Challenging C(sp³)–H bond functionalization made possible!🔬
Keiji Mori & co-workers report benzylic #functionalization of electron-deficient aromatics using a methoxy-directed strategy, followed by #onepot MeOH elimination, enabling efficient access to dihydronaphthalenes🧪

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How can noncovalent interactions power catalytic reactions?🧪 Mal & coworkers explore the role of π-stacking, EDA complexes, and anion–π interactions in #supramolecular catalysis, opening new paths toward sustainable organic synthesis✨

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Discover the elegant Diels–Alder strategy behind the first #TotalSynthesis of #Thamnosin by Dethe & Dherange🧪 By fine-tuning reaction conditions, two distinct modes of diene dimerization were unlocked to construct this complex natural product🎯

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Explore the power of Cp*Rh(III)-catalyzed C–H activation by Qiufeng Huang & co-workers!✨ This account highlights how NH- #indole directed strategies are transforming simple #arylindoles into complex polycyclic compounds with anti-tumor potential💊
#rhodium

👉 buff.ly/BrdP1vR

First report of W-catalyzed regioselective allylic #sulfonylation by Wenbin Xu🚀 Secondary & tertiary carbonates → allylic sulfones with excellent b/l selectivity. Noble-metal-free & synthetically versatile✨
#tungsten

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Explore a powerful deaminative strategy for selective #halogenation by Lu & Cui!✨ By converting native alkylamines into radicals, this method installs Cl, Br, and I at highly congested sites that conventional tools can't reach🎯

👉 buff.ly/TPRXbKk

Fernández-Rodríguez & co-workers explore biaryl-embedded 1,7-enynes as platforms to build diverse dibenzofused #polycycles🧪 Gold(I), Brønsted acids & boron reagents tune the reaction outcome — paving the way for controlled polycyclic design🚀
#boron #gold

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Rajendra Rohokale & co-workers report the enantioselective synthesis of 2-azido-norfuranomycin from a D-glucose-derived chiral synthon⚗️ Key steps include oxidative cleavage, azido-olefin formation & ring-closing metathesis to build the dihydrofuran core🔬
#TotalSynthesis

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Join Thieme #Cheminar “Boron as a linchpin in catalysis”🧷 featuring Profs. Hirohisa Ohmiya @hirohisaohmiya.bsky.social 🇯🇵, Elena Fernández 🇪🇸, James Morken 🇺🇸 & chaired by our EiC Prof. Martin Oestreich @silicon-martin.bsky.social 🇩🇪

📅 April 14, 2026
⏰ 4 PM (CEST)

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Vinod Kumar & co-workers spotlight #cyanamide as a dual-reactive building block unlocking ureas, guanidines, hydantoins & more🧪 From new chlorinating reagents to applications in medicine & agriculture — big impact from a tiny motif🚀

👉 buff.ly/J7j9PXi

Shining new light on #epoxides 🔬 Huang & co-workers unveil a visible-light-driven route to α-amino epoxides via an oxa-π,σ-methane rearrangement🧪 Mild, selective, and versatile—breaking past traditional synthetic limits
#photochemistry

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Streamlined marine alkaloid syntheses 🌊🔬 Kaliappan & co-workers report concise #TotalSynthesis of denigrins E & D, plus formal syntheses of polycitones A & B⚡ Microwave-assisted Paal–Knorr pyrrole formation powers these high-yield, step-economical routes🚀

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Explore the full potential of #quinoxaline ✨ Patel & co-workers reveal sustainable strategies—bis-functionalization, #photochemistry ☀️, C3–H activation, spiro-etherification—for broad, scalable, green syntheses 🌱

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Don’t miss the Thieme #Cheminar “Thieme Chemistry Journals Awardees 2026”🔬 with Drs. Yagnaseni Roy, Javier Mateos, Clément Ghiazza @clementghiazza.bsky.social, Elisabeth Kreidt @ekreidt.bsky.social & Prof. Charles Loh

📅March 30, 2026
⏰16:00 (CEST)

Register 👉 buff.ly/GLQwo3T

Ni-catalyzed adaptive migration unlocks dual alkyl intermediates for enantioenriched α-arylated ketones! A game-changing strategy by Wei Shu & co-workers⚡
#nickel #hydrocarbonylation

