Daniel Ojeda-Juarez, PhD - CJD Foundation Grant Title: Characterizing Early Synaptic Dysfunction in Human Prion Disease Using a Human iPSC-Derived Neuronal Model Location: University of California, San Diego Grant Year: 2026

Using stem cell technology, we’re determining how neuronal hyperactivity causes vital communication bridges (synapses) to deteriorate. Our goal is to identify the window to protect the brain before permanent damage occurs.

Learn more: cjdfoundation.org/daniel-ojeda...

#CJD #PrionDisease

@cidrap.bsky.social should have included what "#CWD" is
#CWD = #ChronicWastingDisease = #CJD = Creutzfeldt-Jakob Disease= #MadCowDisease = #PrionDisease Prions aren't bacteria or viruses & can't be killed by cleaning. It lives in & damages the brain. There is no cure. (See below)

The battle over Canada's mystery brain disease - BBC News A small Canadian province feared it had a mystery neurological illness on its hands. The search for answers set off a battle for the truth.

'The answer cannot be nothing': The battle over #Canada 's mystery #BrainDisease
www.bbc.com/news/article...
怖いよう〜。(;;)
#CreutzfeldtJakobDisease #CJD

A wolf in synuclein clothing: Creutzfeldt-Jakob disease disguised as MSA Rapidly progressing neurological disease should immediately signal a possible prion disorder. Learn key diagnostic clues to distinguish Creutzfeldt-Jakob disease from mimics like multiple system…

#MedCase - Rapidly progressing neurological disease should immediately signal a possible #prion disorder.

Learn key diagnostic clues to distinguish Creutzfeldt-Jakob disease from mimics like multiple system atrophy.

👉 buff.ly/FIsDTyz

#NeuroSky #CJD

Case Report: #CJD and #diagnosis #challenges: case report and evidence synthesis

Case Report: #CJD and #diagnosis #challenges: case report and evidence synthesis, etidiohnew.blogspot.com/2026/01/case...

CSF RT-QuIC detects #CJD
by amplifying tiny amounts of misfolded prion protein (PrPSc) in CSF into detectable amyloid fibrils, using constant shaking (quaking) & fluorescence dye (Thioflavin T) to monitor aggregation in real-time, providing high sensitivity (90-92%) & specificity (near 100%)

Sporadic Creutzfeldt-Jakob disease: Real-Time Quaking-Induced Conversion (RT-QuIC) assay represents a major diagnostic advance Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare and fatal neurodegenerative disorder with an incidence of 1.5 to 2 cases per million population/year. The disease is caused by a proteinaceous infectious agent, named prion (or PrPSc), which arises ...

CSF Real-Time Quaking-Induced Conversion (RT-QuIC) #CJD pmc.ncbi.nlm.nih.gov/articles/PMC...

I hope these guys all get familiar with #CJD
Such narcissists!

While no one was watching: Tenuous status of CDC prion unit, risk of CWD to people worry scientists

Terrifying #CJD

While no one was watching: Tenuous status of CDC prion unit, risk of #CWD to people worry scientists: www.cidrap.umn.edu/chronic-wast...

Ehrenamtspreis-Nominierung: AG Friedhof Hochstraße Braunschweig Schülerinnen und Schüler kümmern sich ehrenamtlich um die Gräber von Zwangsarbeitern auf dem Friedhof Hochstraße.

Jede Stimme zählt - AG Hochstraße ist für den NDR Ehrenamtspreis 2025 nominiert! 🙌

Die Schüler:innen pflegen den historischen Friedhof und halten die Erinnerung an Zwangsarbeiter:innen wach.
Jetzt abstimmen:
www.ndr.de/ndr1niedersa...

