Ist2 is a #phospholipid scramblase that links #lipid transport at the ER to organelle homeostasis, say Heitor Gobbi Sebinelli, Camille Syska, Hafez Razmazma, Luca Monticelli, Guillaume Lenoir, Alenka Čopič @umontpellier.bsky.social et al: rupress.org/jcb/article/...

#Biophysics #ER_literature

Sebinelli, Syska, Razmazma et al. @umontpellier.bsky.social show that the yeast protein Ist2, which localizes to ER–PM contact sites, possesses a #phospholipid scramblase activity in its ER-localized transmembrane domain that is important for several ER-related processes. rupress.org/jcb/article/...

Tumour interstitial fluid-enriched phosphoethanolamine suppresses T cell function - Nature Cell Biology Wang, Wilfahrt and colleagues show that phosphoethanolamine, a phospholipid intermediate, is enriched in tumour interstitial fluid and induces T cell dysfunction, in part by depleting diacylglycerol a...

☕Wang, Wilfahrt et al show that phosphoethanolamine, a #phospholipid intermediate, is enriched in #tumor interstitial fluid and induces T cell dysfunction, in part by depleting diacylglycerol and dampening T cell receptor signaling.
👉https://rdcu.be/ekqwI
go.nature.com/3YqG7Gq

Definition of phospholipid Explore the definition of the word "phospholipid" with example sentences, synonyms, and related terms to improve your English skills.

phospholipid
- Any of various compounds composed of fatty acids and phosphoric acid and a nitrogenous base; an important constituent of membranes

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#definition #phospholipid #meaning #english #ielts

Interferon‐inducible phospholipids govern IFITM3‐dependent endosomal antiviral immunity | The EMBO Journal image image The interferon‐induced transmembrane proteins (IFITM) can restrict entry of multiple viruses through mechanisms that are still elusive. This work shows that IFITM3‐dependent endosomal restriction of viral entry requires ...

I would like to start the week with an older post from the other side on our discovery that #PIP3 is an #IFN-inducible #phospholipid required for endosomal #IFITM3 #antiviral #immunity & can be harnessed to #boost restriction against #viruses such as #Omicron 🦠 👉🏻
www.embopress.org/action/oidcS...