Lipotoxicity-induced miR-34a mediates communication driving liver fibrosis.
#LiverFibrosis #MicroRNA #Inflammation #HepaticStellateCells #Lipotoxicity
www.sciencedirect.com/science/arti...

Elevated miR-34a induced by lipotoxicity and inflammation mediates pathophysiological communication between hepatocytes and hepatic stellate cells in liver fibrosis

A research team from @qubelfastofficial.bsky.social found that elevated #miR34a, induced by #lipotoxicity and metabolic inflammation, is a key driver of progressive liver injury, from simple steatosis to #MASH and ultimately to #LiverFibrosis. #medsky

#OpenAccess:https://buff.ly/K6aAndU

Vascular endothelial growth factor B-mediated fatty acid flux in the adipose-kidney axis contributes to #lipotoxicity in #diabetickidneydisease

doi.org/10.1016/j.kint.2024.11.026

#OpenAccess #lipolysis #NephSky #MedSky