Protein palmitoylation and sphingolipid metabolism control regulated exocytosis in cytotoxic lymphocytes Protein palmitoylation and sphingolipid metabolism control lytic granule release in cytotoxic lymphocytes via membrane targeting of SNAP23.

Recently in #Science #Immunology: Kalinichenko, Huemer, @boztugk.bsky.social, & colleagues report than #sphingolipid #metabolism & protein #palmitoylation play critical roles in the killing of target cells by #cytotoxic #lymphocytes!

Insulin regulates lymphatic endothelial integrity via palmitoylation Lipid metabolism plays a critical role in lymphatic endothelial cell (LEC) development and vessel maintenance. Altered lipid metabolism is associated …

Our latest publication investigating the role of #palmitoylation in #lymphatic endothelial integrity.

Big shoutout to Silvia Gonzalez-Nieves, Simon GUIGNARD and Thi Nguyen for their incredible work and dedication. 👏👏

www.sciencedirect.com/science/arti...