and chimeric antigen receptor T-cell ( #CARTcell ) therapy, are at an increased risk of prolonged #viralshedding, #viralrebound, and persisting infection. This subgroup represents a major clinical challenge,

2/7 The crisis began quietly: H5N1 was first introduced to cattle populations in late 2023, but wasn't identified until March 2024 when scientists investigated dramatically reduced milk production.

Unlike typical flu, H5N1 in cattle produces EXTREMELY HIGH viral shedding in milk.
#ViralShedding

3/5 Disease was moderate but not lethal: Ferrets had fever, lethargy, sneezing, nasal discharge and 9.8% weight loss but all survived 21 days. Virus primarily in respiratory tract with limited spread to brain/GI tissues. Peak viral shedding 4.7-5.4 log₁₀ PFU/mL.
#ViralShedding #DiseaseSeverity

5/8 Genetic archaeology reveals D1.1's Frankenstein origins: four segments mixing Eurasian and North American lineages. Its unique neuraminidase segment appeared for the first time in this British Columbia clade, possibly increasing viral shedding.
#GeneticOrigins #Neuraminidase #ViralShedding

Dr Evonne T Curran NursD 💙🇺🇦 on X: "Could it be aerosols of poo.... https://t.co/GQPzVM7wsS" / X Could it be aerosols of poo.... https://t.co/GQPzVM7wsS

#viralshedding #covid #virus #longCovid #fecal #poop
💩 🚽 🚻

Image @EvonneTCurran at x.com/EvonneTCurra...

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs Study demonstrates that a novel prime/boost vaccination protocol using live-attenuated influenza vaccines effectively induces strong immune responses in pigs, offering a promising approach for future ...

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs 🐷💉🔬 news-medical.net/news/2024081... #Influenza #Vaccine #ImmuneResponse #LAIV #PigModel #PrimeBoost #ViralShedding #Immunology #HerdImmunity