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GRADE approach to rate the certainty from a network meta-analysis: avoiding spurious judgments of imprecision in sparse networks - PubMed When direct and indirect estimates of treatment effects are coherent, network meta-analysis (NMA) estimates should have increased precision (narrower confidence or credible intervals compared with relying on direct estimates alone), a benefit of NMA. We have, however, observed cases of sparse networ …

In network #MetaAnalysis (NMA) sparse networks sometimes yield bizarrely wide #ConfidenceIntervals. The solution we discovered after trying many alternatives perhaps surprising: switch from random effects to fixed effect.

pubmed.ncbi.nlm.nih.gov/30253217/

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This #metaanalysis with #TSA showed #ciprofol for #sedation had a lower incidence of injection pain and higher average #MAPs than #propofol

www.bjanaesthesia.org/article/S0007-0912(25)00...

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Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis - BMC Neu... BMC Neurology - Therapeutic plasma exchange (TPE) and intravenous immunoglobulin (IVIG) are high-cost treatments used for relapsed or refractory autoimmune neurological disorders. To compare the...

Here is the link to:
Clinical and economic outcomes of therapeutic #plasmaexchange and intravenous #immunoglobulin for treating adults with autoimmune neurological disorders: a #systematicreview and #metaanalysis
link.springer.com/article/10.1...

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Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta analysis, by Kimber et al.

Image showing visual abstract for: Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta analysis, by Kimber et al.

New systematic review by the SRI:
Clinical and economic outcomes of therapeutic #plasmaexchange and intravenous #immunoglobulin for treating adults with autoimmune neurological disorders: a #systematicreview and #metaanalysis by Kimber et al. (2026).

Link in the comments.

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Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis - BMC Neu... BMC Neurology - Therapeutic plasma exchange (TPE) and intravenous immunoglobulin (IVIG) are high-cost treatments used for relapsed or refractory autoimmune neurological disorders. To compare the...

Here is the link to:
Clinical and economic outcomes of therapeutic #plasmaexchange and intravenous #immunoglobulin for treating adults with autoimmune neurological disorders: a #systematicreview and #metaanalysis
link.springer.com/article/10.1...

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Poster for the seminar: MetaInsight v7: Making a comprehensive app for network meta analysis reproducible

Poster for the seminar: MetaInsight v7: Making a comprehensive app for network meta analysis reproducible

I’m giving a seminar on 20th April about refactoring crsu.shinyapps.io/MetaInsight/ to use {shinyscholar}, producing crsu.shinyapps.io/MetaInsight_... Details and sign up: www.eventbrite.co.uk/e/crsu-webin... A shorter version is also coming to R/Medicine in May
#rstats #metaanalysis #openscience

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E-E-A-T Meta-Analysis: SEO specialist & copywriter Daniel Beránek A comprehensive web presentation of the E-E-A-T meta-analysis evaluating Daniel Beránek's Experience, Expertise, Authoritativeness, and Trustworthiness as an SEO specialist and copywriter. Features in...

#EEAT #MetaAnalysis of #SEOspecialistAndCopywriterDanielBeranek by #ManusAI

eeat-analysis-b4jrwdnu.manus.space

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E-E-A-T Metaanalýza · Daniel Beránek Komplexní průřez hodnoceními AI modelů. Subjekt: SEO specialista a copywriter Daniel Beránek. Syntéza výstupů Claude, Copilot, Mistral, Manus, Kimi, Gemini, ChatGPT, Grok, Seznam Asistent.

#metaanalysis #eeat #claude vibecode: #macaly

macaly-hqpnq1cnpjs45ur7xate74ba.macaly.app

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Metaanalýza E-E-A-T SEO specialist a copywriter Dan Beránek Komplexní metaanalýza E-E-A-T hodnocení SEO specialisty a copywritera Daniela Beránka na základě 10 nezávislých AI analýz.

