Effectiveness of Schema Therapy versus Cognitive Behavioral Therapy versus Supportive Therapy for Depression in Inpatient and Day Clinic Settings: A Randomized Clinical Trial Schema therapy (ST) reduces depressive symptoms, but clinical trials have not investigated its effectiveness for patients suffering from severe forms of depression and high rates of comorbidities. The...

The presentation by @kopf-beck.bsky.social provides connections btw results of the OPTIMA trial
pmc.ncbi.nlm.nih.gov/articles/PMC...
(schema therapy in psychiatric care program showed #noninferiority compared to CBT)
onlinelibrary.wiley.com/doi/full/10....

and...

#SPRKrakow2025 #EMA #RCT

48616 - Design and analysis of noninferiority studies Equivalence testing is introduced and PROC POWER is illustrated for determining sample size for noninferiority studies. Noninferiority tests for proportions and means are conducted using PROC FREQ an...

#statstab #194 Design and analysis of noninferiority studies

Thoughts: Sometimes all you want to know is "is this new thing not worse than the previous one?". Enter noninferiority tests.

#noninferiority #equivalencetests #nhst #testing

support.sas.com/kb/48/616.html