Time for an update? Research #exome #sequencing can achieve up to 95% sensitivity in detecting #PKD1 variants, rivaling traditional methods. bit.ly/4cVfb9T #AKPKD #Pseudogenes

#Pseudogenes aren’t always silent 🧬 RPS27AP5, once considered non-functional, produces a #ubiquitin variant (UbP5) and #ribosomal #protein variant (S27aP5) that alters #mRNA association, adding evidence for ribosome diversity 👏
https://ow.ly/hsNn50Yh11e

This review explores various #cancer #DrugResistance mechanisms, the structure and functions of #Pseudogenes, and the role of pseudogene-derived lncRNAs in promoting drug-resistance in different cancers. #medsky

#OpenAccess:

LR-WGS tell us to not engage on stigmatized discourses of the spectrum. A lot to do undercover, metabolomics & signaling wise have sampling challenges.
Deglamorize rights to public mental health. Deep respect to informed misdiagnosis that set limits to clinical abuses. #transposons #pseudogenes :)

This review explores various #cancer #DrugResistance mechanisms, the structure and functions of #Pseudogenes, and the role of pseudogene-derived lncRNAs in promoting drug-resistance in different cancers. #medsky

#OpenAccess:
www.sciencedirect.com/science/arti...