Scientists turn plastic waste into Parkinson’s drug levodopa using engineered bacteria Researchers engineered a two-strain microbial system that converts PET-derived terephthalic acid into levodopa, overcoming key bottlenecks in transport and enzyme inhibition. The proof-of-concept proc...

♻️ Scientists have turned plastic waste into levodopa, a key Parkinson’s drug, using engineered bacteria. Medicine from trash? www.news-medical.net/news/2026031... #Levodopa #Parkinsons

Flower of Vicia faba, commonly known as the broad bean

Like so many drugs Levodopa was also found by looking at nature and analyizng the components of plants. Like Vicia faba, commonly known as the broad bean.

https://en.wikipedia.org/wiki/Vicia_faba

Bial launches new sublingual Parkinson’s treatment in UK - PharmaTimes Sublingual apomorphine film offers rapid relief for OFF episodes

#Bial #Kynmobi #parkinsonsdisease #parkinsonstreatment #neurology #sublingualParkinsonstreatment #UK #Sublingualapomorphine #OFFepisodes #apomorphine #OFFperiods #levodopa #dopaminergictherapies #PDpatients #ClinicalNeuroscience #innovativetherapies #Parkinsonspatients
zurl.co/vacN4

#Levodopa #Gender #Dyskinesia #Dystonia #Hallucinations #Confusion #Dopamine #Dysregulation #Symptoms

Bioengineered gut bacterium synthesizing #levodopa alleviates motor deficits in models of #Parkinsons disease

www.sciencedirect.com/science/arti... #OpenAccess #MicroSky #MedSky

ESTREL - Keine Verbesserung der motorischen Erholung nach Schlaganfall durch Levodopa | Departement Klinische Forschung | Universität Basel TAXIS Substudie: Genomische Tests sind aus Primärtumorgewebe verlässlicher als aus Lymphknoten.

🧠 Ergebnis der ESTREL-Studie: #Levodopa bringt in der Schlaganfall-Reha keinen Zusatznutzen für die motorische Erholung.

👉 dkf.unibas.ch/de/aktuell/e...

#DKFBasel #ClinicalResearch #Stroke #Rehabilitation #ESTREL

optimising dopaminergic medications like #levodopa can reduce the frequency & severity of episodes. And some forms of FOG are not responsive to medication.
- Physical therapy & rehabilitation: Physical therapists can provide targeted training that improves balance, walking, physical performance.

All'ospedale Molinette di Torino una terapia innovativa contro la malattia di Parkinson in fase complicata: l'infusione continua di levodopa È stata testata su una trentina di pazienti dallo scorso ottobre dando ottimi risultati

Salute

All'ospedale Molinette di #Torino una terapia innovativa contro la malattia di #Parkinson in fase complicata: l'infusione continua di #levodopa.

È stata testata su una trentina di pazienti dallo scorso ottobre dando ottimi risultati.

Key point: CSF tests in both patients revealed decreased levels of monoamine metabolites.
doi.org/10.1002/epi4...

#epilepsy #epilepsiaopen #ilae #levodopa #monoaminemetabolites #dopaminetransporter #singlephotonemissioncomputedtomography

Brain study challenges long-held views about Parkinson's movement disorders Researchers uncovered new findings about involuntary muscle movements that come with long-term administration of Parkinson's drug levodopa.

Researchers uncovered new findings about involuntary muscle movements that come with long-term administration of Parkinson's drug levodopa. #neuroscience
#Parkinson #levodopa #dyskinesia #motorcortex #ketamine

Strongly recommended #Parkinsons Starter Pack. #dopamine #levodopa #PLM #MovementDisorders #GaitStudies

Our network meta-analysis:
#DBS of the #subthalamus worsens falling in #parkinson's

No positive/negative effect of pallidal stimulation or intestinal #levodopa

Newest subcutaneous levodopa or foslevodopa pumps improve falling, a first in advanced treatments!

jnnp.bmj.com/content/earl...

#Parkinson meeting in Warsaw with @alfonsofasano.bsky.social discussing #levodopa infusion strategies and surgical treatments

Debate: would you offer subcutaneous #levodopa BEFORE other more invasive options?
The majority at #CMDS2023 says yes!
Drs Bouchard and Sarna emphasized the easy access but also the high rate of discontinuation.

Managing Levodopa and Eating Protein: Not a One-Size Fits... In a recent study, researchers review the current approac...

Read the full story at ufh-fixel-a2.sites.medinfo.ufl.edu/2023/08/02/managing-levo...

#Nutrition #PD #Levodopa #Protein #UFlorida #UFHealth #FixelInstitute

🧵(5/5)

Just published in @MDJ_Journal the very much needed updated #levodopa dose equivalency in #Parkinsons

In great company of @angelo_antonini, @AlbertoEspay, @ctrenkwalder1, @KRayChaudhuri1, @petryschmelzer and many more! ...

Is there a long duration response, motor learning and plasticity with #levodopa treatment? 15 patient study in drug naive #parkinsonsdisease High dose 250mg over 15 days; physiology showed unique findings. Not sure I buy all conclusions apply to...

The role of PD #nurse in #Parkinson’s care is as invaluable as not properly recognized.

This is our international #levodopa intestinal gel course: Yu-Yan Poon and Nick Feugas are running the show! Everyday I learn so much from them.

Does replacing dopamine help with facial masking in PD? »... Researchers at the University of Florida study the impact...

Read the full story - fixel.ufhealth.org/2022/11/14/does-replacin...

#DopamineReplacement #Levodopa #PD #Parkinson #MuscleStiffness #FacialExpressions
@UFPHHP @FixelInstitute @uflorida @UFMBI @UFHealth

🧵 (5/5)

Odd that we have guidelines till #Parkinson is treated with device-aided therapies, after which we have no data.

A year ago we published our #levodopa vs #dopamine agonist RCT after #DBS.

Out now, COSMOS explored this issue after levodopa intestinal infusion.

When discussing the 'Myths' in the use of #levodopa in #Parkinson, we should also pay attention to factors such as disease duration and surgical options based on patient's age. In our new paper I took the liberty of modifying @AlbertoEspay's figure. Comments are welcome! 1/2