CXCR3 as a flow-sensitive modulator of developmental #Angiogenesis in #Zebrafish 🐟
CXCR3i (AMG487), CXCR3a (VUF11222), cxcr3 triple KO🐟▶️
⏫cranial vascularity
⏬pericyte investment (CXCR3▶️⏫pdgfb)
@astratman.bsky.social #ATVB 2024
www.ahajournals.org/doi/10.1161/...
Always appreciate a Hao feature!
Join us today! Free for everyone who would like to attend.
NAVBO is joining the January 21st Day of Action to urge increased FY26 funding for medical research! 🧪🫀🔬
✅ Join us: speak4.app/lp/6t01dslt/...
#SupportCures #FundMedicalResearch #CuresCantWait
Over the last century, research has helped improve the
early detection and treatment of serious diseases. But
future progress is at risk unless we continue federal
funding for medical research.
#AmericansForMedicalResearch
Over the last century, research has helped improve the
early detection and treatment of serious diseases. But
future progress is at risk unless we continue federal
funding for medical research.
#AmericansForMedicalResearch
super resolution microscopy image of neutrophils to visualize the depolymerized f-actin (phalloidin staining visualized in yellow) in cells that took up lipid (visualized in magenta)
Super excited to share our newest story! We found that despite their well-known reliance on glucose, neutrophils also like lipids! Lipid uptake is induced by immune signals, and we think this is important in atherosclerosis and other lipotoxic metabolic diseases!
www.biorxiv.org/content/10.1...
Excited to be involved with this work driven by @dremilygoldberg.bsky.social and her team! Read the preprint now!
"Neutrophil TLR2 signaling promotes lipid accumulation and vascular plaque growth"
Join us! Abstract submissions due in one week
A sign that says “small fish big impact fund scientific research” with a picture of an adult and larval zebrafish
I stood up for science! Shoutout to @astratman.bsky.social for the sign idea. #StandUpForScience #standupforscience2025
My colleague Dan beat me to the punch but I am so thankful that my hometown paper (and others) was willing to share this with the community.
Exciting news! We are launching Applied Health Analytics for Delivery & Innovation (AHADI) led by Abdisalan Noor and @jalinegerardin.bsky.social. AHADI is an organization focused on Africa that works for countries on #SelfRelianceInHealthAnalytics Learn more here 👉🏾 shorturl.at/8XQVN.
Hello #Bluesky! We'd like to introduce ourselves...
We are the WashU Ciliopathy Research Group - a multidisciplinary team of investigators at Washington University in St Louis that perform fundamental, translational, and clinical research on #ciliopathies.
Follow us for updates from the group! 👇
NK: PIEZO1 p.Pro42Leu causes narrowed aorta in zebrafish, in work by @astratman.bsky.social lab #ASHG24
This one is a great collaboration with @astratman.bsky.social on characterization of U12-spliceosome gene ZCRB1, U12-intron splicing and its role in ciliogenesis and WNT-signaling. Halloween passed but we can still get headless zebrafish. #RNA #splicing #RNAbiology
www.biorxiv.org/content/10.1...
*Tap tap tap* Is this thing on? New paper alert from the lab, featuring first author Dymonn Johnson and a whole host of collaborators who helped this paper come together. We couldn't have done this without the whole team! www.biorxiv.org/content/10.1...
Check out our new paper on mural cell populations in the developing zebrafish! What transgenic marker should be used to see mural cells in different vascular beds over time? Read on to find out about Pdgfrb vs Tagln expression-with some new twists: anatomypubs.onlinelibrary.wiley.com/doi/10.1002/...
Go check this out! Fun to collaborate on work driven by the Nicoli Lab 🐟🧠🔬
utah.peopleadmin.com/postings/153... Assistant/Associate Professor in Computational Genomics at Univ Utah
🧪 3 tenure-track microbiome faculty job openings in Hawaii! 🌞 🏄🏽♀️ 🍄 🧫 🧬 🦃
Super proud of this work! Still much to do, but excited to see where it takes us!
thanks Hao for the feature! 😀
cxcr3.1/3.3 as #EndothelialCell flow sensor
CXCR3 inhibition (AMG487) in #Zebrafish🐟
->⏫🧠vascularity +⏫pERK1/2 in EC
->⏬pdgfb in EC->⏬🧠#Perciyte recruitment
Any distinct/redundant function vs CXCL11-CXCR4 axis?
1/3🧵
@astratman.bsky.social bioRxiv 2023
www.biorxiv.org/content/10.1...
WashU CellBio is launching a new program called the RISE Fellows Program: cellbiology.wustl.edu/education/ri...
This is a mentored-fellowship to tenure track faculty position open to defending PhD candidates/< 3rd year postdocs. All areas of cell biology considered. Reach out with any questions!
Congrats @teresaomeara.bsky.social on this beautiful work!!
New preprint from the lab! Gain and loss of CXCR3 activity in endothelial cells alters their vessel expansion and stabilization potential.
www.biorxiv.org/content/10.1...
One reason I got into science social media was a small project to highlight women whose work I admire in neural engineering & systems/comp neuro. Since X is dying, I'm migrating those posts here. To give folks their due, we'll go one post per day.
Follow along to celebrate some amazing science!
Excited for postdoc Javier Abello's appointment to WashU's TriMED T32! Exciting working coming- stay tuned!
Yea!!
I'd like to be added, thanks!