Study shows daptomycin dosing using adjusted body weight in obese patients performs similarly to traditional dosing—supporting more tailored antibiotic strategies.
WSU EACPHS #InfectiousDiseases #Pharmacotherapy
doi.org/10.2147/idr....
Posts by Christine Rabinak, PhD, MBA
New findings show STEAP4 plays a key role in liver recovery after acetaminophen injury by maintaining lysosomal iron balance and function—pointing to new treatment strategies.
WSU EACPHS #LiverResearch #TranslationalScience
doi.org/10.1097/hep....
New publication featuring WSU EACPHS in AAPS PharmSciTech.
The study explores microemulsion systems that improve omeprazole delivery through intranasal and transdermal routes.
doi.org/10.1208/s122...
#DrugDelivery #Pharmaceutics #Nanomedicine
New study featuring WSU EACPHS examines how psychoactive substances relate to cognitive function in people with multiple sclerosis. Caffeine was linked to short-term cognitive benefits, while cannabis/alcohol were associated with worse cognitive outcomes.
doi.org/10.1016/j.ap...
#MultipleSclerosis
New research from WSU EACPHS shows that 12 weeks of albuterol treatment improved pulmonary function in people living with chronic spinal cord injury.
Read it here: 10.1016/j.apmr.2026.01.013
#SpinalCordInjury #RehabilitationScience #RespiratoryHealth #WayneState
Congrats to WSU EACPHS researchers on their new paper in Arch Phys Med Rehabil exploring how machine learning + wearable devices can advance spinal cord injury research and patient care.
Read more: 10.1016/j.apmr.2025.09.025
#SpinalCordInjury #MachineLearning #Wearables #RehabilitationScience
Running a research lab is about leading people.
I created a free toolkit on the human side of lab leadership—covering hiring, mentoring, conflict navigation, lab culture, and performance management.
Open access: doi.org/10.5281/zeno...
#TeamScience #AcademicLeadership
As a neuroscientist who runs clinical trials—and someone living with metastatic breast cancer—I’m interested in collaborating with research teams as a patient research advocate.
Scientific + lived experience perspectives matter.
#PatientAdvocacy #ClinicalTrials #MetastaticBreastCancer
The first time you start a research lab, there’s no manual.
So I made one.
A practical toolkit for postdocs and early-career faculty launching their first lab: hiring, startup planning, collaborations, and building a sustainable research program.
zenodo.org/records/1888...
#research #postdoc
New research from WSU EACPHS shows that disruption of mitochondrial dynamics can trigger liver injury and tumor development through mitochondrial stress and inflammatory signaling.
#LiverDisease #CancerResearch
doi.org/10.1172/jci1...
New research from WSU EACPHS highlights how an academic–public health partnership built a genomic surveillance pipeline to track SARS-CoV-2 variants across Southeast Michigan and support pandemic response efforts.
#PublicHealth #Genomics #COVID19
doi.org/10.1038/s415...
New research from WSU EACPHS reviews strategies to deprescribe aspirin used for primary prevention of cardiovascular disease and proposes an evidence-informed algorithm to guide clinical decision-making.
#PharmacyResearch
doi.org/10.1002/phar...
Study shows D-512 protects dopaminergic cells from rotenone-induced oxidative stress and mitochondrial dysfunction — supporting its potential in Parkinson’s disease.
Research from WSU EACPHS.
#ParkinsonsDisease #Neurodegeneration
doi.org/10.3390/jpm1...
Excited to share the Psychopharm Special Issue on Stress, Trauma & Cannabinoids 14 papers examining how the endocannabinoid system shapes stress & trauma responses.
Guest edited with @connorhaggarty.bsky.social, @mayoonthebrain.bsky.social & Christelle Baunez.
link.springer.com/article/10.1...
Study shows gabapentinoids are associated with increased respiratory depression risk in hospitalized CKD patients — highlighting need for careful dosing and monitoring.
Research from WSU EACPHS.
