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Posts by Christine Rabinak, PhD, MBA

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| IDR | Dove Medical Press We aimed to investigate the effectiveness and safety of daptomycin in obese patients using AdjBW compared to those in obese and non-obese patients using ABW

Study shows daptomycin dosing using adjusted body weight in obese patients performs similarly to traditional dosing—supporting more tailored antibiotic strategies.

WSU EACPHS #InfectiousDiseases #Pharmacotherapy

doi.org/10.2147/idr....

3 weeks ago 0 0 0 0

New findings show STEAP4 plays a key role in liver recovery after acetaminophen injury by maintaining lysosomal iron balance and function—pointing to new treatment strategies.

WSU EACPHS #LiverResearch #TranslationalScience

doi.org/10.1097/hep....

3 weeks ago 0 0 0 0
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Developing and Evaluating Stable Microemulsion Systems for Potential Intranasal and Transdermal Application of Omeprazole - AAPS PharmSciTech Omeprazole is the first in a class medication that inhibits gastric secretion. However, it has a low stability, low bioavailability, and a short half-life after peroral administration. In the current ...

New publication featuring WSU EACPHS in AAPS PharmSciTech.

The study explores microemulsion systems that improve omeprazole delivery through intranasal and transdermal routes.

doi.org/10.1208/s122...

#DrugDelivery #Pharmaceutics #Nanomedicine

1 month ago 0 0 0 0
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New study featuring WSU EACPHS examines how psychoactive substances relate to cognitive function in people with multiple sclerosis. Caffeine was linked to short-term cognitive benefits, while cannabis/alcohol were associated with worse cognitive outcomes.

doi.org/10.1016/j.ap...

#MultipleSclerosis

1 month ago 2 0 0 0

New research from WSU EACPHS shows that 12 weeks of albuterol treatment improved pulmonary function in people living with chronic spinal cord injury.

Read it here: 10.1016/j.apmr.2026.01.013

#SpinalCordInjury #RehabilitationScience #RespiratoryHealth #WayneState

1 month ago 0 0 0 0

Congrats to WSU EACPHS researchers on their new paper in Arch Phys Med Rehabil exploring how machine learning + wearable devices can advance spinal cord injury research and patient care.

Read more: 10.1016/j.apmr.2025.09.025

#SpinalCordInjury #MachineLearning #Wearables #RehabilitationScience

1 month ago 2 1 0 0
The Human Side of Lab Leadership Research laboratories are complex social environments in which scientific discovery depends not only on technical expertise but also on effective leadership, mentorship, communication, and team functi...

Running a research lab is about leading people.

I created a free toolkit on the human side of lab leadership—covering hiring, mentoring, conflict navigation, lab culture, and performance management.

Open access: doi.org/10.5281/zeno...

#TeamScience #AcademicLeadership

1 month ago 2 3 0 0

As a neuroscientist who runs clinical trials—and someone living with metastatic breast cancer—I’m interested in collaborating with research teams as a patient research advocate.

Scientific + lived experience perspectives matter.

#PatientAdvocacy #ClinicalTrials #MetastaticBreastCancer

1 month ago 2 0 0 0
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Launching Your First Research Lab: Practical Guidance on Planning Your Research Program, Building a Team, and Launching a Sustainable Lab Starting an independent research lab is one of the most significant transitions in an academic career, yet many scientists receive little formal training in the practical aspects of launching and mana...

The first time you start a research lab, there’s no manual.

So I made one.

A practical toolkit for postdocs and early-career faculty launching their first lab: hiring, startup planning, collaborations, and building a sustainable research program.

zenodo.org/records/1888...

#research #postdoc

1 month ago 8 2 1 0
JCI - Genetic disruption of mitochondrial dynamics and stasis leads to liver injury and tumorigenesis

New research from WSU EACPHS shows that disruption of mitochondrial dynamics can trigger liver injury and tumor development through mitochondrial stress and inflammatory signaling.

#LiverDisease #CancerResearch

doi.org/10.1172/jci1...

