This study uses an ABE-based #sgRNA library to map over 1,000 functional #mutations that regulate PD-L1 and HLA-I expression, identifying SETD2_Y1666, which influences #ImmuneEvasion & anti-PD-1/PD-L1 therapy responses. @pku1898.bsky.social

#STTT #OpenAccess: doi.org/10.1038/s413...

Advances in CRISPR/Cas9-Based Gene Editing Technology in Mosquitoes As global warming increases, mosquito activity areas are expanding, alongside changes in the natural environment and the misuse of insecticides, thus further increasing mosquito resistance and exposin...

Advances in CRISPR/Cas9-Based Gene Editing Technology in Mosquitoes.

Read More: tinyurl.com/3du4vx9k

#Mosquito #sgRNA #CRISPRCas9 #Geneediting #Zoonoses #Zoonotics #Zoonosis @scienceopen.bsky.social

Advances in CRISPR/Cas9-Based Gene Editing Technology in Mosquitoes As global warming increases, mosquito activity areas are expanding, alongside changes in the natural environment and the misuse of insecticides, thus further increasing mosquito resistance and exposin...

Advances in #CRISPR/#Cas9-Based Gene Editing Technology in #Mosquitoes.

Read More: tinyurl.com/5zyu3xf3

#sgRNA #Zoonoses #Zoonosis #Zoonotics #ZoonoticDiseases @scienceopen.bsky.social

Cool!
#CRISPR #sgRNA #Folding