLL, Lymphoma Breakthroughs and More From AML dosing escalations to landmark […] The post Hematology Weekly News – August 11th 2025 appeared first on LucidQuest Ventures.

FYI: LucidQuest Views >>> Hematology Weekly News – August 11th 2025 #News #AML #CLL #follicularlymphoma #hematology Comment below!

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Hematology Weekly News – August 11th 2025 🔬🧬 Hematology Updates: AML Dose Escalation, Fast Track in CLL, Lymphoma Breakthroughs and More From AML dosing escalations to landmark […] The post Hematology Weekly News – August 11th 2025 appeared first on LucidQuest Ventures.

ICYMI: LucidQuest Views >>> Hematology Weekly News – August 11th 2025 #News #AML #CLL #follicularlymphoma #hematology Comment below!

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Hematology Weekly News – August 11th 2025 🔬🧬 Hematology Updates: AML Dose Escalation, Fast Track in CLL, Lymphoma Breakthroughs and More From AML dosing escalations to landmark […] The post Hematology Weekly News – August 11th 2025 appeared first on LucidQuest Ventures.

LucidQuest Views >>> Hematology Weekly News – August 11th 2025 #News #AML #CLL #follicularlymphoma #hematology Comment below!

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📣 New ESMO #ClinicalPracticeGuideline on #lymphomas: evidence-based recommendations for all major #lymphoma subtypes, updated as needed as an ESMO Living Guideline, reflecting developments in Tx.
#DLBCL #PCNSL #FollicularLymphoma #HodgkinLymphoma #ESMOGuidelines

🔗 buff.ly/2ZYJc2c

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Following #18ICML, we had the pleasure of catching up with Nilanjan Ghosh to hear his highlights in #NonHodgkinLymphoma from this year’s meeting.🩸

Click here for the comprehensive overview:
👉 buff.ly/RQDPS8G

#DLBCL #MantleCellLymphoma #FollicularLymphoma #LYMsm #CTSM #Lymphoma #ImmunoOnc

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