1 month ago 4 1 0 0
Implementation of SARS-CoV-2 genomic surveillance during the COVID-19 pandemic through an academic–public health collaboration in southeast Michigan - Scientific Reports Scientific Reports - Implementation of SARS-CoV-2 genomic surveillance during the COVID-19 pandemic through an academic–public health collaboration in southeast Michigan

New research from WSU EACPHS highlights how an academic–public health partnership built a genomic surveillance pipeline to track SARS-CoV-2 variants across Southeast Michigan and support pandemic response efforts.

#PublicHealth #Genomics #COVID19

doi.org/10.1038/s415...

1 month ago 0 1 0 0
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Aspirin Deprescribing Interventions for Primary Prevention: A Systematic Review and Proposed Guidance for Deprescribing Recent literature indicates that the benefits of aspirin use for primary prevention of atherosclerotic cardiovascular disease (ASCVD) may be equivocal to the risk. This has resulted in several organi....

New research from WSU EACPHS reviews strategies to deprescribe aspirin used for primary prevention of cardiovascular disease and proposes an evidence-informed algorithm to guide clinical decision-making.

#PharmacyResearch

doi.org/10.1002/phar...

1 month ago 0 0 0 0

Study shows D-512 protects dopaminergic cells from rotenone-induced oxidative stress and mitochondrial dysfunction — supporting its potential in Parkinson’s disease.

Research from WSU EACPHS.

#ParkinsonsDisease #Neurodegeneration

doi.org/10.3390/jpm1...

2 months ago 3 1 0 0
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EBPS2023 special issue: Stress, trauma and cannabinoids - Psychopharmacology Psychopharmacology -

Excited to share the Psychopharm Special Issue on Stress, Trauma & Cannabinoids 14 papers examining how the endocannabinoid system shapes stress & trauma responses.

Guest edited with @connorhaggarty.bsky.social, @mayoonthebrain.bsky.social & Christelle Baunez.

link.springer.com/article/10.1...

2 months ago 8 6 0 0
Sage Journals: Discover world-class research Subscription and open access journals from Sage, the world's leading independent academic publisher.

Study shows gabapentinoids are associated with increased respiratory depression risk in hospitalized CKD patients — highlighting need for careful dosing and monitoring.

Research from WSU EACPHS.

#MedicationSafety #ChronicKidneyDisease

doi.org/10.1177/1060...

2 months ago 0 0 0 0
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Study shows the PNPLA3 148M variant exacerbates alcohol-induced liver injury and tumorigenesis — activating oncogenic pathways and impairing detoxification.

Research from WSU EACPHS.

#HepatocellularCarcinoma #LiverDisease

doi.org/10.1016/j.aj...

2 months ago 0 0 0 0
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Clinical efficacy and safety of eravacycline for the treatment of enterococcal infections: a subpopulation analysis - BMC Infectious Diseases BMC Infectious Diseases - Infections due to Enterococcus faecalis and Enterococcus faecium are common in the hospital setting and carry a high risk for morbidity and mortality. Furthermore, the...

Subpopulation analysis shows eravacycline achieved 77% clinical cure in enterococcal infections, nearly half VRE, with favorable safety.

Research from WSU EACPHS.

#AntimicrobialResistance #InfectiousDisease

link.springer.com/article/10.1...

2 months ago 0 0 0 0

Bile acid analogs targeting C. difficile spore germination safely altered bile acid homeostasis in vivo — supporting prophylactic development.

Research from WSU EACPHS.

#ClostridioidesDifficile #TranslationalScience

doi.org/10.3390/biom...

2 months ago 0 0 0 0
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Modified OPAT regimens in MDRO infections are associated with higher costs, discharge delays & prolonged LOS, with opportunities for oral-switch therapy.

Research from WSU EACPHS.

#AntimicrobialStewardship #TransitionsOfCare

doi.org/10.1093/ofid...

2 months ago 0 0 0 0
Sage Journals: Discover world-class research Subscription and open access journals from Sage, the world's leading independent academic publisher.

Backward walking speed strongly predicts daily step goal achievement in people with MS — offering a practical clinical mobility measure.

Research from WSU EACPHS.

#MultipleSclerosis #PhysicalActivity

doi.org/10.1177/1545...

