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💡Application Note: Differentiation of induced pluripotent stem cells (iPSCs) into mesoderm; zurl.co/SCl5N

The growth factors needed can be purchased as a kit saving 36%; zurl.co/ue2IN

#iPSC #mesoderm #stemcells

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1817: Germ layers - The book of science In 1817, Heinz Christian Pander discovered that animal embryos develop three layers: ectoderm, mesoderm, and endoderm.

In 1817, Heinz Christian Pander discovered that animal embryos develop three layers: ectoderm, mesoderm, and endoderm. #Poetry #Science #History #Embryology #Pander #Ectoderm #Mesoderm #Endoderm sharpgiving.com/Sharp/theboo...

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mTORC2-mediated cell-cell interactions promote BMP4-induced #WNT activation and #mesoderm differentiation in hESCs. Critical link between intracellular adhesion and the activation of canonical WNT genes. https://ow.ly/2mkF50Xe7GG

ISSCR | The Gairdner Foundation | SickKids Foundation | Cell Press

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6/9 Single-cell transcriptomic and chromatin profiling of zebrafish tumors revealed that EWSR1::FLI1 expression in neural crest cells drives a mesenchymal/mesodermal shift, with mesodermal genes like #Brachyury (T) strongly upregulated. #NCCs #mesoderm #reprogramming

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💡Application Note: Differentiation of induced pluripotent stem cells (iPSCs) into mesoderm > zurl.co/xkpyG

The growth factors needed can be purchased as a kit saving 38% > zurl.co/2Y3yV

#iPSC #mesoderm #stemcells

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✨ In this week's DB unit seminar, Michael Zhao, a postdoc in the Aulhela group, shared insights on how he uses a combination of experimental data and theoretical models to study patterning and collective behaviour in the presomitic mesoderm #Patterning #CollectiveBehavior #Mesoderm

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💡Application Note: Differentiation of induced pluripotent stem cells (iPSCs) into mesoderm

Read the full application note > zurl.co/jmcUU

Save 38% by buying the differentiation kit > zurl.co/ldNPw

#iPSC #mesoderm #stemcells

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Let me add our paper to this review of mechanical drivers of NT folding.

We showed that mammalian spinal #neuraltube folding is primarily driven by #mesoderm expansion and #zippering. #Hingepoints emerge as a result of these extrinsic forces.

www.pnas.org/doi/10.1073/...

x.com/DagmarIber/s...

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Jordi Casanova and co-workers @bist.eu @csic.es @irbbarcelona.org @ub.edu show that autocrine #Wingless constricts the #Drosophila embryonic #gut by Ca+2-mediated repolarisation of #mesoderm cells.

www.embopress.org/doi/full/10....

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Frontiers | Brachyury co-operates with polycomb protein RYBP to regulate gastrulation and axial elongation in vitro

A new paper from the Pirity lab has been published in Frontiers in Cell&DevBiol. Using 3D embryoid bodies, they have shown that #RYBP, a member of the PRC1-like #chromatin remodeling and modification complex, plays an unprecedented role in #mesoderm formation.
www.frontiersin.org/journals/cel...

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But then the Q was, are #mitochondria enriched in all neurons or in a select set of neurons. We showed that the #ENS has #neurons from 2 lineages - #NeuralCrest and #mesoderm By studying the distribution of the targeted M2 antigen, we found that the enrichment is only in mesodermal neurons (5/n)

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