Ablation of CCL17‐positive hippocampal neurons induces inflammation‐dependent epilepsy Ablation of CCL17-expressing hippocampal neurons induces spontaneous epileptic seizures accompanied by neurodegeneration, gliosis and behavioral changes. Inhibition of soluble TNF by XPro1595 applica...

Ablation of CCL17-positive hippocampal neurons induces inflammation-dependent epilepsy #Epilepsia #FoersterLab @unibonn.bsky.social #XPro1595; #astrogliosis; #diphtheria #toxin; #microgliosis; #neurodegeneration shorturl.at/j0BaF

#Microhaemorrhages are common . intranasal #SARSCoV2 infection caused #microgliosis, #tau #hyperphosphorylation & α-synuclein pathology in 🐹 cortex even without CNS infection. Notably, the pathology persisted beyond #viralpersistence which could have implications for #longCOVID & #neurodegeneration