Retreatment With Nirmatrelvir/Ritonavir Following Return of COVID-19 Symptoms and SARS-CoV-2 Positivity Repeated nirmatrelvir/ritonavir treatment in participants with COVID-19 rebound was safe and well tolerated. In this group of participants, there was no cl

#Medsky🧪 #IDsky #immunosky #virosky #publichealth @cidjournal.bsky.social A repeated 5 d course of #paxlovid was safe & well tolerated & associated with a faster decline in #viralRNA levels. However there was no clear benefit of retreatment ➡️ rebound was transient & did not lead to severe #COVID

Pp1ab is a large non-structural protein in #SARSCoV2, crucial for #viralreplication & transcription. It is unique to #SARSCoV2 & not found in uninfected human cells. After being translated from the #viralRNA, Pp1ab is cleaved into 16 nonstructural proteins (nsps)

Terminal Loop Sequences in Viral Double-Stranded RNAs Modulate RIG-I Signaling
Gnazzo, V., Hackbart, M. et al.
Paper
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#RIGISignaling #ViralRNA #ImmuneResponse

Next-Gen Fluorosensor Detects Viral RNA in Real Time A new functionalized fluorosensor detects enteroviral RNA with high sensitivity in real time. It marks a major step in safer, more effective viral diagnostics. In a notable breakthrough, researchers at...

Next-Gen Fluorosensor Detects Viral RNA in Real Time #Science #HealthandMedicine #InfectiousDiseases #Fluoresensor #ViralRNA #HealthTech

Exploring the expanding universe of host-virus interactions mediated by viral RNA Viral RNA (vRNA) is a central molecule in viral infection; however, its interactions with the host cell remain largely unknown. The emergence of new methods now enables the comprehensive identificatio...

#MedSky🧪#IDSky #ImmunoSky Overview the host-🦠 interactions mediated by #viralRNA & the importance of vRNA in regulating protein function through riboregulation & Uncovering the vRNA #interactome

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