2 months ago 0 0 0 0
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A stability-indicating RP-HPLC method for the simultaneous quantification of brimonidine tartrate and timolol maleate in bulk drug substances and pharmaceutical dosage forms - Scientific Reports Scientific Reports - A stability-indicating RP-HPLC method for the simultaneous quantification of brimonidine tartrate and timolol maleate in bulk drug substances and pharmaceutical dosage forms

Validated stability-indicating RP-HPLC method for simultaneous quantification of brimonidine tartrate & timolol maleate — supporting quality control and greener analytical practices.

Research from WSU EACPHS.

#AnalyticalChemistry #PharmaceuticalSciences

www.nature.com/articles/s41...

2 months ago 0 0 0 0
Implementation of an interruptive electronic health record alert improves optimal antibiotic prescribing in ambulatory patients with acute bacterial sinusitis: a quasi-experiment | Antimicrobial Stewa... Implementation of an interruptive electronic health record alert improves optimal antibiotic prescribing in ambulatory patients with acute bacterial sinusitis: a quasi-experiment - Volume 6 Issue 1

An interruptive EHR alert significantly improved optimal antibiotic prescribing for acute bacterial sinusitis (7% ➡️ 30%).

Outpatient stewardship innovation from WSU EACPHS.

#AntimicrobialStewardship #DigitalHealth

doi.org/10.1017/ash....

2 months ago 0 0 0 0
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New framework (IDEAL-R) provides guidance for evaluating the educational impact and sustainability of OSCEs in pharmacy curricula.

Education scholarship from WSU EACPHS.

#PharmacyEducation #HealthProfessionsEducation
doi.org/10.1016/j.aj...

2 months ago 0 0 0 0
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Daily EMA data show dynamic, bidirectional relationships between psychoactive substance use and symptoms in people with MS — improving understanding of real-world symptom regulation.

Research from WSU EACPHS.

#MultipleSclerosis #MSResearch
doi.org/10.1016/j.ap...

2 months ago 0 0 0 0
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Implementation of a Protocol With a Shortened Vancomycin Prophylaxis Duration is Associated With Reduced Acute Kidney Injury in Lung Transplant Recipients: A Quasi‐Experimental Study We evaluated implementation of a shortened post-operative vancomycin prophylaxis duration protocol on acute kidney injury (AKI) in lung transplant recipients. The intervention, modifying vancomycin (...

A shortened 72-hour vancomycin prophylaxis protocol in lung transplant recipients was associated with lower odds of acute kidney injury — with similar infectious outcomes.

Research from WSU EACPHS.

#AntimicrobialStewardship #TransplantMedicine

doi.org/10.1111/tid....

2 months ago 1 1 0 0
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Novel 5,6-fused heterocycle cholate derivatives inhibited C. difficile spore germination — and one compound prevented infection in a murine model.

Important translational work from WSU EACPHS.

#MedicinalChemistry #CDI

doi.org/10.1016/j.bm...

2 months ago 0 0 0 0
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Methodological Approaches for Extraction, Chromatographic and Mass Spectrometric Analysis of Lipids Lipids are a diverse class of molecules that mediate numerous structural and functional properties of cells, including trafficking, regulation of membrane proteins, and subcellular compartmentalizati...

Comprehensive review of lipid extraction, chromatography, and mass spectrometry approaches in lipidomics — emphasizing standardization and emerging opportunities like MS imaging and single-cell analysis.

Research from WSU EACPHS.

#Lipidomics #AnalyticalScience

doi.org/10.1002/bmc....

2 months ago 0 0 0 0
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Pharmacist-driven discharge antibiotic interventions improved prescribing appropriateness from 21.8% to 50% in community hospitals — without increasing 30-day adverse outcomes.

Important antimicrobial stewardship research from WSU EACPHS.

#AntibioticStewardship #Pharmacy

doi.org/10.1093/ajhp...

2 months ago 0 0 0 0
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EBPS2023 special issue: Stress, trauma and cannabinoids - Psychopharmacology Psychopharmacology -

What an undertaking this was. So proud of the collection @mayoonthebrain.bsky.social , @brainsbeesbikes.bsky.social , @cbaunez.bsky.social and I collected for the “Stress, Trauma and Cannabinoids” special issue in @psychopharmacology.bsky.social
Editorial: link.springer.com/article/10.1...

2 months ago 15 8 0 1
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@acnporg.bsky.social #ACNP2026

3 months ago 7 0 0 0