#Ehrenamt #Braunschweig #Erinnerungskultur #Schule #NDR #CJD

This is the face of #CJD, an untreatable and incurable #raredisease. Today is #InternationalCJDDay. We lost mom at the young age of 61 to #CJD. This disease ravages 1 in 1 million. #raisingawareness

🧬 The Cure CJD Campaign launches an international fundraising effort to raise £9 million for Phase II clinical trial of #PRN100 — the most promising treatment ever developed for prion diseases. Read the full Press Release: curecjd.org/wp-content/u...

#CJD #PrionDiseases #PRN100

With your work with Alzheimer's, have you found many deaths later attributed to #CJD? CJD numbers are rising.

I started studying about mad cow prions about 15 yrs ago, and its leap into wildlife.. and then people with #CJD. If is isnt one thing going to get us, it will be the other. Humans are pathetic. Animals do not deserve what we do to them.

Worrying that activities that endanger the public can lead to such derisory fines #MadCowDisease #CJD

www.youtube.com/watch?v=FQ_A... #ena #cjd 😍

530: Robert Klitzman | Person Place Thing with Randy Cohen Person Place Thing with Randy Cohen is an interview show based on this idea: people are particularly engaging when they speak not directly about themselves but about something they care about. Guests ...

Catch my conversation with @randycohen48.bsky.social for Person Place Thing here: personplacething.org/530-robert-k...

#healthcare #spirituality #religion #chaplains #newguinea #prion #kuru #Creutzfeldt-jakobdisease #cjd #neuro #stoneage #bioethics

Rare, 100% fatal brain disease strikes 3 people in Oregon Hood River County in Oregon reported three cases of Creutzfeldt-Jakob disease, a rare human brain disease very similar to "mad cow."

UH OH, Hood River!

#CreutzfeldtJakobDisease, #CJD, #ChronicWastingDisease, #CWD, #MadCowDisease

www.livescience.com/health/virus...

The Unfolding Story of Protein Misfolding Causing Alzheimer Disease in Recipients of Human Pituitary Growth Hormone Abstract. Human growth hormone (hGH) has been in clinical use for children with GH deficiency (GHD) since the late 1950s. The original formulations were co

The unfolding story of protein misfolding causing #Alzheimer disease in recipients of human #pituitary #GrowthHormone. Featured article in #JES #OpenAccess
#CJD #prions
@endocrinesociety.bsky.social
doi.org/10.1210/jend...

@elizabethjacobs.bsky.social #CJD is also contagious, can be passed from patient to patient on surgical instruments, as it survives usual sterilizing procedures.

Burning pyres nightmare unlocked 🔥🧠

“CJD (Creutzfeldt–Jakob disease) is a rapidly progressive central nervous system disorder caused by misfolded prion proteins. CWD, a prion
disease prevalent in N. American deer, has raised concerns…possible link”

#speirgorm #spéirghorm #CJD #Neurology #Prions

1. In human #CJD and #GSS frontal cortex, we identify an increase in the immediate early gene, Arc/Arg3.1, suggestive of neuronal hyperactivity.

Not only is there still no cure for CJD, there is no medicine or procedure to slow the devastating process. Please take bird flu seriously. #bird flu #CJD #mad cow disease #avian influenza

Mood Alterations in the Prodromal Phase of Sporadic Creutzfeldt-Jakob Disease This case-control study investigates prescription medication use in patients with sporadic Creutzfeldt-Jakob disease before clinical onset of the disease compared with that of control patients.

Breakthrough in #Creutzfeldt-Jakob research: Medical University of #Vienna identifies mood changes as potential early warning sign. Study shows: #CJD patients received #antidepressants 3x more often years before diagnosis. #Neurology #Research
jamanetwork.com/journals/jam...

My grandmother died of CJD and it's the reason none of her 4 living children or 12 grandchildren or 7 biological great-grandchildren can donate blood 😞 #CJD #dementia #awareness

What’s your favorite fantasy? Let’s make it a reality. 😈 #AmateurHour #JOI #Niteflirt #CJD 📞

No, the sensible thing is to cut out the middlebeast and turn them over to Soylent.
#CJD