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Following their widely cited #NewTools article, Thomas S. Teets’s group has launched a searchable database for #photosensitizers buff.ly/VCPsybf

Filter by photophysical & redox properties to quickly find the right catalyst⚡

Read here👉 buff.ly/HFSN9LS
Updates and new entries welcome: tteets@uh.edu

✨Unlock the power of alkynes as 1,2-dicarbonyl #surrogates! Explore mild & efficient oxidations via I₂/DMSO & NIS/DMSO in heterocycle synthesis by Bibhuti Bhusan Parida & co-workers🔬
#Kornblum

👉 buff.ly/MKLBKHQ

Ni-catalyzed asymmetric reductive #CrossCoupling 🔥Using a Ni/Biox platform, this method by Qiu & Gong delivers enantioenriched tertiary α-aryl acetals/ketals with steric/electronic effects guiding selectivity✨
#nickel

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#Furans & benzofurans in pharma! 🧪 Kotha & Solanke showcase RCM & SM coupling for industrially relevant scaffolds—plus a peek at greener, next-gen methods like flow & photoredox chemistry✨🔬

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Expanding #helicene chemistry🌀 Milan Kivala & co-workers report a π-expanded [5]helicene featuring a seven-membered tropone unit—revealing a highly twisted structure, lowered racemization barrier, and key insights from X-ray and DFT studies🧪
#nanographene

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Fighting multidrug-resistant cancer🧬 Rohit Bhatia @rohitbhatia10.bsky.social & co-workers review five-membered heterocyclic hybrids as versatile anticancer scaffolds with strong efficacy and lower toxicity💊
#anticancer

Read more 👉 buff.ly/sDg5PHD

From lab to pilot scale🔬➡️🏭 Yadong Wu & co-workers develop a practical, four-step route to lurasidone hydrochloride with purifiable intermediates and 42% yield, ideal for industrial production 💊

Read more 👉 buff.ly/Hspyiok

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Tricking bacteria to stop #biofilms 🦠 Chutima Jiarpinitnun & co-workers design squaramide AHL mimics that interfere with P. aeruginosa quorum sensing, blocking biofilm formation without killing cells⚡
#squaramide

Read more 👉 buff.ly/QdDRPho

Metal-free asymmetric synthesis🌱Chandrakumar Appayee & co-workers showcase how chiral secondary #amines, especially proline-derived, drive enamine & iminium #catalysis for diverse C–C and C–heteroatom bond formations under eco-friendly conditions✨

Read more 👉 buff.ly/vNjbLym

Accessing chiral 1,2-amino alcohols✨Gong  & co-workers developed a diastereoselective addition of Grignard & MeLi reagents to a pyrrolo-oxazolone scaffold, giving diverse CAUAs with terminal esters.
#Diastereoselectivity

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C2-selective Pd-catalyzed C–S #coupling! Jackson & Neufeldt report new conditions enabling rare C2 #functionalization of 2,4-dichloropyrimidines, complementing traditional C4-selective methods and raising intriguing mechanistic questions about oxidative addition ✨
#catalysis

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Cracking a century-old puzzle🔍 Andrew Smith & co-workers explore [1,2]-rearrangements of #ammonium ylides—tackling selectivity, probing radical pathways, and redefining how these elusive allylic shifts may occur✨
#organocatalysis #radicals

👉 buff.ly/LOT16BC

Asymmetric Ni #catalysis at work🧪 Takuya Kurahashi & co-workers introduce a tyrosine-derived FOXAP ligand enabling aziridine–imine cycloadditions—building #imidazolidines with up to 97% ee via enantioconvergent design🔬
#nickel

👉 buff.ly/vH5n6jI

Join Thieme #Cheminar “Strain-Release Chemistry”🔬 with our speakers Dr. Durga Prasad Hari (🇮🇳), Prof. Jérôme Waser (🇨🇭) @lcsolab.bsky.social & Prof. Peter Wipf (🇺🇸), hosted by our assoc. editor Prof. Akkattu T. Biju

📅February 24, 2026
⏰11 AM (GMT+1)

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