RT-QuIC reactivity across brain and peripheral organs is assessed in hamsters with scrapie infection.
doi.org/10.15212/ZOO...
#RTQuIC #Scrapie #PrionDisease #Diagnostics

Daniel Ojeda-Juarez, PhD - CJD Foundation Grant Title: Characterizing Early Synaptic Dysfunction in Human Prion Disease Using a Human iPSC-Derived Neuronal Model Location: University of California, San Diego Grant Year: 2026

Using stem cell technology, we’re determining how neuronal hyperactivity causes vital communication bridges (synapses) to deteriorate. Our goal is to identify the window to protect the brain before permanent damage occurs.

Learn more: cjdfoundation.org/daniel-ojeda...

#CJD #PrionDisease

@cidrap.bsky.social should have included what "#CWD" is
#CWD = #ChronicWastingDisease = #CJD = Creutzfeldt-Jakob Disease= #MadCowDisease = #PrionDisease Prions aren't bacteria or viruses & can't be killed by cleaning. It lives in & damages the brain. There is no cure. (See below)

The mechanisms in #priondisease pathogenesis involves templated polymerization of normal host prion protein (PrPC) into disease-associated forms (PrPSc) https://www.nature.c

Eric Minikel and Sonia Vallabh pose for a photo in their lab at the Broad Institute. Credit: Broad Institute.

Light microscopy image of brain tissue showing neuronal loss in the brain of a patient with Creutzfeldt–Jakob disease. Credit: Sherif Zaki and Wun–Ju Shieh via Wikimedia Commons.

Eric Minikel & Sonia Vallabh, a husband-and-wife team, describe themselves as “on a lifelong quest to prevent #priondisease.” They run a lab at the @broadinstitute.org, studying prion disease, a rare, aggressive & fatal neurodegenerative disease: ow.ly/UoFm50WrvlA.
#RareDiseaseAwareness #ASBMBToday

Membrane-anchored PrPSc is the trigger for prion synaptotoxicity
Gatdula, J. R. P., Harris, D. A. et al.
Paper
Details
#PrionDisease #Neurodegeneration #Synaptotoxicity

Summer 2025 cover of ASBMB's member magazine ASBMB Today featuring prion protein fibrils. Credit: National Institutes of Health. Text reads biochemical innovations for rare diseases.

📬The summer issue of ASBMB Today is out now! Check your mailbox or read online.
In this issue, we spotlight groundbreaking rare disease research, showcase new trends in undergraduate education & address the role of #AI in the classroom.
ow.ly/Ubj350Wqfcr.
#PrionDisease #LaforaDisease

US woman dies from prion disease — after being given an infected injection 50 years earlier The patient was unknowingly infected with an abnormal protein that causes a rare, fatal neurological disease with no treatment.

US woman dies from prion disease — after being given an infected injection 50 years earlier #Science #HealthandMedicine #InfectiousDiseases #PrionDisease #HealthNews #MedicalResearch
purescience.news/article?id=4...

Divalent siRNA for prion disease

www.biorxiv.org/content/10.1101/2024.12....

#neurodegeneration #priondisease

#FluA has me laid out. At Urgent Care we all sounded the same. Hoarse corpse voices, croupy coughs. Dreamed on NyQuil, Sudafed, and Benadryl about a #priondisease you could see as it stalked you — like a flower floating on the air. Anyway, I think we’ll miss regulations.

#fda #who #callyoursenators

Cursed Ground It is 0730 and I have prions on my mind again. Have I posted about this particular interest before? Probably, somewhere, I’m not going to dig it up. On this morning, I’ve got prions on …

I've got prions on the mind once more.
#horrorwriter #shortfiction #science #priondisease
icarusblake.wordpress.com/2025/01/16/c...

I guess my question is “why am I at all surprised?” 😂

#carnivorediet meatclowns have proven themselves to be the most gullible rubes on the internet 🤡 🥩 🎪

#meatcult #atherosclerosis #priondisease #creutzfeldt-jacob

Very excited to see this work preprinted after seeing Sonia present it last year @rti-umasschan.bsky.social. Here’s hoping #RNAtherapeutics open new doors for treating #PrionDisease. Congrats to all involved in the Vallabh/Minikel and Khvorova labs, and beyond!

#RNASky #ScienceHeroes

Covid vaccines and mad cow disease / prion disease There are reports and scientific studies confirming the covid injections can lead to prion disease and mad cow disease.

Ususally it takes decades but with the covid injections only a few months to die of mad cow disease from these injected experiments. They cause some form of brain damage all the time.

#madcowdisease #priondisease #covidvaccine #braindamage

patientmaktpatientcv.substack.com/p/covid-vacc...

Fascinated with prion disease for a long time now. Anyone else on here? #books #priondisease

Two Wyoming Hunters 'Become First Americans To Die From Zombie Deer Disease' Two Wyoming hunters have just become the first Americans to die from what is known as "zombie deer" disease.

#priondisease
www.themix.net/2024/04/two-...

Two Hunters Died of Rare Prion Disease. Doctors Suspect a First-of-Its Kind Deer Transmission Two recent cases of prion disease in the U.S. may have been caused by contaminated deer meat, though the connection is still unproven.

Two Hunters Died of Rare #PrionDisease. Doctors Suspect a First-of-Its Kind Deer Transmission
Two recent cases of prion disease in the U.S. may have been caused by contaminated deer meat, though the connection is still unproven.
gizmodo.com/chronic-wast... via @gizmodo

MedSky🧪 #IDSky #NeuroSky
There are 3 forms of attack
Cases of #priondisease acquired from eating infected beef made headlines, but less than 1% of pd is caused by external sources of infection, including surgeries and blood transfusions. The vast majority is sporadic #CreutzfeldtJakobdisease