DNAharvester's workflow.
We present DNAharvester 🎉🦴🚜🧬
A pipeline to process highly degraded ancient DNA data that integrates metagenomic filtering, competitive mapping, multiple alignment strategies, reference bias evaluation and much more.
GitHub: github.com/NBISweden/DN...
Preprint: www.biorxiv.org/content/10.6...
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Our new pipeline for analysing highly degraded genomic DNA data is now available at biorXiv!
Study led by Bilal Sharif
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📣 EvolDir is now managed by @eseb.bsky.social!
We are delighted to be taking the reins and express our gratitude to both Brian Golding who began this service to the community in the mid-1980s and to @rdmpage.bsky.social who ran this account until now 👏
You can now find evoldir here: evoldir.net
2 days ago
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New paper alert 🚨
A study led by #CPGSthlm researchers found DNA from a bear in 9.6k year old lake sediments. This potentially rewrites the history of brown bears in Scandinavia! 🧬🐻🐾🏔️🧊
Check @officialernst.bsky.social thread 👉
bsky.app/profile/offi...
OA article 👉 www.pnas.org/doi/10.1073/...
1 day ago
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GBE | Comparative Genomics and Phylogenomics of the Mustelinae Lineage (Mustelidae, Carnivora)
Totikov et al. present a comparative and phylogenomic study of the Mustelinae, uncovering striking variation in genome-wide heterozygosity and genome size, marked homozygosity in some Asian lineages, and remarkable diversity in widespread species.
🔗 doi.org/10.1093/gbe/evag014
#genome #evolution
1 month ago
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Congratulations to my former student Lei Wu who recently published "Parallel divergence with shared barriers and niche
separation between two sympatric avian species groups" (dx.doi.org/10.1111/jse....) (Open Access). Willow Tit Poecile montanus and Marsh Tit P. palustris species groups in China
1 month ago
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I'm super excited to share that this article was published today in Science! www.science.org/doi/10.1126/...
All made possible by the fantastic group of donors, volunteers and scientists at The American Chestnut Foundation (tacf.org), HudsonAlpha Institute for Biotechnology, and our collaborators.
2 months ago
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one more week to apply for a 4-years PhD position with me to work on the macrogenomics of sea warming.
Deadline: Jan 18th 2026
#MarineGenomics #EvolutionaryBiology #PopGen #Bioinformatics #conservationgenomics #consgen #conservationgenetics
3 months ago
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PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
New paper out in the Proceedings of the National Academy of Sciences. We identify regulatory variants shaping embryonic heat tolerance in Drosophila, linking lab selection to clinal and seasonal patterns in wild populations. Link: www.pnas.org/doi/10.1073/...
3 months ago
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MBE | SLiM 5: Eco-evolutionary Simulations Across Multiple Chromosomes and Full Genomes
Haller, Ralph & Messer present SLiM 5, a major extension of the SLiM simulation framework for simulating multiple chromosomes, enabling a heightened level of realism for full-genome simulations.
🔗 doi.org/10.1093/molbev/msaf313
#evobio #molbio #compbio
3 months ago
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Nucleotide diversity is a poor predictor of short-term adaptive potential
A capacity to adapt is essential for a population to avoid extinction in a changing world and is recognised as a global conservation priority. Adaptation requires additive (heritable) genetic variatio...
I'm excited to share that our preprint is now available on bioRxiv! Our study challenges the widespread use of molecular genetic diversity as a predictor adaptive potential, with important implications for how genetic data is used to inform conservation decisions.
www.biorxiv.org/content/10.6...
3 months ago
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New work from @miyapan.bsky.social and our team, bringing ant, bee, and wasp labs together. @chuanxinyu.bsky.social shows that the ANTSR locus we discovered in ants has determined sex for 150+ My across bees and stinging wasps 🐜🐝, despite virtually no sequence conservation 😮 doi.org/10.1073/pnas...
3 months ago
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Inversions support both parallel and location-specific adaptations in snail ecotypes
Replicated hybrid zones between ecotypes established over within shore environmental gradients provide an opportunity to study the genomic architecture of barriers to gene flow. The marine snail Litto...
New results on Littorina fabalis ecotypes! 🐌
Inversions aren't just enabling parallel adaptation to wave exposure in France & Sweden, they're also hotspots for site-specific differences, including a striking color QTL associated with one inversion but only in France.
www.biorxiv.org/content/10.6...
3 months ago
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Really interesting work, showing that animals with winter-white coats may be more in danger of predation under climate change, compared to those with winter-brown coats.
#seasonalcamouflage
4 months ago
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We have 🐟 herring pre print!
Our new study reveals that ancient gene flow between Pacific and Atlantic herring played a key role in helping Atlantic herring adapt to the brackish waters of the Baltic Sea.
www.biorxiv.org/content/10.1...
5 months ago
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🧬 Just out in Bioinformatics Advances: “tskit arg visualizer: Interactive plotting of ancestral recombination graphs.”
Read the full paper here: https://doi.org/10.1093/bioadv/vbaf302
Authors include: @kitchensjn.bsky.social, @yanwong.bsky.social
4 months ago
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🌊 🐟🦭🐋🐧 I have a PhD position available (4 years, start Mid-2026) at NRM Stockholm to work on the macrogenomics of sea warming.
Apply here:
recruit.visma.com/spa/public/a...
#PhD #MarineGenomics #ClimateChange #EvolutionaryBiology #PopGen #Bioinformatics #conservationgenomics
4 months ago
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🦣 🤯 🦣 🤯 🦣
Video of woolly mammoth leg discovered in the Siberian permafrost!
Researchers from #CpgSthlm and SciLifeLab have now, for the first time ever, identified signatures of gene activity in frozen mammoth remains!
www.cell.com/cell/fulltex...
5 months ago
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A very big shoutout to @joao-pedro-marques.bsky.social, who coordinates this partnership and convinced me to tag along in developing this project, and to all co-authors for their input!
5 months ago
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Details of the framework used to implement a formal partnership between a research institution and a school to develop scientific projects with students.
We detail the framework we have been using to implement scientific projects with students, as part of a formal partnership with a local school, and we assess students' project experience through a case study pilot survey. Our results suggest these projects promote science engagement & literacy.
5 months ago
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Figure 1A from the paper shows the distribution of black-headed (western) and rose-breasted grosbeaks (eastern) throughout North America. Small illustrations of males of each species are shown. Black-headed has a rusty orange breast and black head, while rose-breasted has a small reddish bib with a bright white belly. There is an inset map of South Dakota showing the transect across the hybrid zone
The first Aguillon Lab paper is officially out in early view at Evolution!! Led by postdoc @devonderaad.bsky.social, we’ve explored the hybrid zone between black-headed and rose-breasted grosbeaks in the Great Plains. #ornithology #hybridization #speciation #evolution doi.org/10.1093/evol...
7 months ago
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Recombination-aware phylogenomics
Phylogenetic variation, recombination rate evolution, and comparative genome structure and organization have typically been explored in isolation. The…
Really great review on recombination-aware phylogenomics.
Highlights how we can leverage recombination rate variation to resolve the evolutionary histories of species, and better understand the evolutionary processes of speciation and hybridization.
www.sciencedirect.com/science/arti...
8 months ago
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I'm super excited to share our new paper on Norwegian lemming genomics just published in @pnas.org!! Read the paper here: www.pnas.org/doi/epub/10....
Summary ⬇️
9 months ago
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