#metaanalysis #eeat #claude vibecode: #lovable

meta-analyza-e-e-a-t-daniel-beranek.lovable.app

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GRADE approach to rate the certainty from a network meta-analysis: addressing incoherence - PubMed This article presents official guidance from the Grading of Recommendations Assessments, Development, and Evaluation (GRADE) working group on how to address incoherence when assessing the certainty in the evidence from network meta-analysis. Incoherence represents important differences between direc …

Assessing #incoherence – differences between direct and indirect estimates in a network #MetaAnalysis (NMA) can be challenging. This lucid article describes the #GRADE approach to addressing the issue

pubmed.ncbi.nlm.nih.gov/30529648/

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Still time to join our #MetaAnalysis in R course with @asanchez-tojar.bsky.social & @shreyadimri.bsky.social (11–14 May, online)!

Learn systematic reviews, effect sizes, meta-analysis & meta-regression in R with hands-on exercises & real datasets.

www.physalia-courses.org/courses-work...

#RStats

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#SystematicReview #MetaAnalysis #OpenScience #MetaScience #EducationResearch

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New meta-analysis shows stomatal density and index respond more to light intensity than atmospheric CO₂, highlighting caveats for paleo-CO₂ reconstructions based on fossil leaf traits.
www.sciltp.com/journals/Pla...
#CO2 #lightintensity #metaanalysis #paleoclimatology #stomataldensity #stomatalindex

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#SeedOilResearch #OxidizedLDL #HealthDebate #NutritionScience #MetaAnalysis #ScientificStudies #RoseCornOil #HealthyFats #FoodScience #wellbeingcoach #wellnessblog #wellnesswins #wellnessmatters #Wellness

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Lower risk of cognitive impairment & dementia linked to adherence to plant-based diets, particularly those rich in healthful plant foods, a new meta-analysis suggests: doi.org/10.1016/j.tj... #Dementia #Health #Nutrition #PlantBased #Diets #MetaAnalysis

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I spent about 20 hours in the last week writing, from scratch, matlab code to run simple #metaanalysis. I had to search for the original #stats papers, browse Cochran manuals & try to understand R/CRAN stuff.

The code already exists in R (JASP, Jamovi, etc) & likely in Matlab, so why not use 'AI'?

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Image showing a PICO summary for:

Risk prediction models for blood transfusion in patients undergoing total hip and knee arthroplasty: a #systematicreview and meta-analysis.
by Liu et al.
featured in the Transfusion Evidence Alert - February 2026

Image showing a PICO summary for: Risk prediction models for blood transfusion in patients undergoing total hip and knee arthroplasty: a #systematicreview and meta-analysis. by Liu et al. featured in the Transfusion Evidence Alert - February 2026

New from the #Transfusion Evidence Alert:

Risk prediction models for blood transfusion in patients undergoing total hip and knee arthroplasty: a #systematicreview and #metaanalysis.
by Liu et al.
#MedSky

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GRADE approach to rate the certainty from a network meta-analysis: addressing incoherence - PubMed This article presents official guidance from the Grading of Recommendations Assessments, Development, and Evaluation (GRADE) working group on how to address incoherence when assessing the certainty in the evidence from network meta-analysis. Incoherence represents important differences between direc …

#Incoherence in a network #MetaAnalysis occurs when direct and indirect estimates of the effect of an intervention differ substantially: what to do, and how to use #GRADE to rate the #CertaintyofEvidence? This paper answers the questions.

pubmed.ncbi.nlm.nih.gov/30529648/

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Efficacy and safety of ruxolitinib for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation: a systematic review and meta-analysis INTRODUCTION: Graft-versus-host disease (GVHD) remains a major complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Despite standard prophylaxis, acute and chronic GVHD i...

#StemCellEvidence link to:

Efficacy and safety of ruxolitinib for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation: a #systematicreview and #metaanalysis
by Xie e al.
www.stemcellevidence.com/alerts/artic...
#MedSky

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Image showing a PICO summary for:

Efficacy and safety of ruxolitinib for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation: a #systematicreview and #metaanalysis 
by Xie e al.
featured in the Stem Cell Evidence Alert - February 2026

Image showing a PICO summary for: Efficacy and safety of ruxolitinib for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation: a #systematicreview and #metaanalysis by Xie e al. featured in the Stem Cell Evidence Alert - February 2026

From the #StemCellEvidence Alert:

Efficacy and safety of ruxolitinib for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation: a #systematicreview and #metaanalysis
by Xie e al.
#MedSky

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NEW in @Geoderma_Jrnl
Organic amendments reshaped chemical composition of #soil organic matter: A meta-analysis

doi.org/10.1016/j.ge...

