#SMYD3 methylates #cMyc to sustain #ColorectalCancer stem cell self‑renewal and #metastasis; inhibition of SMYD3 reduces #clonogenicity, #tumorigenicity, and dissemination, highlighting the SMYD3/c‑MYC axis as a therapeutic target for CRC.

#CoverPage #STTT: doi.org/10.1038/s413...