#MedicationSafety #ChronicKidneyDisease
doi.org/10.1177/1060...
Study shows the PNPLA3 148M variant exacerbates alcohol-induced liver injury and tumorigenesis — activating oncogenic pathways and impairing detoxification.
Research from WSU EACPHS.
#HepatocellularCarcinoma #LiverDisease
doi.org/10.1016/j.aj...
Subpopulation analysis shows eravacycline achieved 77% clinical cure in enterococcal infections, nearly half VRE, with favorable safety.
Research from WSU EACPHS.
#AntimicrobialResistance #InfectiousDisease
link.springer.com/article/10.1...
Bile acid analogs targeting C. difficile spore germination safely altered bile acid homeostasis in vivo — supporting prophylactic development.
Research from WSU EACPHS.
#ClostridioidesDifficile #TranslationalScience
doi.org/10.3390/biom...
Modified OPAT regimens in MDRO infections are associated with higher costs, discharge delays & prolonged LOS, with opportunities for oral-switch therapy.
Research from WSU EACPHS.
#AntimicrobialStewardship #TransitionsOfCare
doi.org/10.1093/ofid...
Backward walking speed strongly predicts daily step goal achievement in people with MS — offering a practical clinical mobility measure.
Research from WSU EACPHS.
#MultipleSclerosis #PhysicalActivity
doi.org/10.1177/1545...
Validated stability-indicating RP-HPLC method for simultaneous quantification of brimonidine tartrate & timolol maleate — supporting quality control and greener analytical practices.
Research from WSU EACPHS.
#AnalyticalChemistry #PharmaceuticalSciences
www.nature.com/articles/s41...
An interruptive EHR alert significantly improved optimal antibiotic prescribing for acute bacterial sinusitis (7% ➡️ 30%).
Outpatient stewardship innovation from WSU EACPHS.
#AntimicrobialStewardship #DigitalHealth
doi.org/10.1017/ash....
New framework (IDEAL-R) provides guidance for evaluating the educational impact and sustainability of OSCEs in pharmacy curricula.
Education scholarship from WSU EACPHS.
#PharmacyEducation #HealthProfessionsEducation
doi.org/10.1016/j.aj...
Daily EMA data show dynamic, bidirectional relationships between psychoactive substance use and symptoms in people with MS — improving understanding of real-world symptom regulation.
Research from WSU EACPHS.
#MultipleSclerosis #MSResearch
doi.org/10.1016/j.ap...
A shortened 72-hour vancomycin prophylaxis protocol in lung transplant recipients was associated with lower odds of acute kidney injury — with similar infectious outcomes.
Research from WSU EACPHS.
#AntimicrobialStewardship #TransplantMedicine
doi.org/10.1111/tid....
Novel 5,6-fused heterocycle cholate derivatives inhibited C. difficile spore germination — and one compound prevented infection in a murine model.
Important translational work from WSU EACPHS.
#MedicinalChemistry #CDI
doi.org/10.1016/j.bm...
Comprehensive review of lipid extraction, chromatography, and mass spectrometry approaches in lipidomics — emphasizing standardization and emerging opportunities like MS imaging and single-cell analysis.
Research from WSU EACPHS.
#Lipidomics #AnalyticalScience
doi.org/10.1002/bmc....
Pharmacist-driven discharge antibiotic interventions improved prescribing appropriateness from 21.8% to 50% in community hospitals — without increasing 30-day adverse outcomes.
Important antimicrobial stewardship research from WSU EACPHS.
#AntibioticStewardship #Pharmacy
doi.org/10.1093/ajhp...
What an undertaking this was. So proud of the collection @mayoonthebrain.bsky.social , @brainsbeesbikes.bsky.social , @cbaunez.bsky.social and I collected for the “Stress, Trauma and Cannabinoids” special issue in @psychopharmacology.bsky.social
Editorial: link.springer.com/article/10.1...
@acnporg.bsky.social #ACNP2026