#SoilOrganicMatter #SoilOrganicCarbon #sequestration #carbonsequestration #soil #agriculture #global #Fertilisers #carbon #review #MetaAnalysis

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www.iqscorner.com/2026/03/research-alert-relationship-between.html #Gq #EF #executivefunctions #Gwm #workingmemory #math #metaanalysis #schoolpsychology #schoolpsychologists #SLD #SPED

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Spending some time coding the "trim and fill" algorithm for #metaanalysis in matlab, working from some existing R code (which i don't understand) and the original paper (which i also don't understand). Plan to test it against results in JASP (which i don't understand). What could go wrong? #stats

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NEW in @Pedosphere1991
Biochar increases crop yield in salt-affected soils: A #metaanalysis
doi.org/10.1016/j.pe...

#SoilOrganicMatter #soil #agriculture #salinity #alkaliniy #sodicy #biochar #global #landuse #Fertilisers #Phosphorus #Rice #wheat #maize

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Aerobic exercise may be most effective for relieving depression and anxiety symptoms – BioNews Central A systematic review and meta-analysis of available evidence finds that aerobic exercises, such as running, swimming, and dancing, may be the most effective for relieving symptoms of depression and anx...

A #SystematicReview and #MetaAnalysis of available evidence finds that #AerobicExercises, such as running, swimming, and dancing, may be the most effective for relieving symptoms of #depression and #anxiety.
#MentalHealth #PhysicalActivity #Exercise

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A Risk of Bias assessment from a published meta-analysis. Table shows 30 studies rated on 10 criteria as 'Yes', 'Uncertain', or 'No'. The overall bias rating is taken as the worst rating across all criteria per study, so a single 'No' rating gives the study a 'High' bias. This particular meta-analysis rated all 30 studies as 'High bias'. So this exercise does not help differentiate between studies.

A Risk of Bias assessment from a published meta-analysis. Table shows 30 studies rated on 10 criteria as 'Yes', 'Uncertain', or 'No'. The overall bias rating is taken as the worst rating across all criteria per study, so a single 'No' rating gives the study a 'High' bias. This particular meta-analysis rated all 30 studies as 'High bias'. So this exercise does not help differentiate between studies.

In #SystematicReview & #MetaAnalysis authors often do #RiskOfBias (RoB) assessments, quantifying whether included studies are 'biased'

Studies may be rated on multiple criteria as Low/Moderate/High bias. The overall RoB may then be the *maximum* level per study

This can produce tables like this:

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Limus- versus paclitaxel-coated balloons for coronary in-stent restenosis: meta-analysis of randomized controlled trials - Cardiovascular Intervention and Therapeutics Drug-coated balloons (DCB) are increasingly utilized for treating in-stent restenosis (ISR), yet the comparative efficacy of limus-coated balloons (LCBs) versus paclitaxel-coated balloons (PCBs) remai...

LCBs are non-inferior to PCBs for treating coronary ISR, with similar clinical outcomes. Supports LCBs as a viable alternative. #Biolimus #MetaAnalysis #Paclitaxel #Sirolimus
link.springer.com/article/10.1...

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Sometimes it's the little things. Renamed "uncategoried" to "unreviewed" during extraction. This change was made because of user feedback, so if you notice something that you think could be more clear/easier, let us know!
#neuroscience #openscience #metaanalysis

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NEW in Frontiers in Soil Science
Biochar raises #soil health and reduces greenhouse gas emissions in #arid lands
doi.org/10.3389/fsoi...

lead by Said Al-Ismaily & Daniel Blackburn

#SoilOrganicMatter #sequestration #carbonsequestration #soilhealth
#CO2 #N2O #CH4 #global #landuse #metaanalysis

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New #preprint from the lab led by talented pharmacy grad student Ella Schwab: "Mouse macrophages from diverse niches show generally divergent age-related transcriptional remodeling signatures" showing a #metaanalysis of 🐭 macrophage aging RNA-seq data.🧪🖥️🧬 🔬. A🧵 1/4
www.biorxiv.org/content/10.6...

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