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Posts by SyNergy - Munich Cluster for Systems Neurology

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🧠Single-synapse mechanisms shape #visualperception. This study reveals how thalamic inputs to the #primaryvisualcortex operate at individual #synapses

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...

5 days ago 2 0 0 0

Please Repost: @genecenter-lmu.bsky.social @synergy-munich.bsky.social @enardhellmannwg.bsky.social @dickmerrill.bsky.social @lifescimunich.bsky.social @evobiolmu.bsky.social

3 weeks ago 1 1 0 0
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🧠Constitutive neuronal expression and disease-associated upregulation of #chitinases in #amyotrophiclateralsclerosis

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...

1 month ago 2 1 0 0
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🧠 #CSF #proteomics sharpens #multiplesclerosis diagnosis.

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...

1 month ago 0 0 0 0
TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism. Feiten, Astrid Feentje; Dahm, Kilian; Schlepckow, Kai; et al. Nature Communications Vol. 17, no. 1, p. 2002

New paper out: TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.: Feiten, Astrid Feentje; Dahm, Kilian; Schlepckow, Kai; et al.
Nature Communications Vol. 17, no. 1, p. 2002 | Thanks for sharing #dzne #papers

1 month ago 2 1 0 0
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🧠 Synaptic #Dopamine Storage Defect Uncovered as Key Mechanism in #Parkinson’s Disease Neurons.

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...

2 months ago 2 1 0 0
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🧠CD38 Shields #CNS Tregs From Post-Inflammatory Stress. The study shows that regulatory #Tcells persist in the CNS after the acute phase and are essential to prevent local relapses.

🔗Read a summary of the study on our website: www.synergy-munich.de/aktuelles/ne...

2 months ago 0 0 0 0
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🧠 TREM2 Levels Shape Microglial Metabolic Fitness. This study shows that microglial #TREM2 is not an on/off signal but a graded axis that tracks with microglial state and function.

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...

2 months ago 1 1 0 0

Outstanding work! – Congratulations to SyNergy member Fabian Theis!

2 months ago 1 0 0 0

Congratulation to SyNergy member Mikael Simons!

2 months ago 1 0 0 0
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🧠 Zebrafish compass neurons learn visual anchoring. Using panoramic virtual reality and two-photon imaging, we show that larval #zebrafish head-direction neurons track complex visual scenes.

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...

2 months ago 3 0 0 0
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🧠✨ Dive into #neurodegeneration at the SyNergy #ScienceDay on February 3, 2026! (in German)
Medical students get inspiring talks, expert discussions, and an emotional #Alzheimer film through Cineducation.
Curious? Join the journey from lab to clinic!
#MedicalStudents #TranslationalTeaching

2 months ago 1 0 0 0
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🧠New blood test shows the extent of brain injury after #stroke – and reveals treatment effects. Bood #biomarker brain-derived #tau (BD-tau) can track acute brain injury after ischemic stroke over time.

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...

3 months ago 1 0 0 0
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Neuer Kurs: Die #Alzheimer-Erkrankung – Dieser Kurs richtet sich an alle, die sich für das Thema Alzheimer interessieren: an Sie als Betroffene, Angehörige, interessierte Laien oder medizinische Fachkräfte. In Zusammenarbeit mit dem SyNergy Cluster.

www.synergy-munich.de/aktuelles/ne...

3 months ago 3 0 0 0
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🧠 Fully human #iPSC - derived 3D #BBB model with perfusable vessels and key BBB functions. #FOXF2 deletion causes BBB dysfunction, rescued by lipid-nanoparticle delivery of Foxf2 mRNA.

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...

3 months ago 1 1 0 0
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🧠 ApoE4 lowers the p-tau217 #tauopathy threshold.
In two independent cohorts spanning preclinical and symptomatic #Alzheimer’s disease, the study tested where #ApoE4 accelerates the amyloid-to-tau transition.

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...

3 months ago 0 0 0 0
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Exzellent erklärt - Spitzenforschung für alle 57 Exzellenzcluster – ein Podcast: Regelmäßig berichtet „Exzellent erklärt“ aus einem der Forschungsverbünde, die im Rahmen der Exzellenzstrategie des Bundes und der Länder gefördert werden. Die Reise...

