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Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study Abstract. In this international, multicenter prospective study, implementing penicillin direct oral challenge (DOC) using a digital toolkit was acceptable,

"Among 5121 participants assessed, 1573 (30.7%) underwent DOC, of which 1502 (95.5%) were delabeled." - that's a lot of penicillin allergy mislabelling out there! 😲

However... DOC.. more likely to be prescribed penicillin and less likely WHO “Watch” or “Reserve” antibiotics #IDSky #ClinMicro #AMR

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Positive, But Wrong | IDHub Case A neutropenic BMT recipient with a positive CrAg and skin lesions that pointed elsewhere. Featuring Trichosporon asahii. Interactive infectious diseases case from IDHub.

A false positive CrAg? #IDsky #idboardreview #idmeded #meded #infectiousDiseases infectiousdiseasehub.com/cases/tricho...

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41-yo♂️untreated #HIV infection, unprotected #sex with a♂️later diagnosed with syphilis : 9-month of annular, hyperpigmented rash, ulcerating lesions on the foot & chest

🔬: lichenoid infiltrate endothelial hyperplasia & a dense plasma cell infiltrate
1/3

doi: 10.1093/ofid/ofx139
#IDSky #dermatology

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Cover of the mini zine - my infectious disease is life, issue number 13

Cover of the mini zine - my infectious disease is life, issue number 13

On Monday, I was privileged to hear stories from the 90s and 2000s

On Tuesday, I sent some strategic emails

On Monday, I was privileged to hear stories from the 90s and 2000s On Tuesday, I sent some strategic emails

On Wednesday, well, patient asked the best questions, don’t they?

On Wednesday, well, patient asked the best questions, don’t they?

On Thursday, it was like at the Babel tower

On Friday, I remembered our resilient and tenacious bunch

On Thursday, it was like at the Babel tower On Friday, I remembered our resilient and tenacious bunch

A mini zine about My Infectious Diseases Life
Issue #13
survivors, intrigue, questions, confusion, cacti

#IDSky #MedSky #zine

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🎙️ Just published Communicable E50: Quarterly catch-up

Hosted by Emily McDonald, Thomas Tängdén and Navaneeth Narayanan

Listen on #Communicable: https://share.transistor.fm/s/10d045b8

#IDSky #clinmicro

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Red Blood Cell Exchange Transfusion for Severe Babesiosis This multicenter cohort study evaluates whether red blood cell exchange transfusion improves clinical outcomes among hospitalized adult patients with severe babesiosis.

Retrospective multicenter of severe babesia in 🇺🇸between 2010-2024

Despite higher parasitemia (14.0% vs 7.2%), the 1/3 that got exchange transfusion within 7 days had lower composite 30 day mortality and readmission (aOR, 0.22; 95% CI, 0.09-0.51)

jamanetwork.com/journals/jam...

#IDSky

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Infectious mastitis guidelines released for the USA US guidelines have been published for the diagnosis and treatment of the three most common breast infections.

#MedNews - US guidelines have been published for the diagnosis and treatment of the three most common breast infections.

Full story 👉 buff.ly/0SWDw74

#IDSky #Mastitis

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💡There are still hotel rooms available with our official congress partners at Congrex Switzerland. Book today and see you soon in Munich at #ESCMIDGlobal! https://ow.ly/XWQx50YCoSM

#IDSky #clinmicro

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Episode 25 - Don’t Mistake Silence for Ignorance: Clinical Reasoning and Timing in Infectious Diseases Podcast Episode · The Host Response: A FirstcallID Podcast · April 5 · 5m

New episode 🎧 The Host Response

Not every thought needs to be said out loud.

In ID, timing matters. What you say, when you say it, and what you hold back.

Don’t mistake silence for ignorance.

Listen on Apple or Spotify

#idsky #meded

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I share here the visual abstract of an important article from our group in colab with the groups of Dr Toni Torres (Hospital Clinic) and Rosario Menendez (Hosp La Fe) identifying Lymphopenic Community Acquired Pneumonia as a phenotype associated with mortality doi: 10.1016/j.ebiom.2017.09.023 #IDsky

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#Medsky🧪 #IDsky #pedsky #publichealth Pediatric LC #Longcovidkids includes a heterogenous collection of symptoms affecting almost every organ system, with age varying symptom differences noted between elementary school age children and adolescent

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The draft document for new ESCMID guidelines is open for comments by ESCMID members. More info can be found on the website by viewing the 'Under public consultation' tab.

Request the manuscript and submit your comments before the deadline on 20 April.

https://ow.ly/zGf550YxIWE

#IDSky #clinmicro

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The Sweet Smell of Trouble | IDHub Case Fever, weight loss, and a multiloculated liver abscess — with a blood culture plate that smells like butterscotch. Featuring Streptococcus anginosus group, Streptococcus anginosus, Streptococcus inter...

A Sweet Organism #IDsky #idboardreview #idmeded #meded #infectiousDiseases
infectiousdiseasehub.com/cases/strep-...

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#IDSky #MedSky #EpiSky

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Has anyone else seen this with omadacycline? I have once. #IDSky

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Autoantibodies Against Type I Interferons are a Prominent Feature in SARS-CoV-2 Fatal Disease and Hospitalization Autoantibodies against type I interferons, MPO and ACE2 are associated with COVID-19 severity and poor outcomes, show increasing titers overtime, and corre

Hospitalized patients with COVID in 2020 had autoantibodies to interferons, impairing their ability to fight the virus, and ACE2, which affected their ability to regulate inflammation. Probably helps to explain the huge mortality reduction that we saw with corticosteroids #IDSky

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Images in Clinical Medicine 
Minocycline-Induced Hyperpigmentation 

Panels A and B: Photos of the patient's forearms and shins taken during the physical examination. 
Panels C and D: Photos taken at the 6-month follow-up.

