A blueprint for broadly effective bacteriophage-antibiotic cocktails against bacterial infections Nature Communications - The application of phage therapy for multidrug-resistant infections is mainly limited to personalized therapy due to the narrow host range of individual phages. Here, Kim et...

The narrow host range of phages limits #PhageTherapy applications

Kim et al. present a blueprint for the development of broad-spectrum phage-antibiotic combinations

@pbollyky.bsky.social ‪@ebburgenermd.bsky.social‬

#microNatComms #microbiology

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Scheme showing a proposed mechanism for the release of SCC cassettes and DNA molecules encoding anti-phage systems, following phage infection

SCC mobile genomic islands are known to spread #AntibioticResistance among staphylococci

This work shows that phage infection stimulates SCC mobilization & this facilitates the spread of #antiphage defenses

#microNatComms #microbiology #bacteria

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#microNatComms #microbiology #archaea

Two great #microNatComms #microbiology papers!

A tuneable minimal cell membrane reveals that two lipid species suffice for life Nature Communications - All cells are encapsulated by a membrane of complex lipidic composition, and understanding the roles of different lipids in membrane function is experimentally challenging...

All cells are encapsulated by a membrane of complex lipidic composition, right?

Not anymore! @JamesSaenz.bsky.social et al. show that a ‘minimal’ bacterial cell only needs 2 lipid species

#microNatComms #Microbiology #CellBiology #lipids

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Microbial species and intraspecies units exist and are maintained by ecological cohesiveness coupled to high homologous recombination - Nature Communications Microbial communities are predominantly composed of species and intraspecies units, but the mechanisms behind the formation and persistence of these units are unclear. Here, the authors provide experi...

Microbial species? OK, but... how?

Ecological cohesiveness, coupled to unbiased horizontal gene flow, may account for the observed species and intraspecies clusters
@ramonix.bsky.social @mpimarinemicrobio.bsky.social

#microNatComms #microbiology 🦠

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#microNatComms #microbiology

Infectious parvovirus B19 circulates in the blood coated with active host protease inhibitors - Nature Communications This study presents the first high-resolution structure of infectious parvovirus B19, purified from a patient. Two acute phase reactants, serpinA3, and ITIH4, bind to the capsid, suggesting B19V utili...

High-resolution structure of parvovirus B19, purified from a patient

#microNatComms #virology

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Infectious parvovirus B19 circulates in the blood coated with active host protease inhibitors
www.nature.com/articles/s41...

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The Southern Ocean hosts a unique and largely underexplored viral community

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Seasonal dynamics and diversity of Antarctic marine viruses reveal a novel viral seascape
www.nature.com/articles/s41...

#microNatComms #viromics

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Microbiology and infectious diseases This page highlights recent articles on all aspects of bacteriology, mycology, parasitology and virology, covering the biology of pathogens, host-pathogen ...

I'll try to post regularly (haha!) some recent (and awesome) #microbiology papers published in #NatureCommunications

I'll be using the hashtag #microNatComms

You can find the editors' highlights on this page:
www.nature.com/collections/...