Recent review highlights the role of the #Immunoproteasome in #Diabetes and its associated complications, positioning it a potential target for innovative therapies. #DiabetesResearch #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

James J. Driscoll, MD, PhD | Immunoproteasome Activation Enhances the Recognition of Tumour Cells and Boosts Anticancer Immune Responses • scientia.global The correct functioning of the human immune system depends on its ability to recognise danger, such as tumour cells, viruses, and bacteria. Scientists are learning how immunoproteasome activation can ...

Boosting immunoproteasome activity helps tumour cells expose hidden antigens, sharpening T‑cell recognition and enhancing anticancer immune responses. Learn more: www.scientia.global/james-j-dris... #CancerImmunotherapy #Immunoproteasome

Online now - the Review "Proteasome-derived peptides: separating the trash from the recycling" from Anna Brennan, Taylor Church, and Seth Margolis.

#peptides #antimicrobialpeptides #proteasomederivedpeptides #immunoproteasome #neuronalmembraneproteasome

authors.elsevier.com/a/1lQDv3S6Gf...

🚀 Milestone Moment for iProtics! | iProtics 🚀 Milestone Moment for iProtics! We’re thrilled to share that iProtics has secured €450,000 in innovation funding through the NWO Take-Off Phase 2 program — a key step forward in bringing our immunopr...

Great to see that #iProtics receives a Phase 2 award by the Take-off program of NWO to further develop their company with a focus on targeting the #immunoproteasome.

It is amazing to see the development of this research that started in the LED3 hub.
www.linkedin.com/posts/iproti...

Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance Refractory PsA patients exhibit dysregulated immunoproteasome and MHC-I machinery, highlighting potential therapeutic targets.

Recently in #Science #Immunology: researchers @ Weizmann & Tel Aviv Sourasky characterize synovial fluid immune compartment of #PsoriaticArthritis patients. #Immunoproteasome- & #MHCI -related genes ↑ in patients w refractory disease. Targeting immunoproteasome may be possible therapeutic approach!

Any #proteasome or #immunoproteasome people here already? A side project developed towards proteasomal degradation and I could use some review/paper recommendations as well as names of labs that are leading the field 🙏🤗