Images in Clinical Medicine Minocycline-Induced Hyperpigmentation Panels A and B: Photos of the patient's forearms and shins taken during the physical examination. Panels C and D: Photos taken at the 6-month follow-up.

A 68-year-old woman with rosacea presented with a 6-week history of dark patches on the skin of her arms and legs. Two weeks before the onset of the skin changes, she had started taking minocycline daily. Read the full case details: nej.md/47zLnw9

#MedSky #DermSky #IDSky

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Penetrating the Prostate. Check out this week’s KASIC pearl to learn about Antimicrobials for Acute Bacterial Prostatitis kymdro.org/kasic/?p=8900

#IDsky #AntimicrobialResistance #antimicrobialstewardship #rxsky #pharmacy #FOAMed #NPs #PAs

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Top Infectious Disease News Stories Week of March 29 - April 4 | Contagion Live This week, read about omadacycline as an oral treatment option for Mycobacterium abscessus pulmonary disease, combining immunotherapy with antifungals for fungal infections, this year's Peggy Lillis F...

This week, read about omadacycline as an oral treatment option for Mycobacterium abscessus pulmonary disease, combining immunotherapy with antifungals for fungal infections, this year's Peggy Lillis Foundation's C diff meeting, and more. #IDsky #Medsky

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State-of-the-Art Review: Managing Vulvovaginal Candidiasis Vulvovaginal candidiasis (VVC), especially in its recurrent form, significantly impacts women's health. This review explores its pathophysiology, risk fact

Managing vulvovaginal candidiasis…

academic.oup.com/cid/article/... #IDSky

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#Medsky🧪 #IDsky #immunosky #publichealth #Vaccinesmatter BNT162b2 vaccination provided substantial protection & robust antibody responses among LTC residents, including those of very advanced age, supporting the effectiveness of mRNA vaccination in highly vulnerable institutionalised populations

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Acute Hepatitis B among PWH Switched to Long-Acting Cabotegravir/Rilpivirine: The Context Matters Rémi Rouget, Nadia Valin, Antoine Bachelard, Christia Palacios, Amélie Chabrol, Antoine Faycal, Marc-Antoine Valantin, Valérie Pourcher, Jade Ghosn, Gilles

Important data on HBV with LA-CAB/RPV from France 🇫🇷

-1247 received LA-CAB/RPV from 5 health depts
-290 (7.5%) had ➖ HBVsAB of which 75 (6.0%) had ➕ anti-HBc Abs.

8 developed acute HBV on therapy:
3️⃣ new infection
5️⃣ relapse (3 of which isolated HBVcAB pos)

academic.oup.com/cid/advance-...

#IDSky

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Michigan measles outbreak has 8 cases. Cost to keep it contained approaches $100,000. “You’ve got these bigger outbreaks, they’re kind of sending out sparks,” said Dr. William Moss, a professor at the Johns Hopkins Bloomberg School of Public Health.

Michigan measles outbreak has just 8 cases. The cost to keep it from spreading is approaching $100,000. It is one of 17 new measles outbreaks across the U.S. — large and small — since January. My latest ‬… 👇 www.healthbeat.org/2026/04/03/m...
#publichealth #IDsky #medsky #EpiSky

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#Medsky🧪 #IDsky #immunosky #publichealth The E protein is known to localize to the ER & ERGIC membranes with M . Both E & M are required for viral budding, working together to induce membrane curvature and the budding off of them ERGIC membrane

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Read the commentary on the society's initiatives to reduce its carbon emissions, including at #ESCMIDGlobal2026. https://ow.ly/eHS950YBKzX

Attending #ESCMIDGlobal2026 & travelling sustainably? Share your journey w/ a selfie & join our campaign using #ESCMIDGreenTravel 🍀

CMI Communications #IDSky

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Occurrence of autochthonous neurocysticercosis in Germany: a case report This rare case of autochthonous neurocysticercosis in rural Germany underscores the need to consider NCC in patients with new‑onset generalized seizures and compatible neuroimaging findings, even in…

#MedCase - This rare case of autochthonous #neurocysticercosis in rural Germany underscores the need to consider NCC in patients with new‑onset generalized seizures and compatible neuroimaging findings, even in non‑endemic settings.

👉 buff.ly/ufiCXGE

#NeuroSky #IDSky

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A 37-YO ♀️, #sinusitis: headache, fluctuating forehead swelling.

MRI: opacification of all paranasal sinuses, osteomyelitis of the frontal bone with erosion of anterior frontal sinus wall & a subperiosteal abscess in the patient’s forehead.
½

doi.org/10.1503/cmaj...
#MedEd #IDsky

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We are happy to announce our social media ambassadors at #ESCMIDGlobal2026! These 4 experts will lend their pen & platform to help us cover the congress in Munich. Learn more about our ambassadors: https://ow.ly/FRMT50YBbGX

Everyone can join the conversation w/ #ESCMIDGlobal2026! #IDSky #clinmicro

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The Loyal Companion | IDHub Case Septic shock and meningitis in an asplenic patient whose dog never bit her. Featuring Capnocytophaga canimorsus. Interactive infectious diseases case from IDHub.

What's the most likely diagnosis? #IDsky #idboardreview #idmeded #meded #infectiousDiseases
infectiousdiseasehub.com/cases/capnoc...

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Closed Defense (with my fantastic committee) ✅️
Dissertation and Edits ✅️
Open Defense (thanks to everyone who attended!) ✅️

I have too many people to thank for their support of my professional development, and am excited to go back to med school as #DrKyle. #FGLI #mstp #MedSky #PhDSky #IDSky

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