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Overactive Runx1 Gene Triggers Early Disc Degeneration Linked to Aging BUFFALO, NY — October 17, 2025 — A new #research paper was #published in Volume 17, Issue 9 of Aging-US on September 8, 2025, titled, “Runx1 overexpression induces early onset of intervertebral disc d

🎧 Listen to our #pressrelease about the #researchpaper, "Runx1 overexpression induces early onset of intervertebral disc degeneration."

soundcloud.com/aging-us/ove...

#aging #podcast #audio #SoundCloud #research #TrendingWithImpact #openaccess #journal #publishing #press #runx1

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Overactive Runx1 Gene Triggers Early Disc Degeneration Linked to Aging | Aging Taken together, these findings reveal a novel role of Runx1 in maintaining disc health and regulating age-related degenerative processes."Click here to listen to the press releaseBUFFALO, NY — Oc...

📈 #TrendingWithImpact:
This #research paper was #published in Volume 17, Issue 9, titled "Runx1 overexpression induces early onset of intervertebral disc degeneration."

#PressRelease ⬇️
www.aging-us.com/news-room/ov...

#aging #press #runx1 #cellularsenescence #oa #publishing #journal

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📈 #TrendingWithImpact:
A new #research paper was #published on September 8, titled “Runx1 overexpression induces early onset of intervertebral disc degeneration.”

🔗 doi.org/10.18632/agi...

#aging #quote #cellularsenescence #runx1 #openaccess #publishing

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🎥 #AgingShort:
Abstract #video about this #research paper, titled “Runx1 overexpression induces early onset of intervertebral disc degeneration.”

🔗 doi.org/10.18632/agi...

#aging #TrendingWithImpact #cellularsenescence #runx1 #skeletalsystem #openaccess #publishing

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Healthcare providers: please encourage your #RUNX1 patients to connect with our supportive community by contacting Amanda Eggen at aeggen@runx1-fpd.org or through our website: www.runx1-fpd.org.

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DEADLINE: NEXT MONDAY
Submit your abstract for the 9th Annual Virtual #RUNX1 Scientific Conference (Sept 9–10, 2025). Share your work with the global RUNX1-FPD research community! Details here: runx1researchprogram.org/xRUNX1SciCon...

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June newsletter highlights:
• $50K+ raised to support RUNX1-FPD clinical trial access
• Tissue Bank now open at @upenn.edu & accepting #RUNX1 patient samples
• 2026 Scientific Conference early bird registration open thru Aug 5
• 2025 abstract submissions now open

🔗 www.runx1-fpd.org/rrp-newsletter

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Abstract submissions are now open for the 9th Annual Virtual #RUNX1 Scientific Conference, happening September 9–10, 2025.
Share your latest research with the global RUNX1-FPD community.
Submission guidelines: runx1researchprogram.org/xRUNX1SciCon...

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Now accepting abstract submissions for the 9th Annual Virtual #RUNX1 Scientific Conference on September 9th and 10th, 2025. Share your work with the international RUNX1-FPD community! Find details and guidelines here:
runx1researchprogram.org/bsRUNX1SciCo...

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ATTN #RUNX1 Clinicians: RRP offers specialized resources, peer groups, educational events & research opportunities specifically for RUNX1-FPD patients. Please refer your patients directly to Amanda Eggen (aeggen@runx1-fpd.org) & share our site: runx1-fpd.org.

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RRP Webinar Tomorrow!

Can stem cell diversity be enhanced pharmacologically? Join Dr. @leonard_zon on Tuesday, May 6th at 11 a.m. PDT for a deep dive into #RUNX1, ELF1, and a new mechanism for HSC expansion.

Register today: runx1researchprogram.org/tRRPZonMay2025

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RRP Webinar in One Week!

Can we pharmacologically expand stem cell clones in vivo? Dr. @leonard_zon presents new evidence on #RUNX1, ELF1, and Ro5-3335 in our next RRP Research Webinar on Tuesday, May 6th at 11 a.m. PDT.

Register now: runx1researchprogram.org/tRRPZonMay2025

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What if we could enhance stem cell diversity with a drug?

Dr. Leonard Zon shares new insights into hematopoietic stem cell expansion and the role of #RUNX1 in our upcoming RRP webinar on Tuesday, May 6 at 11 a.m. PDT.

Register now: runx1researchprogram.org/tRRPZonMay2025

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Join us on Tuesday, May 6 at 11 a.m. PDT to learn how #RUNX1 binding partners shape hematopoietic stem cell fate. Dr. Leonard Zon will share his team’s latest findings on ELF1, Ro5-3335, and increasing clonal diversity.

Register here: runx1researchprogram.org/tRRPZonMay2025

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New discovery from Fabiola Del Carpio-Cano on the role of RUNX1 regulates platelet-megakaryocyte F13A1 expression, impacting clot stabilization.

Read the full study: www.rpthjournal.org/article/S247...

#platelets #RUNX1

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Join us on April 1st at 11 am PT for a webinar with Dr. Kristy Stengel on how transcription factors fine-tune hematopoietic gene expression. Learn about RUNX1 regulation and participate in the Q&A.

🔗 Register here: rebrand.ly/RRPWebinarAp...

#Genomics #Hematology #RUNX1 #GeneExpression

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Enrollment in our study is absolutely free. For those who can join us in Bethesda at the NIH we are able to provide transportation and lodging. And we cover the costs of all testing (which is only to your level of comfort and desired involvement) #RUNX1

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RUNX1 Research Program RUNX1 Research Program supports groundbreaking research aimed at cancer prevention and intervention for individuals with the rare disease RUNX1 familial platelet disorder (RUNX1-FPD), which increases ...

We also encourage all of our study participants and their families to connect with RUNX1 Research Program where they will find an amazing community of caring providers, researchers, and most importantly other people also on their RUNX1 Journeys. #RUNX1 #HemeSky #Platelets

www.runx1-fpd.org

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NIH RUNX1-FPD Clinical Research Study A study where both genotypic (individual genetics) and phenotypic (individual disease characteristics) patient data would be analyzed using advanced data-analytics programs to derive meaningful associ...

If you or someone you know or provide care for has RUNX1 Familial Platelet Disorder, please reach out to the NHGRI RUNX1 Natural History Study. #HemeSky #RUNX1 #FPD

www.genome.gov/Current-NHGR...

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Diversity in research is essential for research equity and equipoise. This is important for treatment AND natural history studies. At NHGRI #RUNX1 Natural History Study we strive to learn about ALL people with FPDMM.

#ASH24 #HemeTwitter @ash-hematology.bsky.social

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Shameless shoutout to the #RUNX1 Natural History Program of NHGRI as presented by Erica Bresciani. It’s my absolute pleasure to be a part of the program bringing together amazing patients and collaborators to study #RUNX1FPD #ASH24

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The scientific workshop on germline predisposition to hematologic malignancy and BMF is starting! Looks to be an exciting session with specific emphasis on #RUNX1 and #DDX41 @ash-hematology.bsky.social #ASH24

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