Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.

Only 9 years to go from today, until AI cures all disease 🚀 🚀🚀

Really looking forward to it!

Professor in Synthetic Organic Chemistry University of California, Irvine is hiring. Apply now!

Please RT!

The Dept of Chemistry at UC Irvine invites applications for a tenured faculty position in Synthetic Organic Chemistry. Deadline: July 1, 2026.

More information about the position can be found here: recruit.ap.uci.edu/JPF10109

@uciphyssci.bsky.social

High-resolution cryo-EM structures of small protein-ligand complexes near the theoretical size limit pubmed.ncbi.nlm.nih.gov/41980966/ #cryoEM

At the time I found the massive mito preps we did from cow hearts that required hours in the cold room exhausting but actually with hindsight I do miss the camaraderie! I can also understand @cellarchlab.com's enthusiasm to not be in his office 😂

It’s done!! Molecular architecture of the ciliary base in mammalian multiciliated cells! A study 13 years in the making 👴, thanks to collab with @stearnslab.bsky.social + @centriolelab.bsky.social & visionary work by @computingcaitie.bsky.social, who integrated native #cryoET with #XLMS & #UExM 🧪🧶🧬🔬

2D classes of a 58 kDa particle collected on a 100 kev Tundra electron microscope

2D classes of the 58 kDa sample collected on the 100 keV Tundra TEM with a Falcon C detector at @nusbf.bsky.social @newcastleuni.bsky.social. Still much work to do to optimise the sample & data collection but its cool to see what a 100 keV TEM is capable of. #cryoEM @recon4imd.bsky.social

AlphaFold as a prior: experimental structure determination conditioned on a pretrained neural network Nature Methods - ROCKET improves experimental structure elucidation by integrating implicit structural knowledge from OpenFold, a trainable reimplementation of AlphaFold2, with X-ray...

ROCKET 🚀 inference-time optimization of AlphaFold to fit structural data is published! rdcu.be/fa9YH
Since our preprint, we’ve pushed it to regimes where other methods break: low resolution, weak signal, real experimental edge cases. Here’s what we learned: 1/15

Come join us @uwinnipeg.bsky.social Chemistry! Tenure-track Assistant Professor in Biochemistry. Submit by April 20 for full consideration. Please share widely and DM or email me if you would like more info. #chemjobs #facultychemjobs

Simply one of the most important developments in protein structure modelling. Ever. Let that sink in

Released today 1 April

Check out our first lab preprint: A real team effort to understand the Plasmodium GAPM proteins, which form part of a essential bridge between the parasite's cytoskeleton and motility apparatus. Below is a sneak peek of some beautiful microscopy - light and electron! www.biorxiv.org/content/10.6...

(1/7) How does T. brucei achieve a 140-fold stoichiometric excess of VSG mRNA over upstream ESAGs from a single polycistronic unit?
Our latest research in @natmicrobiol.nature.com reveals a mechanism of spatially regulated RNA decay to fine-tune expression of virulence genes

Job Opportunity at University of Leeds: Associate Professor of Plant Science Associate Professor of Plant Science Salary: Grade 9 (£61,759 - £73,708 p.a, depending on experience)This role will be based on the university campus, with scope for elements of the job to be undertak...

Apply before April 23rd to join us as Associate Professor at Leeds
jobs.leeds.ac.uk/vacancy.aspx...

Now this is the future of TB research 👏

39 Keystone Symposia & @gatesfoundation.bsky.social scholarship awardees at #KSTB26.

With ~1.5M TB deaths each year, these early-career scientists are driving progress through collaboration and new ideas.

@maxgg.bsky.social @breealdridge.bsky.social

Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...

1) The Herzik lab is excited to announce our newest preprint in collaboration with the Grotjahn lab! We have developed a surfactant cocktail that seeks to overcome one of the more nefarious problems in #cryoEM, Air-water interface (AWI)-induced damage and preferred orientation (PO).

Oseltamivir aziridines are potent influenza neuraminidase inhibitors and imaging agents pubmed.ncbi.nlm.nih.gov/41871250/ #cryoEM

🚨 Preprint alert!

We solved the structure of human NSUN2 bound to Asp tRNA, revealing how it installs m⁵C and recognizes RNAs
#CryoEM #RNABiology

A collab between Casañal & Gullerova labs, with @miclass.bsky.social and me working side by side as co-first authors

🔗 doi.org/10.64898/202...
(0/7🧵)

We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo.

#OpenSoftwareAcceleratesScience

Associate Senior Lecturer/Assistant Professor in Molecular Microbiology The Department of Biology conducts research and teaching in many subject areas such as ecology, evolutionary biology, organismal biology and molecular biology. A total of approximately 300 people curr

Associate Senior Lecturer/Assistant Professor position in Molecular Microbiology available at Lund University, Sweden:
lu.varbi.com/en/what:job/...

We also often get this as a contaminant so it’s fun to see how it looks!

When it rains myco publications in pours myco publications!
Now out in PNAS tinyurl.com/2a6833n4
When @zestytoast.bsky.social accidentally isolated the long-chain acyl-CoA carboxylase, we quickly realized we were looking at a fascinating machine essential for building the mycobacterial membrane...

Oh god, now I’ve read this it’s not leaving my head

New OpenFold3 preview out! (OF3p2)

It closes the gap to AlphaFold3 for most modalities.

Most critically, we're releasing everything, including training sets & configs, making OF3p2 the only current AF3-based model that is functionally trainable & reproducible from scratch🧵1/9

Happy to share that my research center at Rutgers NJMS is hiring tenure-track faculty at all ranks! We are broadly interested in infectious disease research from experimental to computational. Please ask questions and join our community!

jobs.rutgers.edu/postings/139...

Excited to announce I’m starting a new lab at @gmivienna.bsky.social (Vienna BioCentre) in Sept 2026

We study how carbon fixation is inherited and maintained in algae using cryo-ET, imaging, environmental sampling&more

Looking for people who want to build the lab together, get in touch!

#teamtomo

I do hope JBC moves to an open review process. I’m very happy for the world to see the hard work I’ve put in and very happy to put my name to it also

It feels like JBC's approach of having a pool of reviewers that literally have to pass an exam before they are EBMs is more relevant than ever

This recently happened to us, with similar tells… infuriating.. you can see how it unfolded in the public peer review file: static-content.springer.com/esm/art%3A10...

It is indeed, not sure I would have been so professional. Well done @reichowlab.bsky.social & team