HIF1α gates tendon response to overload and drives tendinopathy independently of vascular recruitment HIF1α activation promotes tendinopathy, and its inhibition prevents overload-induced maladaptation, suggesting therapeutic potential.

Healthy tendons do not contain an extensive #vascular network, so why would I be interested? Well, vascular ingrowth is a hallmark of #tendinopathy! 👇 Look at what Greta discovered! #snedekerlab #debocklab

www.science.org/doi/10.1126/...