Glad to contribute to this review on the knowns and unknowns on #Salinity tolerance of #freshwater #fish,
with oustanding collaborators, led by @canobarbacil.bsky.social #Limnology #Ecology #Biodiversity #Osmoregulation #Ichthyology #WaterQuality #InlandWaters #OpenAccess

M04.03.007 Anti-Diuretic Hormone Anti‑Diuretic Hormone (ADH), also known as vasopressin, is a crucial peptide hormone that regulates water balance, blood pressure, and osmolality by increasing renal water reabsorption and causing vasoconstriction.

#WaterBalance, #Osmoregulation & #BloodPressure #RAAS,
#Nephrology #Endocrinology: @NephJC, @Neph_SIM, @ASN_Kidney, @kidney_boy, @FreelyFilteredMD

When external salinity increases, euryhaline fish try to maintain constant internal osmotic pressures (homeostasis) by altering their osmoregulatory sub-PRN to intake more water and excrete excess ions. Above is a schematic highlighting some (not all) of this homeostatic response. Osmosensors in the gut, gills, and brain detect internal changes in osmotic pressure, which leads to a endocrine response. Highlighted here are two hormonal responses stemming from the Hypothalamus-Pituitary-Interrenal axis: (1) ACTH released from the pituitary stimulates the release of cortisol (CORT) from the interrenal into the bloodstream, and (2) GH is released into the bloodstream from the pituitary. CORT and GH then bind to receptors in the gill, which triggers the hypo-osmoregulatory function of the gills: the proliferation of saltwater type ionocytes. These ionocytes then sense osmotic changes and excrete excess ions via ion transporters (see text for specifics). Hence, although the gill, brain, and gut form their own trans-organ sub-PRN, each organ itself also contains a smaller sub-PRN, and communication between the tissues is facilitated by the neuroendocrine system (connection between the brain and gill). Depending on the severity of the (salinity) stress and the makeup of the individual’s sub-PRNs, which is determined by the individual’s genotype to phenotype map, the fish will enter one of 4 zones of stress: Optimal, Pejus, Pessium, Lethal. These zones are described in detail in Fig. 2, and the behavioral consequences are highlighted here. Depending on the zone, an individual will either engage in: fitness increasing tasks like reproduction (baby fish), behavioral regulation to reduce stress (circular arrows), or fleeing the environment (left pointing fish). Artwork by Emily Tarnawa..."

ICB
A Systems Approach to #Homeostasis:
What Euryhaline #Fish #Teach Us About #Organismal #Stress Responses
Mauro, Velotta @cam-g.bsky.social

doi.org/10.1093/icb/...

#biology #physiology #osmoregulation #ecology #endocrinology #evolutionary #science

Heading to Biomatter: From Cytoskeleton to Embryo in Arolla?
Don’t miss our PhD student @prajwal08.bsky.social at poster #44! Come hear about his cool work on #osmoregulation during #embryogenesis.

#Arolla2025

Dr Noelia Lander reviews the structure of #cAMP compartments in #Trypanosoma #cruzi. #Contractile #Vacuole #Environmental #Sensing #Flagellar #Distal #Metacyclogenesis #Osmoregulation #Signaling #Microdomains

authors.elsevier.com/a/1lRke5Eb1x...

ICB A Systems Approach to #Homeostasis: What #Euryhaline #Fish Teach Us About Organismal #Stress Responses
Mauro, Velotta , @cam-g.bsky.social

doi.org/10.1093/icb/...
#ecology #biology #physiology #osmoregulation #environment #evolution

Convenor Application Form Interested in one of our convenor vacancies? Apply here.

new Deputy Convenor for our Animal Osmoregulation Special Interest Group!

👉 Apply now
www.sebiology.org/special-inte...

📄 View role description
www.sebiology.org/special-inte...

📅 Deadline: 15 May 2025

#SEB #Osmoregulation