Welche Prinzipien der Intelligenz verbinden Mensch, Tier und Roboter? Hört rein in die nächste Folge des #Podcast #exzellenterklaert – Spitzenforschung für alle! Das Cluster Science of Intelligence erklärt. warum Grundprinzipien von Intelligenz wichtig sind.
exzellent-erklaert.podigee.io
#Wisskomm

3 months ago 12 2 0 0
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🧠 In vivo #CRISPR screening approach identifies cytokine networks that control #macrophage function in #neuroinflammatory lesions, offering new insights into immune regulation in diseases such as #multiplesclerosis

🔗Read a summary of the study on our website: www.synergy-munich.de/aktuelles/ne...

3 months ago 0 0 0 0
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👏 Our member Qihui Zhou, has received a grant of 100,000 Swiss francs from the Frick Foundation. Zhou and her team will take a closer look at the role of the immune system in the most common genetic form of ALS.

🔗www.dzne.de/en/im-fokus/meldungen/20...

4 months ago 1 0 0 0
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🏆 👏 Congratulations to our member Arthur Liesz @isd-research.bsky.social for receiving an ERC consolidator grant for his project: TRAINED - The Role of Trained Immunity in Brain-Body Communication and Secondary Organ Dysfunction.

🔗 Read more on our website: synergy-munich.de/news-events/...

4 months ago 8 1 0 0
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Die Moleküle des Vergessens - Wie experimentelle menschliche Gehirnzellen den Weg zu Demenztherapien ebnen können Angelika Dannert, PhD, Ludwig-Maximilians-Universität München

My research at @isd-research.bsky.social, @lmumuenchen.bsky.social, @synergy-munich.bsky.social focused on more physiological, human-based models that better reflect actual disease processes - and thus contribute to the global effort towards more effective dementia treatments tinyurl.com/3thjnvzs

4 months ago 4 1 1 0

Congratulations @angelikadannert.bsky.social 👏

4 months ago 5 0 0 0
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You can currently find us at #SfN25 Neuroscience 2025 in San Diego (Society for Neuroscience) as part of Neurocenters in Germany. If you're there too, let's connect - join us at booth 3917!

5 months ago 6 1 0 1
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👃 A reduced sense of smell can be one of the first signs of Alzheimer's disease. Researchers discovered that the brain's immune system plays a significant role, indicating that it may attack neuronal fibers essential for the sense of smell.

🔗Summary on our website: synergy-munich.de/news-events/...

8 months ago 0 0 0 0
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🏆 Our member Mikael Simons receives US$500,000 for a project to investigate disease mechanisms involving tau proteins. The funding is part of the international program „Tauopathy Challenge Workshop 2025“.

🔗 Read more at @dzne.science: www.dzne.de/en/im-fokus/...

8 months ago 1 0 0 0

👇Meet our member Angelika Harbauer @harbauerlab.bsky.social

9 months ago 0 0 0 0
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🧠 A team of researchers led by Monika Leischner-Brill and Thomas Misgeld discovered that tubulin polyglutamylation plays an important role in synaptic remodeling by tagging microtubules for severing.

🔗Read a summary of the study on our website: synergy-munich.de/news-events/...

9 months ago 1 0 0 0
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Community is key for the research career “One absolutely can change their research topic after the PhD. Indeed, it is essential to adopt new perspectives and methods during the post-doc phase,” said Professor Christian Haass, speaking at the...

💭 “The most important thing for an early career researcher is to have good mentors. Ideally, this kind of a mentoring relationship is something that will naturally develop between the doctoral researcher and their supervisor."

👉 Interview w/ @haasslab.bsky.social at UEF: www.uef.fi/en/article/c...

10 months ago 3 0 0 0
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🏆 👏 Congratulations to our members Dieter Edbauer, Thomas Korn, and Christian Weber who each received the prestigious ERC Advanced Grant from the European Research Council (ERC)!

🔗 Read more on our website: synergy-munich.de/scrivito/new...

10 months ago 4 0 0 0
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👏Congratulations Arthur Liesz! Liesz was awarded the prestigious ESO Scientific Excellence Award for his contributions to the understanding of stroke and neurovascular disease. The award was presented during the Presidential Session at the ESO Conference in Helsinki.
@isd-research.bsky.social

10 months ago 1 0 0 0