We welcome you to read the interesting paper: TCEPVDB: Artificial Intelligence-Based Proteome-Wide Screening of Antigens and Linear T-Cell Epitopes in the Poxviruses and the Development of a Repository 🧬🖥️🥼
mdpi.com/2227-7382/13/4/58
#proteomes #proteomics #proteoform #vaccine #poxviruses #repository

Viral Reprogramming of Nucleotide Synthesis and Its Impact on Viral Infection Nucleotides are the building blocks of DNA and RNA. They also play essential roles in various other biological processes, including protein glycosylation, ribosome biogenesis, and cytoskeletal functi...

in various families of #RNA & #DNA 🦠 ( #herpesviruses, #poxviruses, #influenzaviruses & #SARSCoV2 & also discussing the signaling pathways as the regulatory mechanisms and highlight the gaps in understanding the mechanistic details

onlinelibrary.wiley.com/doi/full/10....

A poxvirus ankyrin protein LSDV012 inhibits IFIT1 in a host-species-specific manner by compromising its RNA binding ability Author summary In this study, we investigated the role of ankyrin repeat proteins in the Lumpy skin disease virus (LSDV), focusing specifically on LSDV012. Poxviruses, known for their large genome siz...

Important paper demonstrates host-species specific inhibition of IFIT1 by different #poxviruses.
A poxvirus ankyrin protein LSDV012 inhibits IFIT1 in a host-species-specific manner by compromising its RNA binding ability: dx.plos.org/10.1371/jour...

Hijacking the ribosome: New insights into how poxviruses boost protein production Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their own protein production, according to a study published in Cell Reports.

Hijacking the #ribosome: New insights into how #poxviruses boost #protein production.

#proteomics #cryoelectron_microscopy #knockout #RACK1 #RPLP2 #P-stalk

phys.org/news/2025-01...