🧫 Carbonic anhydrases (CAs) are zinc-containing enzymes that help maintain cellular pH.

The isoform CA IX is overexpressed in hypoxic tumour environments, making it a particularly attractive target for new anticancer therapies. 1/4

#research #steroidchem #chemistry

👨‍🔬 As a young chemist, Pavel Kočovský began working at #IOCBPrague in the early 1970s, shortly after the 1968 occupation.

Under the supervision of Professors Černý and Šorm, he focused on #steroidchem and became one of the prominent figures in this field... 1/4