Prioritization of candidate genes reveals high-quality candidates that are known to influence neurodevelopment and synaptic plasticity and be druggable.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #drugtargetprioritization #genomewideassociationstudy #multispeciesanalysis #systemsbiology

Hundreds of genetic links to osteoarthritis unlocked - PharmaTimes Study paves the way for personalised therapies for osteoarthritis sufferer

#osteoarthritis #personalisedtherapies #genomewideassociationstudy #geneticdata #geneticvariations #osteoarthritisprevalence #biomedicaldatasets #geneticdiseaseassociatedvariants #osteoarthritisdevelopment #circadianclock #signallingpathways #diseasemechanisms
pharmatimes.com/news/hundred...

Largest ever genome-wide association study uncovers new drug targets and potential therapies for osteoarthritis – BioNews Central A combined study of genetic data from nearly 2 million people—including about 500,000 with osteoarthritis and 1.5 million controls—found 962 genetic markers linked to the condition, 513 of which were new. ...

A combined study of #GeneticData from nearly 2 million people—including about 500,000 with #osteoarthritis and 1.5 million controls—found 962 #GeneticMarkers linked to the condition, 513 of which were new.
#GenomeWideAssociationStudy #GWAS #DrugTargets #TherapeuticTargets