Out in @natmethods.nature.com: More dyes. They work. Quite well. And blink. Pick the one that fits your target, your technique, and your labeling density. With too many collaborators and institutes to list, but anchored at @hhmijanelia.bsky.social www.nature.com/articles/s41...
We are looking for an experienced light microscopy specialist, motivated to support our users in the Advanced Light Microscopy Facility at EMBL Heidelberg.
embl.wd103.myworkdayjobs.com/en-US/EMBL/j... -closing date 11 May 2026 @eurobioimaging.bsky.social @globalbioimaging.bsky.social
Whole-organism spatial transcriptomics at single-cell resolution in C. elegans www.biorxiv.org/content/10.64898/2026.04...
The famous ‚fluorescence depends on the environment‘ lecture! Need more light? Consider adding base to your sample:)
Painted 100+ lung organoids for Easter, stained with live-cell Cell Tracker/ @spirochrome.com dyes, imaged at our @leicamicrosystems.bsky.social Viventis Deep light-sheet 🔬 at Charité (soon @Si-M - Der Simulierte Mensch) and visualized using inverted lookup tables designed by @christlet.bsky.social
Congrats! This looks like a cool method!
Using #SingleMolecule imaging we find that TFs:
-boost co-transcriptional #ribosomal #RNA processing!
-their binding #dynamics fundamentally differ for mRNA (transient) versus rRNA #transcription (stable)!
@biorxivpreprint.bsky.social Anastasiia Chaban @embl.org
www.biorxiv.org/content/10.6...
#VirtualPub We welcome Valentin Dunsing-Eichenauer, Charité Universitätsmedizin Berlin, on "Functional & deep imaging of #organoids via light-sheet #FLIM and two-photon microscopy."
🗓️ Fri, March 27 @ 13:00 CET
Register ⤵️
www.eurobioimaging.eu/events/funct...
I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.
ChromSMF preprint is out!🚀
tinyurl.com/ChromSMF
We often piece together chromatin regulation layer by layer from separate assays. But this can be limiting!
In @arnaudkr.bsky.social's lab, we developed a method to directly study multiple layers on the same DNA molecule! 🧬
What does this unlock? ⬇️
🔥 How does CTCF shape enhancer–promoter communication?
In our new preprint, we systematically test how the position and orientation of CTCF binding sites (CBSs) influence gene regulation at the mouse Sox2 locus.
🧪 full paper can be found here: www.biorxiv.org/content/10.6...
Screenshot from Google Scholar showing the paper about the tool "RS-FISH" has 100 citations.
RS-FISH reached 100 citations 🥳 I always love checking the projects that use it, so cool to see all these different studies! Thank you all for using our tool!
We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).
Ever wondered how a eukaryotic transcription factor finds its specific DNA motif in the vast genome? In this preprint, we directly measured the dynamics of this search process in living cells, revealing a cooperative mechanism mediated by disordered regions. 1/10 doi.org/10.64898/202...
Calling all OME Community members, contributors, and lurkers! Please take a minute to answer the OME 2026 Community Survey (docs.google.com/forms/d/e/1F...) to help us prepare for discussing the future of OME governance during the OME 2026 Community Meeting at the end of April.
🚨 Job Alert - Please share! 🙏
Interested in 3D gene regulation in development & evolution? 🤓🧬
💥 Our lab at @cabd-upo-csic.bsky.social is expanding!
We’re recruiting:
✅ PhD students
✅ Postdocs
💻🧪 Experimental or computational backgrounds welcome
👇 Details below
I use Hoechst, DAPI has an interaction with my oxygen scavenger buffer that dims the fluorescence!
Get to know Thomas Schlichthärle, our newly appointed professor of #AI-guided #ProteinDesign, in the latest NewIn episode. He wants to use custom-designed #proteins to advance the development of new #medicines: go.tum.de/484027
#HightechAgendaBayern
▶️ youtu.be/G-pt28HJpA8
📹& 📷ProLehre
Join us at CSHL for Quantitative Imaging: From Acquisition to Analysis—two weeks of advanced imaging, analysis, and hands-on labs with cutting-edge microscopes and open source software!
📅 April 6–21, 2026
📝 Applications due Friday Jan 30, 2026
🚨 Alarm!!! 🚨
AI/ML course for microscopy image analysis!!! 🧐
In 2026 at Janelia (@hhmijanelia.bsky.social), no tuition, housing and meals provided! Isn’t that borderline unbelievable?!?
20 students, ~14 TAs and lecturers
🗓️ June 4-18 2026
✍️ Jan 15 2026 ✍️
🔁 pls!!
www.janelia.org/you-janelia/...
Pinging @carmofonlab.bsky.social, do you maybe have a suggestion?
New paper out! Combining single-objective light-sheet microscopy and time-resolved SPAD array detection, we massively accelerate fluorescence lifetime imaging (FLIM) compared to confocal FLIM, making FLIM applicable to 3D specimen such as organoids and embryos.
www.nature.com/articles/s42...
Very happy to share that starting in January, I will take on a new position as microscopic imaging facility leader and researcher at Der Simulierte Mensch (Si-M), a new joint institute by Charité and TUBerlin, which aims at advancing human model systems (e.g. organoids) for biomedical research.
Congrats Valentin! Excited to visit in the future!
Such a fun workshop idea!
Screenshot of a Tweet pointing out that academic spam is actually in its own way kind of encouraging.
I think about this post every day 🧪
We are excited to welcome @fueyoraquel.bsky.social, @sedonamurphy.bsky.social, and @jmstein.bsky.social as new group leaders at our institute!
Read more about their work:
--> www.molgen.mpg.de/2025-10-31-n...
All three are recruiting in the IMPRS PhD Call!
--> www.molgen.mpg.de/IMPRSPhDproj...
We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3
Oh yes-the one and only Robert Haase @haesleinhuepf.bsky.social
From #GrandTheftAuto to the impact AI is having on #bioimaging.
+the challenges of creating AI courses for bioimage analysis, & his unique perspective as a programmer-turned-biologist.
Stream- bit.ly/microscopist...
@globias.bsky.social
