Jacob Hobbs presenting at #SFEBES2026 #conference 🔬 Sharing findings on Tubby as a novel regulator of early #BrownAdipocyte differentiation and its role in #PPAR signalling and #lipolysis
Come and say hello, Poster 133
@mark-christian-lab.bsky.social
@amandacoutts.bsky.social
#NTU
#SHIMR_NTU

New year resolution to post more! Proud of @yushengyeh & @RazaniLab members for their ATVB review this month comparing/contrasting newly discovered #adipocyte #lipolysis via #lysosome #LIPA vs. known cytoplasm #ATGL in #cardiometabolic #CVD 💪
www.ahajournals.org/doi/10.1161/...

Promising Phase 2 Results for AYP-101 by AMI Pharm: A Non-Surgical Breakthrough in Lipolysis AMI Pharm's AYP-101 shows promising results in Phase 2 trials for non-surgical lipolysis, paving the way for an innovative treatment method for submental fat reduction.

Promising Phase 2 Results for AYP-101 by AMI Pharm: A Non-Surgical Breakthrough in Lipolysis #South_Korea #Seoul #AMI_Pharm #AYP-101 #lipolysis

Your brain works overtime at night to burn fat and prevent sugar crashes Researchers uncovered that hypothalamic neurons safeguard blood sugar overnight by directing fat breakdown, preventing hypoglycemia during early sleep. This subtle control system may explain abnormal…

"In the first 4 hours after u go to bed, these neurons ensure that you have enough #glucose so that you don't become hypoglycemic overnight..To do so, the neurons direct the body to burn #fat through a process called #lipolysis.": buff.ly/WR690Jv

via ScienceDaily
#sleep #hypoglycemia

Thermogenesis required fuel to burn. Supplementing NMR with additional fuel allows them to maintain a higher body temperature. Shown are line plots of NMR in the cold with and without supplemental olive oil.

🧵8/ We tested if "fuel" was limiting by supplementing lipids. This helped NMRs keep body temp higher during cold—suggesting substrate availability is important, but not the whole story. #lipolysis

Researchers uncover why women handle body fat more efficiently Women’s fat cells break down fat faster than men’s once activated, even though they require higher hormone levels to initiate the process. This may help explain why women are less prone to metabolic c...

Researchers uncover why women handle body fat more efficiently 🧬🏃‍♂️🔥 www.news-medical.net/news/2025051... #fat #metabolism #type2diabetes #obesity #hormoneresponse #exercise #physiolog #metabolichealth #lipolysis

Announcing the @BMA_Society Paper of the Month for April 2025 ! Published in @OACJournal, this study identifies a previously unrecognized role of #BMAT #lipolysis in the sub-chondral neo-osteogenesis associated with hand #osteoarthritis.

Lysosomal Acid #Lipase (Lipa/LAL) is upregulated in #AdiposeTissue during #fasting, cold exposure, and even #obesity. When we ablate #adipocyte Lipa/LAL, mice cannot undergo full #lipolysis with difficulty maintaining body temperature in cold. On #highfat diet, they become obese.

Wondered how #adipocyte #fat release #lipid via #lipolysis in #fasting, cold exposure? Multi-year Razani lab effort in @jclinical-invest.bsky.social by postdoc maven Yu-Sheng Yeh identifies #lysosome lipolysis (LAL) as major way on par with known cytosolic route (ATGL)
jci.org/articles/view/185340

👋 New article online 👉 doi.org/10.3168/jds....

✅ Our objective was to study the impact of both milking intervals and time of day on milk spontaneous lipolysis in twice-daily milking systems in 🐄

#dairy #milk #quality #lipolysis #freefattyacids #milkingrhyrhms #nycthemeralcycle #livestock

Vascular endothelial growth factor B-mediated fatty acid flux in the adipose-kidney axis contributes to #lipotoxicity in #diabetickidneydisease

doi.org/10.1016/j.kint.2024.11.026

#OpenAccess #lipolysis #NephSky #MedSky

Nile Red staining of neutral lipids and DAPI staining of DNA show apparently normal development in Anopheles gambiae mosquito embryos from AgTL2-knockdown and control females at 4–7, 21–24, 35–38 h after oviposition.

Lipid mobilization helps growth of #malaria parasites inside 🦟🦟🦟, but does it affect #mosquito reproduction? Catteruccia lab show that maternal #lipolysis is essential for embryonic development, and could be a potential target for inducing mosquito sterility #PLOSBiology 🧪 plos.io/3Dih3JU

Nile Red staining of neutral lipids and DAPI staining of DNA show apparently normal development in Anopheles gambiae mosquito embryos from AgTL2-knockdown and control females at 4–7, 21–24, 35–38 h after oviposition.

Lipid mobilization helps growth of #malaria parasites inside 🦟🦟🦟, but does it affect #mosquito reproduction? Catteruccia lab show that maternal #lipolysis is essential for embryonic development, and could be a potential target for inducing mosquito sterility #PLOSBiology 🧪 plos.io/3Dih3JU

Nile Red staining of neutral lipids and DAPI staining of DNA show apparently normal development in Anopheles gambiae mosquito embryos from AgTL2-knockdown and control females at 4–7, 21–24, 35–38 h after oviposition.

Lipid mobilization helps growth of #malaria parasites inside 🦟🦟🦟, but does it affect #mosquito reproduction? Catteruccia lab show that maternal #lipolysis is essential for embryonic development, and could be a potential target for inducing mosquito sterility #PLOSBiology 🧪 plos.io/3Dih3JU