We are extremely grateful to the #maleCNS team, incl. @janelia-flyem.bsky.social, @jefferis.bsky.social and lab, and many, many others. Backstory >> bsky.app/profile/jeff... Website >> male-cns.janelia.org
Landing and takeoff sensorimotor pathways illustrated alongside fly drawings showing behavioral responses.
How do animals channel sensory information into motor pathways to generate flexible behavioral output? Excited to share a new preprint addressing this question by leveraging the new #maleCNS connectome, behavioral experiments, and in-vivo recordings: doi.org/10.64898/202.... A long🧵...
the broader Drosophila and neuroscience fields for all of the amazing previous work that allowed this to be possible!
To search across the wonderful new #malecns on your own, check out male-cns.janelia.org
Major thanks goes to our co-authors, Claire Managan, Marisa Dreher, Elizabeth Kim, Scott Miller, Katie Boone, Alice Robie, Adam Taylor, and @kristinmbranson.bsky.social, the #malecns team, as well as our amazing colleagues @hhmijanelia.bsky.social (in other labs and teams) for their support and… 10/
Images showing cross-sections of dorsal DM4 hemilineage in the male and female EM, morphologies of all male P1 or pC1x neurons together, or morphologies of individual P1/pC1x neurons in the malecns dataset
#malecns (collaborative effort with @janelia-flyem.bsky.social @camzoology.bsky.social @mrclmb.bsky.social @jefferis.bsky.social @stuartberg.bsky.social @beckett14.bsky.social @mmcosta.bsky.social Philipp Schlegel and others) split P1/pC1x into 48 cell types based on morphology and connectivity. 3/
Excited to share our new #biorxivpreprint:
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...
We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10
And here's the official announcement from our Janelia collaborators with a fantastic visualisation from @philiphubbard.bsky.social. See more at male-cns.janelia.org/media. Downloads are humming and we have solved the first data access queries. Happy exploring! #drosophila #connectomics #malecns.