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Posts by Wilhelm Lab

PhD position (m/f/d) – Dietary regulation of immune cells - Institute of Clinical Chemistry and Clinical Pharmacology - Karriereamukb | Jobs & Karriere an der Uniklinik Bonn The following part-time (25,025 hours/week) position is to be filled as soon as possible in the Institute of Clinical Chemistry and Clinical Pharmacology at the Faculty of Medicine of the Rheinische F...

karriereamukb.de/jobs/phd-pos...

3 weeks ago 0 0 0 0
Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity - Karriereamukb | Jobs & Karriere an der Uniklinik Bonn The following full-time (38.5 hours/week) position is to be filled as soon as possible in the Institute of Clinical Chemistry and Clinical Pharmacology at the Faculty of Medicine of the Rheinische Fri...

Interested in investigating dietary and metabolic regulation of immune responses? We have a PostDoc and a PhD position available in the lab.

karriereamukb.de/jobs/postdoc...

3 weeks ago 2 8 1 0

Thanks so much for invitation Steffi!

1 month ago 0 0 0 0
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Tolerance to ferroptosis facilitates lipid metabolism and pathogenic type 2 immunity in allergic airway inflammation Immune cells must modulate their metabolism to adapt to tissue constraints. Wientjens et al. show that allergen-induced ILC2s and Th2 cells require cysteine-driven glutathione synthesis to prevent fer...

Our new paper out in Immunity @cp-immunity.bsky.social Congratulations to first author Chantal Wientjens! www.cell.com/immunity/ful...

4 months ago 7 2 0 0

Lipid metabolism and redox balance are linked in type 2 immunity! We found that allergen-induced #ILC2s and #Th2 cells require cysteine-driven glutathione
synthesis to prevent #ferroptosis and
support #lipid metabolism and expansion of type 2 immune cells in #asthma.

4 months ago 4 0 1 0
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Excellence Strategy Funds Bonn Cluster for Immune Research The Bonn Cluster of Excellence ImmunoSensation will be funded for a further seven years as part of the Excellence Strategy of the German federal and state…

Hurray! ImmunoSensation will go on! 🥳
The @dfg.de just announced that ImmunoSensation3, focussing on Immune Diversity will be funded!
Let us #celebrate 7 more years of #immunology in #Bonn 🎉

www.immunosensation.de/news/immunos...

11 months ago 44 11 2 5
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Tuft cell IL-17RB restrains IL-25 bioavailability and reveals context-dependent ILC2 hypoproliferation - Nature Immunology Tuft cells constitutively express IL-25 to sustain ILC2 homeostasis in the intestine, but mechanisms driving IL-25 secretion have been unclear. Here, Feng et al. find that tuft cells express IL-17RB, ...

Congratulations Christoph an collegues!! 🎉🥳🥳🎊https://www.nature.com/articles/s41590-025-02104-y

1 year ago 2 1 0 0
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Alaaf!!!

1 year ago 3 0 0 0
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Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST Sprenger et al. used a systematic approach to identify how mitochondria remodel their metabolome in response to exercise. The diet-derived, atypical amino acid ergothioneine (EGT) accumulates in muscl...

www.cell.com/cell-metabol...

1 year ago 11 1 0 1
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Die goldene Zeit des Donald Trump Der neue US-Präsident zerstört Institutionen, Wissenschaft, die eigene Zukunft.

whoever speaks german, please read this article by constantin seibt from the @republik.ch (unfortunately there is no english translation yet)

www.republik.ch/2025/02/07/d...

1 year ago 2 1 0 0
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Revised and Extended: What's Happening Inside the NIH and NSF

Very important information to understand what is currently going on in the US. Please share and distribute www.science.org/content/blog...

1 year ago 0 1 0 0
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Kicking off the 2nd funding period of our SFB1454 on #metaflammation ! Lots of great discussions and visiting our #healthybition at the #museumkoenig in Bonn! Go and visit the exhibition until end of October 2025!

1 year ago 14 3 0 1
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🚨 Open #position! The group of Christoph Wilhelm at the University Hospital Bonn is looking for a

Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity

Application deadline is February 10!

Visit our website for more information.

#job #postdoc #science #immunology

1 year ago 3 8 0 0
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We are hiring! 📣Interested in how host metabolism, diets, #fasting and #ketogenesis affect the immune response? 👇We are offering a #postdoc position to work on the interplay of host metabolism and immunity. Apply by email or DM directly.

1 year ago 0 1 0 0

Hypoxia-inducible factor 2α promotes protective Th2 cell responses during intestinal helminth infection www.biorxiv.org/content/10.1101/2025.01....

1 year ago 2 1 0 0

Cheers

1 year ago 1 0 0 0

Would be great to be added. Cheers

1 year ago 1 0 1 0
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What defines the #WesternLifestyle and how does it impact our health and the planet? 🌍
“What the Health – Eine Welt. Deine Gesundheit!” explores these connections!
Visit our #healthybition and the accompanying program
📍 @museumkoenig until 26.10.2025
#unibonn #metaflammation #unistiftung

1 year ago 3 1 0 1
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Thermally induced neuronal plasticity in the hypothalamus mediates heat tolerance - Nature Neuroscience Ambroziak, Nencini, Pohle and colleagues identify a slowly emerging plasticity mechanism in a discrete set of hypothalamic preoptic neurons that is triggered by long-term heat exposure and that drives...

My inaugural post on Bluesky - quite fittingly, I'm thrilled to share our first study on heat acclimation, which identifies a neuronal mechanism that drives heat tolerance in mice. (www.nature.com/articles/s41... )
Here is the gist 🧵 (1/n):

1 year ago 42 14 2 4

Really glad we pulled this of together! @wachtenlab.bsky.social, Andreas Schlitzer and all PIs from #Metaflammation

1 year ago 7 0 0 0

Also, we will be hiring a postdoc and PhD. Watch this to place for more info or DM/email me in case you are interested.

1 year ago 0 0 0 0
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DFG fördert sieben neue Sonderforschungsbereiche

Thanks so much DFG for funding our CRC #1454 #Metaflammtion for another 4 years. Looking forward to unravel the immune mechanisms underlying #obesity and #diabetes together with an excellent team of scientists.
www.dfg.de/de/service/p...

www.sfb1454-metaflammation.de/sfb-1454/news

1 year ago 10 0 1 1
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Liver X receptor unlinks intestinal regeneration and tumorigenesis - Nature Liver X receptor drives epithelial Areg-mediated intestinal regeneration, while preventing tumour growth through adaptive immune responses.

Congratulations @ejvillablanca.bsky.social and colleagues, super nice paper! www.nature.com/articles/s41...

1 year ago 5 1 1 0

many new members, many still to join #neuroscience #immunology

1 year ago 9 2 0 0

Please add

1 year ago 1 0 0 0
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Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19 - Nature The ketone body β-hydroxybutyrate can be used as an alternative carbon source by T cells to maintain their function during severe respiratory viral infections, including infection with&...

Ever wondered how fasting is benefiting the adaptive immune response? In @Nature we show that #ketogenesis promotes the function of #tcell in severe respiratory viral infections by providing #ketonebodies BHB as carbon source. Final edited version: www.nature.com/articles/s41...

1 year ago 54 17 2 1